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Reticular Pseudodrusen on the Risk of Progression in Intermediate Age-Related Macular Degeneration.
Am J Ophthalmol
July 2022
Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital (Z.W., H.K., L.A.B.H., R.H.G.), East Melbourne, Australia; Ophthalmology, Department of Surgery, the University of Melbourne (Z.W., H.K., R.H.G.), Melbourne, Victoria, Australia.
Purpose: To examine the association between reticular pseudodrusen (RPD) and progression to late age-related macular degeneration (AMD) in individuals with intermediate AMD.
Design: Prospective cohort study.
Methods: Two hundred eighty eyes from 140 participants with bilateral large drusen underwent multimodal imaging (MMI), including optical coherence tomography (OCT), near-infrared reflectance (NIR), fundus autofluorescence, and color fundus photography (CFP), at 6-monthly intervals up over a 36-month follow-up period.