1 results match your criteria: "the Second People's Hospital of Haibei Prefecture[Affiliation]"
Alisol B 23-acetate promotes white adipose tissue browning to mitigate high-fat diet-induced obesity by regulating mTOR-SREBP1 signaling.
J Integr Med
January 2024
Department of Geriatrics, the First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital), Jinan 250014, Shandong Province, China; Department of Traditional Chinese Medicine, the Second People's Hospital of Haibei Prefecture, Zangzu Autonomous Prefecture of Haibei, 810300, Qinghai Province, China. Electronic address:
Article Synopsis
- The study investigates the potential of alisol B 23-acetate (AB23A) as a treatment for obesity by promoting white adipose tissue (WAT) browning and improving metabolic health in mice on a high-fat diet.
- Experiments showed that AB23A reduced body weight, adipose tissue mass, improved glucose and insulin metabolism, and promoted energy expenditure without affecting food intake or physical activity.
- Findings suggest that AB23A might be a low-risk alternative for obesity management by targeting lipid distribution and metabolic profiles.