61 results match your criteria: "the affiliated Yiwu Hospital of Wenzhou Medical University[Affiliation]"

Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice.

Brain Res

July 2016

School of Environmental Science and Public Health, Wenzhou Medical University, 1210 University Town, Wenzhou, Zhejiang 325035, PR China.

Sodium butyrate (SB) has been widely used to treat cerebral diseases. The aim of the present study is to examine the neuroprotective effects of SB on early TBI in mice and to explore the underlying mechanisms of these effects. TBI was induced using a modified weight-drop method.

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Topical application of epidermal growth factor with no scaffold material on the healing of human traumatic tympanic membrane perforations.

Clin Otolaryngol

December 2016

Department of General Medicine, Wenzhou Medical University, Renji College, Zhejiang, 325035, China.

Objective: We evaluated the effects of conservative treatment and topical application of epidermal growth factor (EGF) with no scaffold material on the healing of human traumatic tympanic membrane perforations (TMPs).

Study Design: Prospective, randomised clinical trial.

Methods: A prospective analysis was performed between January 2015 and March 2015 for the treatment of human traumatic TMPs.

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Objective: The use of growth factors to achieve closure of human traumatic tympanic membrane perforations (TMPs) has recently been demonstrated. However, pretreatment factors affecting healing outcomes have seldom been discussed. The objective of this study was to evaluate pretreatment factors contributing to the success or failure of healing of TMPs using fibroblast growth factor-2 (FGF-2).

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Utility of basic fibroblast growth factor in the repair of blast-induced total or near-total tympanic membrane perforations: A pilot study.

Am J Otolaryngol

August 2016

Molecular Pharmacology Research Center, School of Pharmacy, Zhejiang Provincial Key Laboratory of Biotechnology Pharmaceutical Engineering, Wenzhou Medical University, Zhejiang, China. Electronic address:

Objective: A pilot study was performed to investigate the utility of basic fibroblast growth factor (bFGF) in the repair of blast-induced total or near-total tympanic membrane perforations (TMPs).

Study Design: Prospective clinical study.

Setting: Tertiary university hospital.

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The effect of ofloxacin otic drops on the regeneration of human traumatic tympanic membrane perforations.

Clin Otolaryngol

October 2016

Molecular Pharmacology Research Center, School of Pharmacy, Zhejiang Provincial Key Laboratory of Biotechnology Pharmaceutical Engineering, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Objective: To investigate the effects of direct application of ofloxacin otic drops on human traumatic tympanic membrane perforations (TMPs).

Study Design: Prospective, sequential allocation, controlled clinical study.

Setting: Tertiary university hospital.

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Objectives/hypothesis: We evaluated the effects of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on the healing of large traumatic tympanic membrane perforations (TMPs).

Study Design: Prospective clinical study.

Setting: Tertiary university hospital.

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