2 results match your criteria: "the Fourth People's Hospital of Haikou City[Affiliation]"

Role of type VI secretion system protein TssJ-3 in virulence and intracellular survival of Burkholderia pseudomallei.

Biochem Biophys Res Commun

November 2023

Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Tropical Disease Control, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199, China. Electronic address:

Article Synopsis
  • * Research on B. pseudomallei strains with and without the tssJ-3 gene revealed that the lack of this gene significantly inhibited bacterial growth, biofilm formation, motility, and ability to invade host cells.
  • * The study found that tssJ-3 plays a crucial regulatory role in gene expression related to biofilm and flagellum development, suggesting that targeting this gene could lead to new treatments for infections caused by B. pseudomallei. *
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Periodontitis is a prevalent chronic inflammatory disease. Circular RNAs (circRNAs) have been revealed to play roles in the inflammatory response. Hence, this work aimed to explore the role and mechanism of circ_0062491 in periodontitis progression.

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