6 results match your criteria: "the Union Hospital Affiliated to Fujian Medical University[Affiliation]"
Rare, low-frequency and common coding variants of ARHGEF28 gene and their association with sporadic amyotrophic lateral sclerosis.
Neurobiol Aging
March 2020
Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China; National Clinical Research Center for Geriatric Diseases, Beijing, China. Electronic address:
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Over 90% of cases are sporadic (sALS) and 5%-10% are familial (fALS). So far, more than 20 genes/loci have been linked to ALS.
View Article and Find Full Text PDF[Clinicopathologic analysis of a series of intraventricular meningioma].
Zhonghua Bing Li Xue Za Zhi
February 2019
Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
[Effects of triptolide on the apoptosis and H3K4 protein methylation in multiple myeloma cells].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
May 2017
Department of Hematology, The People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou 350004.
Objective: To investigate the effects of triptolide (Chinese Traditional Medicine)on the apoptosis and H3K4 protein methylation in multiple myeloma cells.
Methods: The RPMI8226 cells were cultured with different concentrations(10,20,40,80 and 160 nmol/L)of triptolide for different incubation time (24 h,48 h and 72 h). The inhibition of triptolide on RPMI8226 cell proliferation was detected by MTT assay.
[The effect of valsartan on the expression of the receptor for advanced glycation end products in human glomerular mesangial cells].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
August 2011
Department of Endocrinology, The Union Hospital Affiliated to Fujian Medical University, Fujian Institute of Endocrinology, Fuzhou 350001, China.
Objective: To elucidate the effect of valsartan on human glomerular mesangial cells oxidative stress and the expression of the receptor for advanced glycation end products (RAGE) induced by the advanced glycation end-products (AGEs).
Methods: Human glomerular mesangial cells were treated with advanced glycation end-product-bovine serum albumin (AGE-BSA) in the presence of valsartan. The reactive oxygen species (ROS) in cells were measured by Flow cytometry, and the mRNA of p47 phox, which was the primary subunits of NADPH oxidase, was detected by semi-quantitative reberse transcription polymerase chain reaction (RT-PCR).
[Effects of hyperbaric oxygen on synaptic ultrastructure and synaptophysin expression in hippocampus of neonatal rats with hypoxic-ischemic brain damage].
Zhonghua Er Ke Za Zhi
March 2010
Pediatric Department, the Union Hospital Affiliated to Fujian Medical University, Fuzhou 350001, China.
Objective: To observe the effects of hyperbaric oxygen (HBO) on synaptic ultrastructure and the synaptophysin expression (p38) in hippocampal CA3 after hypoxia-ischemic brain damage (HIBD) in neonatal rats.
Methods: The rat model of HIBD was made by the method of Bjelke and divided randomly into two groups (n = 10)--HIBD group and HBO-treated HIBD group. Another 20 rats underwent sham-operation and were also divided randomly into HBO-treated control group and the control group.
[Effect of berberin hydrochloride on blood concentration of cyclosporine A in cardiac transplanted recipients].
Zhongguo Zhong Xi Yi Jie He Za Zhi
August 2008
Department of Cardiovascular Surgery, The Union Hospital Affiliated to Fujian Medical University, Fuzhou 350001.
Objective: To observe the clinic effect of combined use of berberin hydrochloride (Ber) with cyclosporine A (CsA) on the blood concentration of CsA in heart transplanted recipients.
Methods: The blood concentration of CsA, liver-renal function and blood lipids in 22 heart transplanted recipients, who received Ber-CsA combined therapy, were measured.
Results: The whole blood steady state concentration of CsA, C0 and C2, in recipients after being treated with Ber-CsA significantly increased than those before applying Ber-CsA (P < 0.