6 results match your criteria: "the Second Affiliated Hospital (Tangdu Hospital) of Air Force Medical University[Affiliation]"
A multifactorial risk scoring system for the prediction of early relapse in CMML patients with allo-HSCT: a nationwide representative multicenter study.
Bone Marrow Transplant
November 2024
Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Article Synopsis
- Chronic myelomonocytic leukemia (CMML) is a type of blood cancer where allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the only curative treatment, although not suitable for all patients, and relapse is a common issue.
- A nationwide study analyzed data from 238 CMML patients who underwent allo-HSCT across 27 medical centers and 307 patients from a research database to establish a risk scoring system to predict early relapse based on certain prognostic factors.
- Four key factors were identified that significantly increased the risk of relapse: bone marrow blasts over 10%, age greater than 60 years, low hemoglobin levels, and specific gene mutations, leading to a scoring system that categor
Electromagnetic navigation bronchoscopy-guided preoperative lung nodule localization in video-assisted thoracic surgery (VATS): a learning curve analysis.
Transl Lung Cancer Res
October 2024
Department of Thoracic Surgery, The Second Affiliated Hospital (Tangdu Hospital) of Air Force Medical University, Xi'an, China.
Article Synopsis
- - The study investigates the learning curve of electromagnetic navigation bronchoscopy (ENB) for marking small peripheral pulmonary nodules (PPNs) during video-assisted thoracic surgery, analyzing data from 300 patients under one endoscopist from 2019 to 2021.
- - Three learning phases were identified: Phase I (first 16 nodules), Phase II (17 to 107 nodules), and Phase III (107 to 300 nodules), with no significant differences in success rates across phases but variations in localization distances to pleura.
- - The research also found different learning patterns depending on nodule location, indicating the importance of nodule position in influencing ENB operative time and overall success.
[Clinical Characteristics and Prognosis of Myelodysplastic Syndromes Patients with Gene Mutation].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2024
Department of Hematology, The Second Affiliated Hospital (Tangdu Hospital) of Air Force Medical University, Xi'an 710038, Shaanxi Province, China.
Objective: To investigate the clinical characteristics and survival analysis of myelodysplastic syndromes (MDS) with gene mutation.
Methods: Clinical data of 177 newly diagnosed MDS patients admitted to the Department of Hematology, the Second Affiliated Hospital of Air Force Military Medical University from October 1, 2015 to October 31, 2022 were retrospectively analyzed. Gene mutation detection was performed by second-generation sequencing technology, and clinical characteristics and prognosis of patients with gene mutation were analyzed.
[Clinical application of a novel separated magnetic controlled forceps assisted single-incision laparoscopic cholecystectomy].
Zhonghua Wai Ke Za Zhi
May 2024
Department of General Surgery, the Second Affiliated Hospital (Tangdu Hospital) of Air Force Medical University,Xi'an 710038,China.
To explore the application value of a novel separated magnetic-controlled forceps in transumbilical single-incision laparoscopic cholecystectomy (SILC). This is a prospective case series study. Data from patients who underwent SILC at the Department of General Surgery, the Second Affiliated Hospital of Air Force Medical University from March to August 2023 were prospectively collected, based on inclusion and exclusion criteria.
View Article and Find Full Text PDFImpact of a novel prognostic model on allogeneic hematopoietic stem cell transplantation outcomes in patients with CMML.
Am J Hematol
September 2023
Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China.
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell malignancy, and allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only curable treatment. The outcomes after transplant are influenced by both disease characteristics and patient comorbidities. To develop a novel prognostic model to predict the post-transplant survival of CMML patients, we identified risk factors by applying univariable and multivariable Cox proportional hazards regression to a derivation cohort.
View Article and Find Full Text PDF[Clinical Characteristics and Prognosis of Acute Myeloid Leukemia Patients with ASXL1 Gene Mutation].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2021
Department of Hematology, The Second Affiliated Hospital (Tangdu Hospital) of Air Force Medical University, Xi'an 710038, Shaanxi province, China,E-mail:
Article Synopsis
- The study focused on the clinical characteristics and outcomes of acute myeloid leukemia (AML) patients with ASXL1 mutations, analyzing data from 229 newly diagnosed patients.
- Out of the patients studied, 19.6% had ASXL1 mutations, with frameshift mutations being the most frequent, and patients typically being older men with a history of myelodysplastic syndrome (MDS) or myeloproliferative neoplasms (MPN) and low initial white blood cell counts.
- Patients with ASXL1 mutations had a lower complete response (CR) rate compared to those without, and while there was a significant difference in survival rates up to 20 months, this difference was not observed beyond