Towards Automated Evaluation of Patient Centered Care-Assessing the Potential of Electronic Health Records.

Providing patient centered care is a crucial element of high quality care. It can be defined as a responsive way of caring for and empowering patients, embodying compassion, empathy, and responsiveness to the patient's needs. The aim of this study was to assess the potential of using EHRs as information source in the development of tools for assessing PCC.

Effects of gender and psychiatric comorbidity on the age of illness onset and the outcome of psychotic depression-A birth cohort study.

Background: Psychotic depression (PD) is an under-researched disorder with severe symptoms and course of illness. Little is known about gender differences relating to this condition and possible variation of prognosis based on comorbid pathology. Our aim was to analyze the effects of gender and psychiatric comorbidities on the age of illness onset and on the outcome of psychotic depression.

Clinical experience and cost evaluation of magnetic resonance imaging -only workflow in radiation therapy planning of prostate cancer.

Background And Purpose: In radiation therapy (RT), significant improvements have been made recently particularly in the practices of planning imaging. This study aimed to conduct a cost evaluation between magnetic resonance imaging (MRI) -only and combined computed tomography (CT) and MRI workflows.

Materials And Methods: The time-driven activity-based costing (TDABC) model was used to conduct a cost evaluation between the two workflows in those steps, where cost differences were expected.

Complications and reoperations related to tension band wiring and plate osteosynthesis of olecranon fractures.

Background: Olecranon fractures are common and usually treated operatively either by tension band wiring (TBW) or plate fixation (PF). The aim of this study was to assess early complications and reoperations and their predictive factors related to those operative methods.

Methods: A retrospective analysis of all patients with an operatively treated olecranon fracture between 2007 and 2017 at Turku University hospital was performed.

Early childhood and adolescent risk factors for psychotic depression in a general population birth cohort sample.

Background And Purpose: In the group of severe mental disorders, psychotic depression (PD) is essentially under-researched. Knowledge about the risk factors is scarce and this applies especially to early risk factors. Our aim was to study early childhood and adolescent risk factors of PD in a representative birth cohort sample with a follow-up of up to 50 years.

Child involvement in oral health education interventions - a systematic review of randomised controlled studies.

Objectives: This systematic review examines elementary school-aged children's involvement in oral health interventions.

Methods: A systematic review of randomised controlled studies was carried out according to the PRISMA guidelines. PubMed, CINAHL, Embase, and Scopus databases were searched for publications listed between 2008-2018.

Pain process of patients with cardiac surgery-Semantic annotation of electronic patient record data.

Aims And Objectives: To describe and compare the pain process of the patients' with cardiac surgery through nurses' and physicians' documentations in the electronic patient records.

Background: Postoperative pain assessment and management should be documented regularly, to ensure optimal pain care process for patients. Despite availability of evidence-based guidelines, pain assessment and documentation remain inadequate.

Clinical characteristics and outcomes of psychotic depression in the Northern Finland Birth Cohort 1966.

Background: Psychotic depression (PD) is heavily understudied despite high mortality and the severe course of illness. A majority of the studies conducted so far are also largely based on selected clinical samples. The aim of this study was to examine the clinical characteristics of PD in a representative prospective birth cohort sample.

Using Positron Emission Tomography in Revealing the Mystery of General Anesthesia: Study Design Challenges and Opportunities.

Functional neuroimaging with positron emission tomography (PET) is one of the cornerstones for studying the central nervous system effects of general anesthetics and anesthesia mechanisms. General anesthesia offers a unique and safe way to directly manipulate consciousness, and can thus be used as a powerful research tool to study the neurobiology of human consciousness. In this chapter, we will address the possibilities of PET imaging in revealing the mysteries of general anesthesia and anesthetic induced unconsciousness and summarize some of the recent advancements in the field.

Differentiating Drug-related and State-related Effects of Dexmedetomidine and Propofol on the Electroencephalogram.

Background: Differentiating drug-related changes and state-related changes on the electroencephalogram during anesthetic-induced unconsciousness has remained a challenge. To distinguish these, we designed a rigorous experimental protocol with two drugs known to have distinct molecular mechanisms of action. We hypothesized that drug- and state-related changes can be separated.

Low free 25-hydroxyvitamin D and high vitamin D binding protein and parathyroid hormone in obese Caucasians. A complex association with bone?

Background: Studies have shown altered vitamin D metabolism in obesity. We assessed differences between obese and normal-weight subjects in total, free, and bioavailable 25-hydroxyvitamin D (25(OH)D, 25(OH)DFree, and 25(OH)DBio, respectively), vitamin D binding protein (DBP), parathyroid hormone (PTH) and bone traits.

Methods: 595 37-47-year-old healthy Finnish men and women stratified by BMI were examined in this cross-sectional study.

Statistical parsing of varieties of clinical Finnish.

Objectives: In this paper, we study the development and domain-adaptation of statistical syntactic parsers for three different clinical domains in Finnish.

Methods And Materials: The materials include text from daily nursing notes written by nurses in an intensive care unit, physicians' notes from cardiology patients' health records, and daily nursing notes from cardiology patients' health records. The parsing is performed with the statistical parser of Bohnet (http://code.

Nursing student control over using a computer simulation program about empowering discourse.

Nurses find empowering discourse as a patient education intervention demanding, so using methods that support the constructive learning of empowering discourse during their education would be helpful. The aim of this descriptive, comparative study was to evaluate student control when using a computer simulation program that facilitates learning about empowering discourse. The study hypothesis was as follows: Students can control the use of an empowering discourse computer simulation program regardless of their sociodemographic background and study orientation.

Stability of chemical and immunochemical analytes in uncentrifuged plasma samples.

Background: The stability of analyte concentrations in plasma after prolonged contact with blood cells in uncentrifuged lithium-heparin gel tubes was studied.

Methods: To investigate the stability of concentrations of 26 chemistry and 15 immunochemistry analytes, the simultaneously drawn samples (n = 50) were measured after 6 h storage at +8 degrees C and +22 degrees C in whole blood and after immediate separation of plasma. The analyte concentrations were measured with a Roche Modular PPEE analyser using reagents from Roche Diagnostics.

Automated measurement of 25-OH vitamin D3 on the Roche Modular E170 analyzer.

Background: The first commercial direct automated immunoassay specific for 25-OH vitamin D(3) (25-OH-D(3)) was recently introduced for use on Roche Diagnostics immunoassay analyzers. We assessed the analytical performance of the Elecsys 25-OH-D(3) assay on a Roche Modular E 170 analyzer.

Methods: The Elecsys 25-OH-D(3) assay is a direct electrochemiluminescence immunoassay for human serum or plasma.