3,360 results match your criteria: "the Third Affiliated Hospital of Soochow University[Affiliation]"
Diagn Pathol
August 2024
Department of Pathology, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, Jiangsu, P.R. China.
Aims: Compared to primary breast sarcoma (BSs), radiotherapy-induced sarcoma (RIS) is a less frequent type of secondary breast sarcoma. Undifferentiated pleomorphic sarcoma (UPS) is an even rarer occurrence within the RIS category. This study aimed to present the clinicopathologic and molecular features of breast radiotherapy-induced UPS.
View Article and Find Full Text PDFAnn Surg Treat Res
August 2024
Department of General Surgery, the Second Affiliated Hospital of Soochow University, Suzhou, China.
Purpose: This study was performed to investigate influencing factors of preoperative muscle mass-to-fat ratio (MMFR) and its impact on overall survival and postoperative complications of colon cancer.
Methods: Patients who underwent colectomy for stage I-III colon cancer at the Second Affiliated Hospital of Soochow University between January 2016 and December 2022 were included. The skeletal muscle and fat area at the third lumbar vertebra were measured with preoperative CT measurement.
Aging Cell
October 2024
State Key Laboratory of Cardiovascular Diseases, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhonghua Xue Ye Xue Za Zhi
June 2024
Department of hematology, Dushu Lake Hospital Affiliated to Soochow University, Suzhou 215028, China National Clinical Medical Research Center of Blood Diseases, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou 215007, China Key Laboratory of Thrombosis & Hemostasis of National Health Commission of People's Republic of China, Suzhou 215006, China.
A 28-year-old woman was found to have coagulation factor Ⅷ activity (FⅧ∶C) <1% and von Willebrand factor antigen (VWF∶Ag) <1% during routine prenatal examinations. No pathogenic variation was found in the exon region of the VWF gene using next-generation sequencing. The clinical presentation of this patient does not match the clinical characteristics of type Ⅲ hemophilia [von Willebrand disease (VWD) ]; therefore, third-generation sequencing technology was used to perform whole-genome sequencing on the patient and her family members.
View Article and Find Full Text PDFInt J Gen Med
August 2024
Department of Urology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, 213000, People's Republic of China.
Turk J Gastroenterol
May 2024
Department of Gastroenterology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Background/aims: The endoscopic features of small-bowel gastrointestinal stromal tumors (GISTs) are not well defined. The objective of this study was to describe the endoscopic features of GISTs of the small intestine detected via single-balloon enteroscopy (SBE).
Materials And Methods: Patients with surgically confirmed small intestinal GISTs from January 2014 to September 2022 were retrospectively analyzed.
BMC Anesthesiol
August 2024
Department of Anesthesiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, 10032, China.
Background: This study compares the effect of positive end-expiratory pressure (PEEP) on postoperative pulmonary complications (PPCs) in patients with obesity undergoing laparoscopic bariatric surgery (LBS) under general anesthesia with mechanical ventilation.
Methods: A comprehensive search was conducted in PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials, China National Knowledge Internet, Wanfang database, and Google Scholar for studies published up to July 29, 2023, without time or language restrictions. The search terms included "PEEP," "laparoscopic," and "bariatric surgery.
BMJ Open
August 2024
Department of Nursing, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Mod Rheumatol
August 2024
Department of Rheumatology and Immunology, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Clin Cosmet Investig Dermatol
August 2024
Department of Dermatology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, People's Republic of China.
Neurology
September 2024
From the Department of Neurology (Z.Z., X.L., W.Z.), Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University; Department of Neurology (M.W.), The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Jiangsu, China; and Department of Epidemiology and Biostatistics (D.G.), School of Public Health, St Mary's Hospital, Imperial College London, United Kingdom.
Background And Objectives: Anxiety and depression have implications for ischemic stroke recovery. This study explored the association of genetically predicted anxiety and depression with functional outcome after ischemic stroke using Mendelian randomization (MR) approach.
Methods: Independent genetic variants associated with anxiety and depression at genome-wide significance level ( < 5 × 10) were obtained from large-scale genome-wide association studies (N = 1,306,354).
Int J Cardiol
November 2024
Department of Cardiology, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, Jiangsu Province, China. Electronic address:
Cancer Immunol Immunother
August 2024
Department of Tumor Biological Treatment, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, Jiangsu, China.
Background: HHLA2 (human endogenous retrovirus-H long terminal repeat-associating protein 2) represents a recently identified member of the B7 immune checkpoint family, characterized by limited expression in normal tissues but notable overexpression in various cancer types. Nevertheless, the precise function and interaction with immune cells remain poorly understood, particularly in laryngeal squamous cell carcinoma (LSCC). This investigation endeavored to elucidate the biological significance of HHLA2 within the tumor microenvironment of human LSCC tissues and delineate the clinical relevance and functional roles of HHLA2 in LSCC pathogenesis.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
August 2024
Department of Articular Orthopedics, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Transl Androl Urol
July 2024
Department of Urology, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Suzhou, China.
Background: Bladder cancer is a common malignancy with high invasion and poor clinical outcome. Intratumor heterogeneity (ITH) is linked to cancer progression and metastasis and high ITH can accelerate tumor evolution. Our objective is to develop an ITH-related signature (IRS) for predicting clinical outcome and immunotherapy benefit in bladder cancer.
View Article and Find Full Text PDFHeliyon
July 2024
Department of Urology, The Third Affiliated Hospital of Soochow University, 185 Juqian Street, Changzhou, 213003, Jiangsu, PR China.
Infect Drug Resist
July 2024
Department of Dermatology, The Second Affiliated Hospital of Wannan Medical College, Wuhu, People's Republic of China.
Asian J Surg
August 2024
Department of Urology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, China. Electronic address:
Medicine (Baltimore)
August 2024
Department of Emergency, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.
Rationale: Timely treatment and recovery of cardiac arrest in out-of-hospital settings present significant challenges. This report describes a novel method of integrating advanced monitoring techniques such as radial artery cannulation in the treatment of an 85-year-old male patient who suffered an out-of-hospital cardiac arrest (OHCA).
Patient Concerns: The patient, an 85-year-old man, experienced sudden cardiac arrest at home around 4:10 pm on November 22, 2023, characterized by immediate loss of consciousness and absence of pulse, and no response when called by name, necessitating urgent medical intervention.
Front Pharmacol
July 2024
Department of Cardiovascular Medicine, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, China.
Much research describes gut microbiota in atherosclerotic cardiovascular diseases (ASCVD) for that the composition of the intestinal microbiome or its metabolites can directly participate in the development of endothelial dysfunction, atherosclerosis and its adverse complications. Salidroside, a natural phenylpropane glycoside, exhibits promising biological activity against the progression of ASCVD. Recent studies suggested that the gut microbiota played a crucial role in mediating the diverse beneficial effects of salidroside on health.
View Article and Find Full Text PDFIntensive Care Med
August 2024
Interdepartmental Division of Critical Care Medicine, Departments of Medicine, Surgery, and Biomedical Engineering, University of Toronto, Toronto, Canada.
Purpose: Awake prone positioning has been reported to reduce endotracheal intubation in patients with coronavirus disease 2019 (COVID-19)-related acute hypoxemic respiratory failure (AHRF). However, it is still unclear whether using the awake prone positioning for longer periods can further improve outcomes.
Methods: In this randomized, open-label clinical trial conducted at 12 hospitals in China, non-intubated patients with COVID-19-related AHRF were randomly assigned to prolonged awake prone positioning (target > 12 h daily for 7 days) or standard care with a shorter period of awake prone positioning.
Cell Prolif
December 2024
Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Ischemic heart disease (IHD) is a prevalent cardiovascular condition that remains the primary cause of death due to its adverse ventricular remodelling and pathological changes in end-stage heart failure. As a complex pathologic condition, it involves intricate regulatory processes at the cellular and molecular levels. The immune system and cardiovascular system are closely interconnected, with immune cells playing a crucial role in maintaining cardiac health and influencing disease progression.
View Article and Find Full Text PDFAdv Ther
September 2024
Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Clin Neurophysiol
October 2024
Suzhou Guangji Hospital, The Affiliated Guangji Hospital of Soochow University, Suzhou, China. Electronic address:
Objective: This study aimed to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in chronic schizophrenia patients with tardive dyskinesia (TD) who were long-term hospitalized.
Methods: Sixty-four inpatients who met the DSM-IV diagnostic criteria for schizophrenia and TD were randomly assigned to either the active (N=35) or sham (N=29) group. Treatment was given 15 times, with each session lasting for 30 min, and an intensity of 2 mA.
J Biochem Mol Toxicol
August 2024
Department of Urology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu Province, China.
Recently, ezetimibe (EZM) has been suggested to be a potent Nrf2 activator that is important for preventing oxidative stress. Interestingly, we found that its metabolite ezetimibe ketone (EZM-K) also has antioxidant effects. Thus, we investigated the role of EZM-K in preventing renal ischemia‒reperfusion injury (RIRI).
View Article and Find Full Text PDF