9 results match your criteria: "the Ninth Medical Center of PLA General Hospital[Affiliation]"
Functionalized Iron Oxide Nanoparticles for Both Dual-Modal Imaging and Erythropoiesis.
ACS Appl Mater Interfaces
December 2024
Guangdong Provincial Key Laboratory of Advanced Biomaterials, Shenzhen Key Laboratory of Smart Healthcare Engineering, Department of Biomedical Engineering, Southern University of Science and Technology, No. 1088 Xueyuan Road, Nanshan District, Shenzhen, Guangdong 518055, P. R. China.
Cancer-related anemia (CRA), a complication of cancer, is considered the primary cause of high mortality for cancer patients. Safe and effective theranostics are desirable for realizing the high diagnostic accuracy of tumors and ameliorating CRA in the clinic. However, the available theranostics do not support dual-modal imaging and the amelioration of CRA at the same time.
View Article and Find Full Text PDFCorrection: The influencing factors for tracheostomy decannulation after traumatic cervical spinal cord injury: a retrospective study.
Spinal Cord
December 2024
School of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Simulated Microgravity can Promote the Apoptosis and Change Inflammatory State of Kupffer Cells.
Biomed Environ Sci
October 2024
Department of General Surgery, the 306th Hospital of PLA-Peking University Teaching Hospital, Beijing 100101, China;Department of General Surgery, the Ninth Medical Center of PLA General Hospital, Beijing 100101, China.
Objective: In this study, we analyzed the transcriptome sequences of Kupffer cells exposed to simulated microgravity for 3 d and conducted biological experiments to determine how microgravity initiates apoptosis in Kupffer cells.
Methods: Rotary cell culture system was used to construct a simulated microgravity model. GO and KEGG analyses were conducted using the DAVID database.
The influencing factors for tracheostomy decannulation after traumatic cervical spinal cord injury: a retrospective study.
Spinal Cord
November 2024
School of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Study Design: Retrospective study.
Objective: To investigate the outcomes and influencing factors of tracheostomy decannulation (TD) in persons with traumatic cervical spinal cord injury (SCI).
Setting: China Rehabilitation Research Center (CRRC) in Beijing, China.
Insights on neuropharmacological benefits and risks: Aconitum carmichaelii Debx.
Biomed Pharmacother
December 2024
State Key Laboratory of Advanced Medical Materials and Devices, Medical School, Tianjin University, 92 Weijin Road, Nankai District, Tianjin 300072, China. Electronic address:
Aconitum carmichaelii Debx., a traditional herb known for its potent bioactivities, has been widely used in Traditional Chinese Medicine, particularly in the forms of Chuanwu and Fuzi. Despite the therapeutic benefits of this plant, concerns have been raised regarding its neuropharmacological actions and potential neurotoxicity.
View Article and Find Full Text PDFNew insights into the intestinal barrier through "gut-organ" axes and a glimpse of the microgravity's effects on intestinal barrier.
Front Physiol
October 2024
Department of General Surgery, The Ninth Medical Center of PLA General Hospital, Beijing, China.
Gut serves as the largest interface between humans and the environment, playing a crucial role in nutrient absorption and protection against harmful substances. The intestinal barrier acts as the initial defense mechanism against non-specific infections, with its integrity directly impacting the homeostasis and health of the human body. The primary factor attributed to the impairment of the intestinal barrier in previous studies has always centered on the gastrointestinal tract itself.
View Article and Find Full Text PDFMARK2 variants cause autism spectrum disorder via the downregulation of WNT/β-catenin signaling pathway.
Am J Hum Genet
November 2024
Department of Medical Genetics, Capital Institute of Pediatrics, Beijing, China; Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. Electronic address:
Article Synopsis
- - Microtubule affinity-regulating kinase 2 (MARK2) is crucial for neurons to develop properly, and variants in MARK2 have been linked to autism spectrum disorder (ASD) and other neurodevelopmental issues, with most being loss-of-function mutations.
- - A study analyzed 31 individuals with MARK2 variants showing ASD along with unique facial features, finding that the loss of MARK2 disrupts early neuron development and leads to abnormal growth patterns in neural cells.
- - Research using iPSC models and MARK2-deficient mice highlighted the link between MARK2 loss and issues in neuronal function, connecting it to the reduction of the WNT/β-catenin signaling pathway, while suggesting lithium as a potential treatment
A retrospective analysis of simultaneous bilateral uniportal thoracoscopic surgeries for multiple primary bilateral pulmonary nodules.
J Cardiothorac Surg
October 2024
Department of Thoracic Surgery, The Ninth Medical Center of PLA General Hospital, No. 9 Anxiang North Lane, Deshengmenwai, Chaoyang District, Beijing, 100101, China.
Article Synopsis
- This study looked at a special type of surgery for people who have multiple small lumps in both lungs called nodules.
- 65 patients had a specific surgery called "uniportal video-assisted thoracoscopic surgery" that uses tiny cuts and cameras, and all surgeries went well without any needing bigger cuts.
- Most patients had a fast recovery with a few minor complications, and the results show that this surgery could be a good option for treating these lung nodules.
Environment-compatible heavy metal risk prediction method created with multilevel ensemble learning.
J Hazard Mater
December 2024
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, PR China. Electronic address:
Article Synopsis
- This study introduces a new health risk prediction method called MEL-HR, which uses multilevel ensemble learning to improve the accuracy of predicting health risks from heavy metal exposure.
- The experiments analyzed data from 490 samples, with strong predictive values (R values) for both point and interval predictions, indicating effective forecasting of health risks.
- Key environmental factors like longitude and soil organic matter were identified as significant alongside heavy metal factors, and the new method enhanced prediction accuracy by up to 40.36% compared to previous models.