[Effect of mitochondrial apoptosis on pulmonary fibrosis in rats with severe scald injury].

Objective: To explore the role of mitochondrial apoptosis on pulmonary fibrosis in rats with severe scald injury.

Methods: According to the random digital table, a total number of 32 Wistar rats were divided into 4 groups: sham burn (group A), burn group (group B), 12-week post burn recovery group (group C), and 12-week post burn recovery plus a second burn injury group (group D). In group A and group B, lung tissues were harvested on post burn day 4.

[Comparative proteomics study on lung tissue in early stage of burn-blast combined injury in rats].

Objective: To explore changes in the proteomics of lung tissue in early stage of burn-blast combined injury in rats.

Methods: According to a random digital table, a total number of 18 Sprague Dawley (SD) rats were divided into burn-blast combined injury group (n=9) and blast injury group (n=9). Lung protein samples were collected at 6 h post injury.

Efficacy of perioperative dexmedetomidine in postoperative neurocognitive function: a meta-analysis.

Neuroprotective effects of dexmedetomidine are reported in preclinical and clinical studies but evidence regarding the postoperative neurocognitive function is not as clear. This study performed a meta-analysis on outcomes of studies which examined neurocognitive performance by using valid assessment tools before and after perioperative dexmedetomidine treatment. Literature was searched in several electronic databases and studies were selected by following précised inclusion criteria.

Levo-tetrahydropalmatine attenuates oxaliplatin-induced mechanical hyperalgesia in mice.

Common chemotherapeutic agents such as oxaliplatin often cause neuropathic pain during cancer treatment in patients. Such neuropathic pain is difficult to treat and responds poorly to common analgesics, which represents a challenging clinical issue. Corydalis yanhusuo is an old traditional Chinese medicine with demonstrated analgesic efficacy in humans.