5 results match your criteria: "the University of Australia[Affiliation]"
Tumour Dissemination in Multiple Myeloma Disease Progression and Relapse: A Potential Therapeutic Target in High-Risk Myeloma.
Cancers (Basel)
December 2020
Myeloma Research Laboratory, Faculty of Health and Medical Sciences, Adelaide Medical School, The University of Australia, Adelaide 5005, Australia.
Multiple myeloma (MM) is a plasma cell (PC) malignancy characterised by the presence of MM PCs at multiple sites throughout the bone marrow. Increased numbers of peripheral blood MM PCs are associated with rapid disease progression, shorter time to relapse and are a feature of advanced disease. In this review, the current understanding of the process of MM PC dissemination and the extrinsic and intrinsic factors potentially driving it are addressed through analysis of patient-derived MM PCs and MM cell lines as well as mouse models of homing and dissemination.
View Article and Find Full Text PDFEffect of halides on the solvation of poly(ethylene oxide) in the ionic liquid propylammonium nitrate.
J Colloid Interface Sci
January 2019
Priority Research Centre for Particle Processing and Transport, Newcastle Institute for Energy and Resources, The University of Australia, NSW 2308, Australia. Electronic address:
Hypothesis: The solvation characteristics of poly(ethylene oxide) (PEO) in nanostructured protic ionic liquids (PILs) are driven by polymer-solvent interactions in the polar domains of the PIL. This work hypothesises that the nanostructure of a PIL can be altered via halide addition, directly affecting the solvation of PEO.
Experiments: Small angle neutron scattering (SANS) is used to explore the conformation of 38 kDa PEO dissolved in the PIL propylammonium nitrate (PAN), a mol fraction of 10% propylammonium chloride (PACl) in PAN, and a mole fraction of 10% propylammonium bromide (PABr) in PAN.
An Exploration of the Use of Eye Gaze and Gestures in Females With Rett Syndrome.
J Speech Lang Hear Res
December 2016
Telethon Kids Institute, The University of Australia, Perth, Western Australia.
Purpose: This study investigated the communicative use of eye gaze and gestures in females with Rett syndrome.
Method: Data on 151 females with Rett syndrome participating in the Australian Rett Syndrome Database was used in this study. Items from the Communication and Symbolic Behavior Scales Developmental Profile Infant-Toddler Checklist (Wetherby & Prizant, 2002) were used to measure communication.
Hydrocortisone prevents immunosuppression by interleukin-10+ natural killer cells after trauma-hemorrhage.
Crit Care Med
December 2014
1Faculty of Medicine, UPRES EA 3826, Thérapeutiques Cliniques et Expérimentales des Infections, University of Nantes, Nantes, France. 2Intensive Care Unit, Anesthesia and Critical Care Department, Hôtel Dieu-HME, University Hospital of Nantes, Nantes, France. 3Biochemistry Department, Hôtel Dieu-University Hospital of Nantes, Nantes, France. 4UMR PhAN 1280, Institut des Maladies de L'Appareil Digestif, University Hospital of Nantes, Nantes, France. 5CHU Nantes, Laboratoire d'Immunologie, Centre d'Immunomonitorage Nantes Atlantique (CIMNA), Nantes, France. 6INSERM Center of Research in Transplantation and Immunology UMR 1064, Nantes, France. 7INSERM, Unité 892, Institut de Recherche Thérapeutique, Université de Nantes, Nantes, France. 8Etablissement Français du Sang, Université de Nantes, Immunovirologie et Polymorphisme Génétique, Nantes, France. 9Department of Microbiology and Immunology [at the Doherty Institute of Infection and Immunity], The University of Australia, Parkville, Victoria, Australia. 10Department of Biochemistry and Molecular Biology at the Bio21 Institute, The University of Melbourne, Parkville, Victoria, Australia.
Objective: Trauma induces a state of immunosuppression, which is responsible for the development of nosocomial infections. Hydrocortisone reduces the rate of pneumonia in patients with trauma. Because alterations of dendritic cells and natural killer cells play a central role in trauma-induced immunosuppression, we investigated whether hydrocortisone modulates the dendritic cell/natural killer cell cross talk in the context of posttraumatic pneumonia.
View Article and Find Full Text PDFCharacteristics of patients with acute low back pain presenting to primary care in Australia.
Clin J Pain
January 2009
The George Institute of International Health, the University of Australia, Australia.
Objectives: This study aimed to provide a comprehensive profile of a representative sample of patients with acute low back pain drawn from the primary care setting. A secondary aim was to determine whether patient characteristics are associated with pain intensity or disability at the initial consultation.
Methods: A total of 1172 consecutive patients with acute low back pain presenting to clinics of primary care practitioners (general practitioners, physiotherapists, and chiropractors) in Australia were recruited.