7 results match your criteria: "the Netherlands. Electronic address: r.a.de.kleine@fsw.leidenuniv.nl.[Affiliation]"
Distress variability during exposure therapy and its relationship with PTSD symptom decline.
J Behav Ther Exp Psychiatry
December 2024
Leiden University, Department of Clinical Psychology, Institute of Psychology, Wassenaarseweg 52, 2333 AK, Leiden, the Netherlands; Parnassia Groep, PsyQ, Lijnbaan 4, 2512 VA, The Hague, the Netherlands. Electronic address:
Background And Objectives: Inhibitory Learning Theory (ILT) framework implies that in-session distress variability may promote extinction learning and thereby enhance exposure therapy efficacy. Thus far, research has mainly focused on in-session distress reduction. The aim of the current study was to assess whether in-session distress variability predicts next session PTSD symptom decline in PTSD patients receiving prolonged exposure (PE).
View Article and Find Full Text PDFAdvancements in Cognitive Behavioral Therapy.
Psychiatr Clin North Am
June 2024
LOEWE Spitzenprofessur für, Translationale Klinische Psychologie, Philipps-Universität Marburg, Marburg, Germany. Electronic address:
Impaired action-safety learning and excessive relief during avoidance in patients with anxiety disorders.
J Anxiety Disord
May 2023
Laboratory of Biological Psychology, KU Leuven, Belgium; Leuven Brain Institute, KU Leuven, Belgium.
Anxiety-related disorders are characterized by high levels of avoidance, but experimental research into avoidance learning in patients is scarce. To fill this gap, we compared healthy controls (HC, n = 47) with patients with obsessive-compulsive disorder (OCD, n = 33), panic disorder with agoraphobia (PDA, n = 40), and post-traumatic stress disorder (PTSD, n = 66) in a computer-based avoidance learning task, in order to examine (1) differences in rates of avoidance responses, (2) differences in action-safety learning during avoidance, and (3) differences in subjective relief following successful avoidance. The task comprised aversive negative pictures (unconditional stimulus, US) that followed pictures of two colored lamps (conditional stimuli, CS+), but not a third colored lamp (safety stimulus, CS-), and could be avoided by pressing a button during one CS+ (CS+ avoidable) but not the other (CS+ unavoidable).
View Article and Find Full Text PDFChanges in trauma-related cognitions predict subsequent symptom improvement during prolonged exposure in patients with childhood abuse-related PTSD.
Behav Res Ther
April 2023
Leiden University, Department of Clinical Psychology, Wassenaarseweg 52, 2333 AK, Leiden, the Netherlands; Parnassia Groep, PsyQ, Lijnbaan 4, 2512 VA, The Hague, the Netherlands. Electronic address:
Article Synopsis
- The study investigates how changes in negative posttraumatic cognitions may help reduce PTSD symptoms in patients undergoing Prolonged Exposure (PE) therapy, particularly those with a history of childhood abuse.
- By analyzing data from 83 patients at different treatment stages, the research shows that improvements in posttraumatic cognitions predict subsequent decreases in PTSD symptoms, rather than the other way around.
- The findings support the idea that addressing negative cognitions is crucial in PE therapy and suggest using the abbreviated Posttraumatic Cognitions Inventory (PTCI-9) to monitor these cognitive changes over time.
Does complex PTSD predict or moderate treatment outcomes of three variants of exposure therapy?
J Anxiety Disord
May 2021
PSYTREC, Bilthoven, the Netherlands; Radboud University, Behavioural Science Institute, Nijmegen, the Netherlands. Electronic address:
Article Synopsis
- - The study examined how Complex Posttraumatic Stress Disorder (CPTSD) affects treatment outcomes for various therapies aimed at addressing PTSD, specifically targeting childhood abuse-related cases.
- - Over half of the 149 patients studied were found to have CPTSD, which correlated with more severe symptoms and additional mental health issues at the start, but it did not predict or influence the effectiveness of treatment methods.
- - The research highlights that while CPTSD is associated with greater symptom severity and comorbidity, it does not determine how well a patient responds to different PTSD treatments, suggesting that more research with diverse samples is necessary.
Tonic immobility during re-experiencing the traumatic event in posttraumatic stress disorder.
Psychiatry Res
December 2018
Overwaal Centre of Expertise for Anxiety Disorders, OCD and PTSD, Institution for Integrated Mental Health Care Pro Persona, Nijmegen, The Netherlands; Radboud University, Behavioural Science Institute, NijCare, Nijmegen the Netherlands; PSYTREC, Bilthoven, The Netherlands.
Tonic Immobility (TI) is an evolved defence response, characterized by physical immobility. Peritraumatic TI has been linked to posttraumatic stress disorder (PTSD). However, samples sizes in clinical studies have been small, and little is known about TI reactions post trauma, for instance during trauma reminders.
View Article and Find Full Text PDFHarm expectancy violation during exposure therapy for posttraumatic stress disorder.
J Anxiety Disord
June 2017
Center for Anxiety Disorders Overwaal, Institution for Integrated Mental Health Care Pro Persona, Nijmegen, The Netherlands; Radboud University, Behavioural Science Institute, NijCare, Nijmegen, The Netherlands.
Exposure therapy has proven efficacy in the treatment of posttraumatic stress disorder (PTSD). Emotional processing theory proposes that fear habituation is a central mechanism in symptom reduction, but the empirical evidence supporting this is mixed. Recently it has been proposed that violation of harm expectancies is a crucial mechanism of action in exposure therapy.
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