Enhancing Al-Air Battery Performance with Beta-d-Glucose and Adonite Additives: A Combined Electrochemical and Theoretical Study.

Al-air batteries are distinguished by their high theoretical energy density, yet their broader application is hindered by hydrogen evolution corrosion. This research focuses Beta (+) d-glucose (S1) and Adonite (S2) as potential corrosion inhibitors for the Al-5052 alloy within a 4 M NaOH solution. Utilizing electrochemical techniques, hydrogen evolution assessments, and surface analyses, our findings indicate enhancements in anode utilization by 21.

Personality traits and their correlation with behavior in the bonnet macaque (Macaca radiata) in southern India.

The purpose of our research was to identify the primary personality traits of bonnet macaques using an observer-based questionnaire and to assess the accuracy of this method in predicting behavior. Additionally, we examined the relationship between personality traits and variables such as sex, age, and rank. We rated 25 males and 38 females on 50 personality questionnaire items using a 7-point scale, with reliable ratings and good agreement among raters (the lowest of the calculated ICC (3:k) index ≥ 0.

Crystal structure, Hirshfeld surface analysis, and DFT and mol-ecular docking studies of 6-cyanona-phthalen-2-yl 4-(benz-yloxy)benzoate.

In the title compound, CHNO, the torsion angle associated with the phenyl benzoate group is -173.7 (2)° and that for the benz-yloxy group is -174.8 (2)° establishing an -type conformation.

Structural, morphological, mechanical, and electrical studies of N. nucifera fibres.

The Powder X-ray diffraction (PXRD) data of Nelumbo Nucifera fibre is utilized to study multifaceted properties. Rietveld refinement was carried out along with cellulose phase. The crystallite size was computed using the Scherrer equation, and through first principle calculations, it has been illustrated and concluded that the size is not ellipsoidal, as previously suggested by other researchers; rather, it exhibits a multidimensional shape.

Molecular dynamic studies of gold nanoparticles in a dental material TEGDMA.

Context: In the context of biomaterials, triethylene glycol dimethacrylate (TEGDMA) is a widely used monomer in dental resins due to its favorable mechanical properties and ease of polymerization. However, improving its structural stability and enhancing its performance in biological applications remain crucial goals. This study examines the impact of incorporating gold (Au) nanoparticles into the TEGDMA matrix, focusing on their potential to improve mechanical, thermal, and optical properties for biomedical applications.

Green synthesis of silver nanoparticles using leaf extracts: preparation, physicochemical characterization and ameliorative effect against human cancer cell lines.

Unlabelled: The present study to production of silver nanoparticles (AgNPs) by leaf extracts of and to evaluate the activity of anticancer by using AgNPs against cancer cell lines such as MCF-7, HEPG2, H9C2, HEK293 and H1975. The synthesized AgNPs were characterized by using UV-Vis spectroscopy, EDS, FT-IR, XRD, DLS, SEM and HRTEM with SAED patterns. The surface plasmon resonance (SPR) of AgNPs formed a peak centered at 427 nm by UV-Vis analysis.

TFF3 drives Hippo dependent EGFR-TKI resistance in lung adenocarcinoma.

Intrinsic and acquired resistance represent major obstacles to optimize outcomes in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) targeted therapy in lung adenocarcinoma (LUAD). Hence, a deeper understanding of EGFR-TKI resistance mechanisms in LUAD will potentially assist in formulating strategies to delay or overcome such resistance. Herein, it was observed that trefoil factor 3 (TFF3) is a crucial mediator of the LUAD EGFR-TKI response.

Decoding tumor microenvironment: EMT modulation in breast cancer metastasis and therapeutic resistance, and implications of novel immune checkpoint blockers.

Tumor microenvironment (TME) and epithelial-mesenchymal transition (EMT) play crucial roles in the initiation and progression of tumors. TME is composed of various cell types, such as immune cells, fibroblasts, and endothelial cells, as well as non-cellular components like extracellular matrix (ECM) proteins and soluble factors. These elements interact with tumor cells through a complex network of signaling pathways involving cytokines, growth factors, metabolites, and non-coding RNA-carrying exosomes.

Comparative Study of Non-invasive Mouse Models of Pancreatitis.

Background And Aims: Although a relevant animal model is essential for studying human diseases, one has yet to be established for mouse pancreatitis. Early non-invasive models of mouse pancreatitis have serious limitations.

Methods: In this study, we compared the efficiency, consistency, and reproducibility of inducing pancreatitis in 3 non-invasive mouse models of pancreatitis in Wistar albino mice: (1) L-arginine-induced model (2 intraperitoneal injections of 4 g/kg body weight of L-arginine spaced 1 h apart), (2) caerulein-induced model (6 intraperitoneal injections of 50 µg/kg body weight of caerulein at hourly intervals), and (3) caerulein + LPS (lipopolysaccharide)-induced model (6 intraperitoneal doses of 50 µg/kg body weight of caerulein at hourly intervals, along with an LPS [10 mg/kg body weight] injection immediately after the last caerulein injection).

Multifaceted growth promotion and biocontrol of Agroathelia rolfsii and induction of defense mechanism by Bacillus amyloliquefaciens SS-CR10 on chilli.

Plant-growth-promoting (PGP) endophytic bacteria are beneficial microorganisms that can help plants withstand biotic stress caused by fungal phytopathogens. In the present study, 78 endophytic bacterial isolates were isolated from chilli (Capsicum annuum L.).

Probing the hybridized triazole-chalcones: an in-depth investigations of molecular structure journey towards antibacterial potential against DNA gyrase.

The present study delves into the comprehensive structural investigations of the six Chalcone derivatives (), each featuring the 1, 2, 3 triazole linkages. The work commences with the synthesis by employing a multifaceted approach to unravel its molecular properties and potential biological significance. Single crystal X-ray diffraction technique was used to determine the precise 3D structure of the grown single crystals of and .

Exploring the association of dietary inflammatory index, disease progression and cellular integrity in chronic kidney disease: A cross-sectional study.

Background: While the anti-inflammatory effects of specific nutrients are well established, there is limited research on the relationship between overall dietary patterns and chronic kidney disease (CKD). Therefore, we aimed to assess the association between dietary inflammatory index (DII) scores and biochemical and body composition parameters in pre-dialysis CKD patients.

Methods: The DII scores of 143 pre-dialysis CKD subjects were calculated using 24-h recalls.

Correlation of Multiple Measures of Voice Evaluation Among Individuals with Muscle Tension Dysphonia: An Exploratory Study.

Primary Muscle Tension Dysphonia (MTD) occurs in the absence of structural or neurologic etiologies. Patients with MTD are frequently encountered in clinics and are evaluated using multiple measures of voice evaluation. Studies reporting on the correlation of multiple measures of voice evaluation among individuals with MTD are minimal, which led to this study.

Projected epidemiological trends and burden of liver cancer by 2040 based on GBD, CI5plus, and WHO data.

Incidence of liver cancer as one of the most common cancers worldwide and become the significant contributor for the mortality among cancer patients. The disease burden, risk factors, and trends in incidence and mortality of liver cancer globally was described subsequently estimated the projections of liver cancer incidence or mortality by 2040. Data regarding age-standardized incidence and mortality rates for liver cancer was obtained from multiple databases, including GLOBOCAN 2020, CI5 volumes I-XI, WHO mortality database, and Global Burden of Disease (GBD)-2019.

Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies.

Background: Hematopoiesis within the bone marrow (BM) is a complex and tightly regulated process predominantly influenced by immune factors. Aging, diabetes, and obesity are significant contributors to BM niche damage, which can alter hematopoiesis and lead to the development of clonal hematopoiesis of intermediate potential (CHIP). Genetic/epigenetic alterations during aging could influence BM niche reorganization for hematopoiesis or clonal hematopoiesis.

LC-MS/MS characterization of pirtobrutinib impurities and product degradation: stability studies.

This study examined the fragmentation, degradation pathways and DPs of pirtobrutinib, which have not been previously reported in the literature. The main goal of the current work is to develop, validate, and characterize forced degradation products using LC-MS/MS. An isocratic HPLC methodology was developed for the quantitative measurement of pirtobrutinib at a of 219 nm.

CRISPR: New promising biotechnological tool in wastewater treatment.

The increasing demand for water resources with increase in population has sparked interest in reusing produced water, especially in water-scarce regions. The clustered regularly interspaced short palindromic repeats (CRISPR) technology is an emerging genome editing tool that has the potential to trigger significant impact with broad application scope in wastewater treatment. We provide a comprehensive overview of the scope of CRISPR-Cas based tool for treating wastewater that may bring new scope in wastewater management in future in controlling harmful contaminants and pathogens.

Adsorption - Advanced oxidation process (AAOP) for the heavy metals and organic matter removal from leachate using combined filtration -Fenton's and Photo-Fenton's treatment.

Design of cost - effective filtration unit was carried out to evaluate the efficiency of different filter media made of locally available materials to treat raw leachate. Four different filter media laterites, peat, bagasse and a mixture of all were considered as study filter media for the removal of Zinc, Nickel, Copper and Lead from raw leachate. The reactor exhibited a significant removal efficiency when the three-filter media were combined as a combination.

Counteraction of unconjugated bilirubin against heme-induced toxicity in platelets.

Platelets are essential for normal hemostasis and thrombosis but become hyperactive in hemolytic disorders. Cell-free heme is known to be toxic to platelets and endothelial cells, playing a significant role in the progression of pathological complications in various hemolytic conditions. The abnormal activation of circulatory platelets results in micro/macrovascular thrombosis and clot formation in the lungs, worsening the disease.

Distinct chemical structures inhibit the CEMIP hyaluronidase and promote oligodendrocyte progenitor cell maturation.

Growing evidence supports pathogenic roles for chronically elevated hyaluronidase activity in numerous conditions. Elevated expression of one such hyaluronidase, the Cell Migration Inducing and hyaluronan binding Protein (CEMIP), has been implicated in the pathogenesis and progression of several cancers as well as demyelinating diseases in the central nervous system (CNS). Developing effective and selective CEMIP inhibitors could therefore have efficacy in treating a variety of conditions where CEMIP is chronically elevated.

Isoxazole based nucleosides induce autophagy through the production of ROS and the suppression of the β-catenin pathway in human colorectal carcinoma cells.

β-catenin is frequently implicated in signaling pathways that regulate autophagy, and the production of reactive oxygen species (ROS) has been linked to autophagy activation. Isoxazole-based nucleoside compounds have demonstrated anti-cancer properties. In this study, we report the identification of novel isoxazole-nucleosides as anti-tumor agents and their impact on autophagy in human colorectal carcinoma (CRC) cells.

Electrifying waste textiles: Transforming fabric scraps into high-performance triboelectric nanogenerators for biomechanical energy harvesting.

Textiles are an integral part of daily life globally, but their widespread use leads to significant waste generation. Repurposing these discarded fabrics for energy harvesting offers a sustainable solution to both energy demand and textile waste management. In this study, Textile-based Triboelectric Nanogenerators (T-TENGs) were developed using recycled cloth as tribopositive layers and polyvinyl chloride (PVC) film as the tribonegative layer, with aluminum foil tape serving as electrodes.