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Tear protein analysis in presumed congenital alacrima.

Clin Ophthalmol

December 2018

Department of Ophthalmology, Kyorin University School of Medicine, Tokyo 181-8611, Japan,

Purpose: To establish a method for the measurement of 5-fluorouracil (5-FU), and tegafur (FT) in tear samples from patients treated with oral fluoropyrimidine anticancer agent S-1.

Study Design: Cross-sectional study.

Methods: High performance liquid chromatographic (HPLC) method reported for plasma samples was modified for tear samples.

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