770 results match your criteria: "the University of Leeds[Affiliation]"

Clove (, L.) is a rich source of polyphenols and antioxidants, but its intense flavor, poor solubility, and instability may limit its widespread and efficient use in industrial applications. In a series of laboratory-scale experiments, gum Arabic (GA) and maltodextrin (MD) were used as coating agents in various proportions (ranging from 0MD:100GA to 100MD:0GA) for encapsulation of clove extract using a freeze-drying method.

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The growth of boars may be inhibited because of aggressive and/or sexual activity. Dietary Br, Mg and tryptophan (Trp) as well as immunocastration may reduce these behaviours. In Experiment 1, 200 boars and 40 barrows were allocated to six groups of four pens of 10 pigs per treatment.

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The climate change-associated abnormal weather patterns negatively influences the productivity and performance of farm animals. Heat stress is the major detrimental factor hampering production, causing substantial economic loss to the livestock industry. Therefore, it is important to identify heat-tolerant breeds that can survive and produce optimally in any given environment.

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The aim of this investigation was to comparatively assess the antioxidant and polyphenol compounds in fresh moringa pods sourced from two different regions in Australia, namely Queensland (QLD) and Western Australia (WAU). Total polyphenol content varied between 1.64 and 5.

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In a hyperconnected world, framing and managing biological invasions poses complex and contentious challenges, affecting socioeconomic and environmental sectors. This complexity distinguishes the field and fuels polarized debates. In the present article, we synthesize four contentious issues in invasion science that are rarely addressed together: vocabulary usage, the potential benefits of nonnative species, perceptions shifting because of global change, and rewilding practices and biological invasions.

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Background: Approximately 40% of older women in the community report experiencing urinary incontinence (UI); prevalence within secondary care is unknown. Illness, comorbidities, and hospital environments are likely to lead to higher prevalence.

Objectives: This study aimed to establish UI prevalence in older women admitted to hospitals and understand the views and knowledge of ward nurses in relation to older women's UI.

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A Teacher Prayer.

J Christ Nurs

December 2024

Dr. Fotarisman Zaluchu, is a senior lecturer in the Social Anthropology Department at Universitas Sumatera Utara. He completed his MPH at the University of Leeds in the field of International Health and earned his PhD from the University of Amsterdam in Anthropology. He is currently conducting research on gender, stunting, and health issues in the Indonesian region. His teaching expertise lies in health anthropology for medical, nursing, and anthropology students, as well as gender anthropology. He has been actively involved in missions targeting the younger generation through the IFES movement as a volunteer. Additionally, he has written Christian books on leadership and spiritual life.

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The livestock sector, essential for maintaining food supply and security, encounters numerous obstacles as a result of climate change. Rising global populations exacerbate competition for natural resources, affecting feed quality and availability, heightening livestock disease risks, increasing heat stress, and contributing to biodiversity loss. Although various management and dietary interventions exist to alleviate these impacts, they often offer only short-lived solutions.

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Anterior cruciate ligament (ACL) injuries result in abnormal knee motion and long-term joint degradation. ACL reconstruction (ACLR) is done with the aim of restoring normal knee kinematics and slowing the joint degradation process. It does appear that this inevitably happens and can be impacted by a multitude of factors.

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A suboptimal intrauterine environment during gestation may result in the programming of long-lasting structural and physiological alterations in the developing fetus, leading to health and production complications in adulthood. This observational study aimed to identify the impact of exposure to the summer season at different trimesters of gestation, dam parity, and their interaction on the postpartum disease incidence, first-lactation milk production, and herd lifespan of the offspring (F generation). Using a dataset collected from two commercial herds, the female offspring were categorized into three groups based on the trimester their dams experienced summer season during pregnancy: (1) first trimester (n = 2345), (2) second trimester (n = 3513), and (3) final trimester (n = 4988).

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There have been repeated calls to train conservationists capable of transcending disciplinary boundaries. However, little empirical work has been done to document conservation teaching. We investigate the content taught in conservation higher education across the United Kingdom and Australia.

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UK physiotherapists' perceptions on providing face-to-face and virtual rehabilitation for patients with Greater Trochanteric Pain Syndrome (GTPS): A cross-sectional survey.

Musculoskelet Sci Pract

November 2024

Leeds Institute of Rheumatic and Musculoskeletal Medicine, The University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Chapel Allerton Hospital, Chapeltown Rd, Leeds, LS7 4SA, UK. Electronic address: https://twitter.com/ProfTonyRedmond.

Background: Greater Trochanteric Pain Syndrome (GTPS) is a prevalent and debilitating cause of lateral hip pain. Physiotherapists often prescribe exercises and educate patients on self-management strategies. Virtual consultations have increased since COVID-19.

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Article Synopsis
  • Despite advancements in treatment, ischaemic heart disease remains the top cause of illness and death among women, with many being underdiagnosed and undertreated.
  • Women face unique risk factors that increase their cardiovascular risk, necessitating a tailored approach in healthcare that includes both traditional and female-specific considerations.
  • The British Cardiovascular Society aims to highlight sex-related differences in CVD management, proposing solutions to improve access to diagnosis and treatment for women and encouraging further research on gender disparities in cardiovascular health.
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mutations are the major cause of Meckel-Gruber syndrome. TMEM67 is involved in both ciliary transition zone assembly, and non-canonical Wnt signaling mediated by its extracellular domain. How TMEM67 performs these two separate functions is not known.

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Beyond sensory quality, food-evoked emotions play a crucial role in consumers acceptance and willingness to try, which are essential for product development. The link between fermented coffee sensory characteristics and elicited emotional responses from consumers is underexplored. This study aimed to evaluate consumers' acceptability of spontaneously fermented and unfermented roasted coffee through self-reported sensory evaluation and biometrics assessment.

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Distinct, common and synergistic effects of insulin and IGF-1 receptors on healthy murine ageing.

Heliyon

August 2024

Leeds Institute of Cardiovascular and Metabolic Medicine, LIGHT Laboratories, The University of Leeds, Clarendon Way, Leeds, LS2 9JT, United Kingdom.

Objective: Reduced IGF-1 signalling is an evolutionarily conserved mediator of longevity, yet the magnitude of this effect is substantially larger in organisms retaining a common insulin and IGF-1 receptor. Whether this reflects the failure to simultaneously reduce IGF-1 and insulin signalling in mammalian model systems remains unexplored, as is the associated impact on markers of healthy ageing. We set out to address these uncertainties.

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Article Synopsis
  • In 2018, the World Endoscopy Organization (WEO) established standardized methods to calculate post-colonoscopy colorectal cancer rates over three years (PCCRC-3yr), prompting a systematic review to assess global rates and associated risk factors.
  • The review analyzed studies from five databases and included eight studies totaling over 220,000 colorectal cancer cases, finding a pooled PCCRC-3yr rate of 7.5% that significantly decreased from 7.9% in 2006 to 6.7% in 2012.
  • Higher PCCRC rates were linked to specific risk factors, including inflammatory bowel disease, prior colorectal cancer, proximal cancer location, diverticular disease, and being female, undersc
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Plants are an immense source of drugs, and 50% of modern pharmacopeia has a plant origin. With increasing life expectancy in humans, many age-related degenerative diseases converge on oxidative cellular stress pathways. This provides an opportunity to develop broad treatments by targeting the cause of common pathologic cell degeneration.

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Aims: Diabetes mellitus (DM) increases heart failure incidence and worsens prognosis, but its molecular basis is poorly defined in humans. We aimed to define the diabetic myocardial transcriptome and validate hits in their circulating protein form to define disease mechanisms and biomarkers.

Methods And Results: RNA-sequencing data from the Genotype-Tissue Expression (GTEx) project was used to define differentially expressed genes (DEGs) in right atrial (RA) and left ventricular (LV) myocardium from people with vs.

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Betaine supplementation in dairy cattle has gained attention due to its potential benefits to production and health as a methyl donor, which can play a crucial role in the metabolism of dairy cows. The objective of the current meta-analysis was to quantify the effects of betaine supplementation on milk production, composition, β-hydroxybutyric acid (BHBA), and non-esterified fatty acids (NEFA). A systematic literature search was carried out, all relevant studies were retrieved, and the meta-analysis was carried out.

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Article Synopsis
  • Betaine supplementation boosts growth and health in monogastric animals, with mixed results in ruminants; this analysis focuses on ruminant outcomes.
  • A thorough review of studies revealed that betaine significantly raises milk yield, dry matter intake, and milk lactose in dairy cows, even under heat stress.
  • In small ruminants and beef cattle, betaine also enhances liveweight, daily gain, and carcass weight, indicating its potential benefits across different livestock types.
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Exploring Prior Antibiotic Exposure Characteristics for COVID-19 Hospital Admission Patients: OpenSAFELY.

Antibiotics (Basel)

June 2024

Centre for Health Informatics, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, UK.

Previous studies have demonstrated the association between antibiotic use and severe COVID-19 outcomes. This study aimed to explore detailed antibiotic exposure characteristics among COVID-19 patients. Using the OpenSAFELY platform, which integrates extensive health data and covers 40% of the population in England, the study analysed 3.

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