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Clinical significance of HDAC9 in hepatocellular carcinoma.

Cell Mol Biol (Noisy-le-grand)

April 2019

Department of Hepatobiliary Surgery, the Second People's Hospital of Wuhu. No. 259, Jiuhua Middle Road, 241001 Wuhu City, Anhui Province, China.

In recent years, most related studies have found that chronic hepatitis B virus infection is the main cause of hepatocellular carcinoma (HCC), but the specific pathogenesis is still unclear. To investigate the function of HDAC in hepatocellular carcinoma (HCC), this study used qRT-PCR to determine the expression levels of miR-376a and HDAC9 mNRA in HCC and para-cancerous tissues. The clinical significance of HDAC9 in HCC was assessed in a study cohort containing 37 patients with HCC using immunohistochemistry.

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