8 results match your criteria: "the Second Clinical Medical School of Southern Medical University[Affiliation]"

Rationale: Fetal skeletal anomalies are one of the most common and potentially pathogenic developmental abnormalities detected by ultrasound screening. Any suspected fetal skeletal dysplasias often require further comprehensive evaluations.

Patient Concerns: Here 4 families with adverse fetal skeletal system histories were enrolled, including their histories of gestation, childbirth, familial skeletal abnormalities, and pregnancy outcomes.

View Article and Find Full Text PDF

Antibiotic-Impregnated Calcium Sulfate vs. Wound Irrigation-Suction to Treat Chronic Calcaneal Osteomyelitis.

Foot Ankle Int

March 2022

Department of Orthopedics and Traumatology, Guangdong Second Provincial General Hospital, the Second Clinical Medical School of Southern Medical University, 466 Xingang Road C., Haizhu District, Guangzhou, 510317, China.

Background: Chronic osteomyelitis of calcaneus is not rare but is very hard to treat. Irrigation-suction and antibiotic-impregnated calcium sulfate following debridement are commonly used in managing chronic osteomyelitis, but their effects have rarely been compared. We aimed to compare the effectiveness of antibiotic-impregnated calcium sulfate with irrigation-suction in the treatment of patients with chronic calcaneal osteomyelitis.

View Article and Find Full Text PDF

Culture-negative chronic hematogenous osteomyelitis in a two months old girl: a case report.

BMC Musculoskelet Disord

August 2021

Department of Orthopaedics and Traumatology, Southern Medical University Nanfang Hospital, No. 1838, Guangzhou Ave. North, Guangzhou, Guangdong, 510515, People's Republic of China.

Background: Previous articles have focused on the diagnosis and treatment of acute hematogenous osteomyelitis. Here, we present a case of chronic hematogenous osteomyelitis in a 2-month-old girl. The diagnostic procedure was unusual and difficult due to negative culture results.

View Article and Find Full Text PDF

Background: The incidence of intramedullary infection is increasing with increased use of intramedullary fixation for long bone fractures. However, appropriate treatment for infection after intramedullary nailing is unclear. The purpose of this study was to report the results of our treatment protocol for infection after intramedullary nailing: intramedullary nail removal, local debridement, reaming and irrigation, and antibiotic-loaded calcium sulfate implantation with or without segmental bone resection and distraction osteogenesis.

View Article and Find Full Text PDF

The aim of the study was to research the biological functions of circRNA (hsa_circ_0079662) and its underlying mechanism in colorectal cancer. Drug-resistant cell lines (HT29-LOHP, HCT116-LOHP, HCT8-LOHP) were separately dealt with oxaliplatin concentration gradient (0.1-10 μmol/L).

View Article and Find Full Text PDF
Article Synopsis
  • - The study compared the effectiveness of antibiotic-loaded calcium sulphate versus wound irrigation-suction in treating lower limb chronic osteomyelitis in adult patients from January 2011 to July 2015.
  • - Results showed that the calcium sulphate group had a significantly higher success rate in the initial operation (90.74%) compared to the irrigation group (45%), despite facing more post-surgery incision leaks.
  • - Overall, antibiotic-loaded calcium sulphate reduced infection rates and complications, and led to shorter hospital stays and less need for systemic antibiotics compared to the irrigation method.
View Article and Find Full Text PDF

Background And Aim: Recent epidemiological studies indicated that metformin might improve the survival of various cancers. However, its benefit on pancreatic cancer was controversial.

Methods: We performed this meta-analysis to investigate the benefit of metformin on pancreatic cancer.

View Article and Find Full Text PDF