1 results match your criteria: "the University of Manchester and Manchester Cancer Research Center[Affiliation]"
Imidazoacridin-6-ones as novel inhibitors of the quinone oxidoreductase NQO2.
Bioorg Med Chem Lett
May 2010
School of Pharmacy and Pharmaceutical Sciences, the University of Manchester and Manchester Cancer Research Center, Oxford Road, Manchester M13 9PT, UK.
The purpose of the work was to identify novel inhibitors of the enzyme NQO2. Using computational molecular modelling, a QSAR (R(2)=0.88) was established, relating inhibitory potency with calculated binding affinity.
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