5,155 results match your criteria: "university of sciences[Affiliation]"

A new genus and two new species of Cossidae (Lepidoptera: Cossoidea) from India and Pakistan.

Zootaxa

November 2024

Zoological Survey of India; M-Block New Alipore; Kolkata 700 053; West Bengal; India.

Aroriella gen. nov., which includes two new species, A.

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Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial infiltration and pannus formation, and its rising incidence is significantly contributing to the global disability rate. Despite advances in biological drugs, no treatment has successfully cured or averted its progression. Consequently, natural drugs are being explored as alternative therapeutic strategies.

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Diffuse large B-cell lymphoma (DLBCL) is a rare and aggressive form of non-Hodgkin lymphoma (NHL) that can occur in the breast. This case report details the case of a 48-year-old postmenopausal woman diagnosed with primary breast DLBCL after presenting with a painless, rapidly growing mass. Imaging studies, including ultrasound and mammography, indicated significant breast involvement, confirmed by histopathological analysis revealing large atypical lymphoid cells.

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Urinary tract infections (UTIs) are the second most prevalent infectious disease with being the most common etiological agent behind these infections, affecting more than 150 million people globally each year. In recent decades, the emergence of multi-drug resistant (MDR) pathogens has rapidly escalated. To combat antimicrobial resistance (AMR), it is important to synthesize new biologically effective alternatives like ionic liquids (ILs) to control the bacterial infection and their spread.

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Ischemic stroke is a cerebrovascular disease that affects the blood vessels and the blood supply to the brain, making it the second leading cause of death worldwide. Studies suggest that immune cells play a dual role during the inflammatory and recovery phases of stroke. However, in-depth investigations of specific cell subtypes and their differentiation trajectories remain to be elucidated.

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One Health approach is a global public good (GPG) that invites governance to maximize the health of humans, animals, and the environment by shaping interdisciplinary and cross-sectoral collaboration. This paper explores the theoretical foundations, practical applications, and ethical considerations of the One Health governance architecture. At the theoretical level, One Health governance invites systems thinking and involves collaborative efforts among multiple stakeholders, applying across multi-layered scenarios and requires public-private partnership (PPP).

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Docosahexaenoic acid (DHA, C22:6 n-3), a predominant omega-3 polyunsaturated fatty acid in brain, plays a vital role in cerebral development and exhibits functions with potential therapeutic effects (synaptic function, neurogenesis, brain inflammation regulation) in neurodegenerative diseases. The most common approaches of studying the cerebral accretion and metabolism of DHA involve the use of stable or radiolabeled tracers. Although these methods approved kinetic modeling of ratios and turnovers for fatty acids, they are associated with excessive costs, restrictive studies, and singular dosing effects.

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Article Synopsis
  • * Recent studies highlight its pharmacological properties, particularly those of methyl antcinate A (MAA), which shows significant anti-cancer, anti-inflammatory, and gastro-protective effects.
  • * There is a need for further research and clinical trials to better understand MAA's anti-tumor effects and to explore the structure-activity relationships of antcins for potential therapeutic applications.
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Background And Objectives: Developmental and epileptic encephalopathies (DEEs) are a group of neurological disorders characterized by early-onset seizures that are often resistant to treatment, by electroencephalographic abnormalities, and by developmental delay or regression. Their genetic basis remains largely unelucidated, especially in sub-Saharan Africa (SSA). We investigated the genetic bases of DEE in three Malian families.

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A novel electrochemical sensor for the detection of enrofloxacin (ENR) in aqueous solutions has been developed using a carbon paste electrode modified with a mixture of metal-organic frameworks (MOFs) of CuBTC and FeBTC. These MOFs were successfully synthesized via a solvothermal method and characterized using various techniques, including X-ray diffraction, Fourier-transform infrared spectroscopy, Brunauer-Emmett-Teller analysis, and X-ray photoelectron spectroscopy. The MOF mixture exhibited a particle size ranging from 40 to 100 nm, a high surface area of 1147 m/g, a pore volume of 0.

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Streamlining Linear Free Energy Relationships of Proteins through Dimensionality Analysis and Linear Modeling.

J Chem Inf Model

December 2024

Institute of Environmental Science and Engineering (IESE), School of Civil and Environmental Engineering (SCEE), National University of Sciences and Technology (NUST), H-12, Islamabad 44000, Pakistan.

Article Synopsis
  • Linear free energy relationships (LFERs) help predict how proteins interact with water, moving from simple models to a complex multi-parameter approach to improve accuracy.
  • A new two-parameter LFER model simplifies the process by focusing on octanol-water and air-water partition coefficients, providing strong predictive results for protein-water interactions.
  • This model shows comparable performance to traditional one-parameter models and offers a reliable alternative for estimating chemical behaviors when other descriptors are not accessible.
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The accurate prediction of particulate matter ( ) levels, an indicator of natural pollutants such as those resulting from dust storms, is crucial for public health and environmental planning. This study aims to provide accurate forecasts of over Morocco for 5 days. The analog ensemble (AnEn) and the bias correction (AnEnBc) techniques were employed to post-process forecasts produced by the Copernicus Atmosphere Monitoring Service (CAMS) global atmospheric composition forecasts, using CAMS reanalysis data as a reference.

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Employee-driven innovation (EDI) is still under-researched in health policy and system research, particularly in lowand middle-income countries. EDI is recognized as a lever to improve the commitment of health workers, promote quality of care, and contribute to creating value and transforming healthcare practices, services, structures, and processes. The mechanisms underlying the emergence of EDI processes and outcomes include core capabilities to cope with complexity, building spaces for learning, fostering sense-making and sense-giving, and collective problem-solving.

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Optimization of hydrogen production using a coculture of Chlamydomonas reinhardtii and activated sludge bacteria.

Chemosphere

December 2024

Department of Civil and Environmental Engineering and National Water and Energy Center, United Arab Emirates University, Al Ain, 15551, United Arab Emirates. Electronic address:

The production of biophotolytic hydrogen (H) relies on the effective management of oxygen (O) levels. Coculturing bacteria with microalgae helps mitigate the excess O produced by algal cells. After depleting O, the bacteria activate the enzyme hydrogenase in microalgae, leading to H production.

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The impact of HIV antiretroviral therapy on gut microbiota: the need for well-designed longitudinal studies.

J Infect Dev Ctries

October 2024

University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Introduction: Human immunodeficiency virus (HIV) infection remains a major public health concern despite a significant decline in HIV-related mortality and morbidity. These significant advances are linked mostly to effective antiretroviral therapy (ART). However, these treatments are not without consequences on other microorganisms in our body, especially when they must be used for life.

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Background: Botulinum neurotoxin serotypes E and F (BoNT/E and BoNT/F) produced by the bacteria Clostridium botulinum (C. botulinum) found in a wide variety of foods cause poisoning in humans with high mortality rates. Mouse bioassays (MBAs), the gold standard method for BoNT detection, have a low detection limit; however, require experienced personnel and take a long time to obtain results.

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With the development of internet technologies, it is now usual to communicate enormous amounts of text and visual data over networks, which calls for stringent procedures to guarantee confidentiality and integrity throughout transmission. An important part of safeguarding image communication over secure channel is cryptography. This study proposes an effective way to secure sensitive data by creating tamper-proof cryptosystems and authentication mechanisms.

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Green synthesis of starch/chitosan complex via ozone-mediated Schiff reaction: Structure, thermal behaviors and surface properties.

Int J Biol Macromol

January 2025

Key Laboratory for Deep Processing of Major Grain and Oil, Ministry of Education, Hubei Key Laboratory for Processing and Transformation of Agricultural Products, Wuhan Polytechnic University, Wuhan 430023, PR China; School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430023, PR China; Food Green Processing Technology and Intelligent Equipment Hubei Engineering Research Center, Wuhan Polytechnic University, Wuhan 430023, Hubei, PR China. Electronic address:

Ozone was used as a green and environmentally friendly initiator to directly induce a Schiff base cross-linking reaction between chitosan and waxy rice starch (CS) in the present investigation. The effects of oxidation on the structure of chitosan/starch bio-based composite, along with the cross-linked structure formation via Schiff base reaction, were investigated and confirmed using FTIR, XRD, and XPS characterization techniques. The formation of new bonds (C=N) along with other attributes imparted by the cross-linking reaction were evaluated and characterized.

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Background: To overcome the spread of high pyrethroid resistance in the main malaria vectors and malaria disease persistence, it is crucial to look for effective and better resistance management strategies. Understanding the phenotypic profile of against alternatives insecticides like organophosphates and carbamates is crucial.

Methods: larvae and pupae were collected from the breeding sites in rice fields, pineapple crop areas, and peri-urban areas.

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Hypoxia-inducible factor-1 (HIF-1) regulates cell growth, protein translation, metabolic pathways and therefore, has been advocated as a promising biological target for the therapeutic interventions against cancer. In general, hyperactivation of HIF-1 in cancer has been associated with increases in the expression of glucose transporter type-1 (GLUT-1) thus, enhancing glucose consumption and hyperactivating metabolic pathways. The collective behavior of GLUT-1 along with previously known key players AKT, OGT, and VEGF is not fully characterized and lacks clarity of how glucose uptake through this pathway (HIF-1) probes the cancer progression.

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Background: Genomic sequence similarity comparison is a crucial research area in bioinformatics. Multiple Sequence Alignment (MSA) is the basic technique used to identify regions of similarity between sequences, although MSA tools are widely used and highly accurate, they are often limited by computational complexity, and inaccuracies when handling highly divergent sequences, which leads to the development of alignment-free (AF) algorithms.

Results: This paper presents TreeWave, a novel AF approach based on frequency chaos game representation and discrete wavelet transform of sequences for phylogeny inference.

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Bitumen exhibits viscoelastic properties, showcasing both viscous and elastic behaviors, which are characterized by the phase angle and dynamic modulus. Issues like early fatigue fractures, rutting, and permanent deformations in bituminous asphalt pavements arise due to moisture susceptibility, high-temperature deformation, low-temperature cracking, and overloading. These distresses result in potholes, alligator cracks, and specific deformations that lead to early pavement failure, increasing rehabilitation and maintenance costs.

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