48 results match your criteria: "the First Affiliated Hospital of Tsinghua University[Affiliation]"
EClinicalMedicine
January 2025
College of Competitive Sports, Beijing Sport University, Beijing, China.
Background: Given the distinctive physiological characteristics of pregnant women, non-pharmacological therapies are increasingly being used to improve depressive and anxiety symptoms. Our objective was to explore and compare the impact of various non-pharmacological interventions in improving depressive and anxiety symptoms, and to identify the most effective strategies for pregnant women with depressive and/or anxiety symptoms.
Methods: We conducted a systematic search of PubMed, Embase, the Cochrane Library, and Web of Science for randomized controlled trials (RCTs) that compared non-pharmacological interventions to usual care, from the inception of each database up to October 5, 2024.
Eur J Intern Med
December 2024
Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, PR China. Electronic address:
Objectives: The purpose of this study was to determine whether our new thinking guidance named OPACCUS (oxygen metabolism, perfusion, arterial tension, cardiac output, systemic congestion, unregulated host response and search for inciting illness event) with 7 questions you need to ask before shock therapy and evidences provided by critical ultrasound considering hemodynamics, the unregulated host response and inciting illness event would improve mortality in shock patients.
Design: A multicenter, prospective, observational cohort study.
Setting: Intensive care units of 20 hospitals in Southwest China.
Hepatol Commun
January 2025
Liver Research Center, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health and National Clinical Research Center of Digestive Diseases, Beijing, China.
J Crit Care
February 2025
Department of Critical Care Medicine, the Fourth Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address:
Objective: This study explores alterations in renal cortical perfusion post-Early Goal-Directed Therapy (EGDT) in sepsis patients, to investigate its association with major adverse kidney events within 30 days (MAKE-30) and identify hemodynamic factors associated with renal cortical perfusion.
Methods: Sepsis patients admitted to the ICU from Jan 2022 to Jul 2023 were prospectively enrolled. Contrast-enhanced ultrasound (CEUS) assessed renal cortical perfusion post-EGDT.
Lab Med
November 2024
Department of Blood Transfusion, The First Affiliated Hospital of Tsinghua University, Beijing, China.
Zhonghua Nan Ke Xue
June 2024
Department of Urology, The First Affiliated Hospital of Tsinghua University, Beijing 100016, China.
Objective: To compare thulium laser enucleation of the prostate (ThuLEP) with plasma kinetic resection of the prostate (PKRP) in the treatment of BPH.
Methods: We retrospectively analyzed the medical records of 160 cases of BPH treated by ThuLEP (the observation group, n = 80) or PKRP (the control group, n = 80) in our hospital from January 2021 to December 2023. We recorded the operation time, bladder irrigation time, catheter retention time, hospitalization time, postoperative complications, and pre- and postoperative maximum urinary flow rate (Qmax), residual urine volume (PVR), prostate-specific antigen (PSA) and prostate volume, followed by comparison of the data obtained between the two groups of patients.
Ann Vasc Surg
January 2025
Department of Vascular Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. Electronic address:
J Anesth
October 2024
Department of Intensive Care Unit (ICU), The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050011, People's Republic of China.
Oliguria is a clinical symptom characterized by decreased urine output, which can occur at any stage of acute kidney injury and also during renal replacement therapy. In some cases, oliguria may resolve with adjustment of blood purification dose or fluid management, while in others, it may suggest a need for further evaluation and intervention. It is important to determine the underlying cause of oliguria during renal replacement therapy and to develop an appropriate treatment plan.
View Article and Find Full Text PDFZhonghua Nei Ke Za Zhi
May 2024
Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730,China.
The evolution of critical care medicine is inextricably linked to the development of critical care procedures. These procedures not only facilitate diagnosis and treatment of critically ill patients, but also provide valuable insights into disease pathophysiology. While critical care interventions offer undeniable benefits, the potential for iatrogenic complications necessitates careful consideration.
View Article and Find Full Text PDFZhonghua Nei Ke Za Zhi
May 2024
Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100041, China.
Mult Scler Relat Disord
June 2024
Department of Neurology, China-Japan Friendship Hospital, Beijing, 100029 China. Electronic address:
Background: Rituximab (RTX), an anti-CD20 monoclonal antibody, has shown promise in managing neuromyelitis optica spectrum disorders (NMOSD) by depleting B cells and reducing relapses. However, there is no consensus on the optimal RTX dosing regimen, and genetic factors, such as FCGR3A-V158F polymorphism, may influence treatment outcomes. This study investigates how FCGR3A-V158F genotypes influence RTX efficacy in Chinese NMOSD patients under varying dosing regimens and aims to optimize treatment protocols.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
September 2024
Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Purpose: This large retrospective, single-center, follow-up study investigated the endoscopic prelacrimal recess approach (PLRA) for treating maxillary sinus inverted papilloma (MSIP).
Methods: Between January 2007 and November 2022, patients with MSIP treated with PLRA were enrolled. Data on clinical manifestations, imaging, and surgical procedures were collected.
Front Robot AI
November 2023
Institute for Precision Medicine, Tsinghua University, Beijing, China.
Gait is an important basic function of human beings and an integral part of life. Many mental and physical abnormalities can cause noticeable differences in a person's gait. Abnormal gait can lead to serious consequences such as falls, limited mobility and reduced life satisfaction.
View Article and Find Full Text PDFZhonghua Nei Ke Za Zhi
December 2023
Department of Critical Care Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100041, China.
Acute respiratory and circulatory disorders are the most common critical syndromes, the essence of which is damage to the organs/systems of the heart and lungs. These comprise the essential manifestation of disease and injury progression to the severe stage. Its development involves the following components: individual specificity, primary disease strike, dysregulation of the host's response, and systemic disorders.
View Article and Find Full Text PDFRen Fail
November 2023
Department of Critical Care Medicine, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
The multiple etiological characteristics of acute kidney injury (AKI) have brought great challenges to its clinical diagnosis and treatment. Renal injury in critically ill patients always indicates hemodynamic injury. The Critical Care UltraSound Guided (CCUSG)-ABCDE protocol developed by the Chinese Critical Ultrasound Study Group (CCUSG), respectively, includes A diagnosis and risk assessment and uses B-mode ultrasound, Color doppler ultrasound, spectral Doppler ultrasound, and contrast Enhanced ultrasound to obtain the hemodynamic characteristics of the kidney so that the pathophysiological mechanism of the occurrence and progression of AKI can be captured and the prognosis of AKI can be predicted combined with other clinical information; therefore, the corresponding intervention and treatment strategies can be formulated to achieve targeted, protocolized, and individualized therapy.
View Article and Find Full Text PDFBMC Oral Health
October 2023
Department of Stomatology, Beijing Friendship Hospital, Capital Medical University, 95 Yong 'an Road, Xicheng District, Beijing, 100050, China.
Objective: Accurate quantification of the root surface area (RSA) plays a decisive role in the advancement of periodontal, orthodontic, and restorative treatment modalities. In this study, we aimed to develop a dynamic threshold-based computer-aided system for segmentation and calculation of the RSA of isolated teeth on cone-beam computed tomography (CBCT) and to assess the accuracy of the measured data.
Method: We selected 24 teeth to be extracted, including single-rooted and multi-rooted teeth, from 22 patients who required tooth extraction.
Digit Health
August 2023
Department of Pulmonary Vessel and Thrombotic Disease, Sixth Medical Centre, Chinese PLA General Hospital, Beijing, China.
Objective: To validate a single-lead electrocardiogram algorithm for identifying atrial fibrillation, atrial premature beats, ventricular premature beats, and sinus rhythm.
Methods: A total of 656 subjects aged 19 to 94 years were enrolled. Participants were simultaneously tested with a wristwatch (Huawei Watch GT2 Pro, Huawei Technologies Co.
Front Comput Neurosci
August 2023
The First Affiliated Hospital of Tsinghua University, Beijing, China.
Objective: This study aimed to investigate the relationship between hearing impairment, depressive symptoms, and social participation in older adults.
Methods: The study used data from the China Health and Retirement Longitudinal Study (CHARLS) in 2013 and 2018, which included 3,980 samples. The analysis was conducted using cross-lagged structural equation modeling with SPSS 23.
Curr Comput Aided Drug Des
May 2024
Department of Pain Medicine, The First Affiliated Hospital of Tsinghua University, Beijing 100016, China.
Objective: This study aimed to analyze the potential targets and mechanism of the Tiannanxing-shengjiang drug pair in pain treatment using network pharmacology and molecular docking technology.
Methods: The active components and target proteins of Tiannanxing-Shengjiang were obtained from the TCMSP database. The pain-related genes were acquired from the DisGeNET database.
Zhonghua Nei Ke Za Zhi
May 2023
Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
We wished to establish an expert consensus on late stage of critical care (CC) management. The panel comprised 13 experts in CC medicine. Each statement was assessed based on the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) principle.
View Article and Find Full Text PDFFront Pediatr
April 2023
Department of Pediatrics, Heart Center, The First Affiliated Hospital of Tsinghua University, Beijing, China.
Objective: Radiofrequency catheter ablation (RFCA) has evolved into an effective and safe technique for the treatment of tachyarrhythmia in children. Concerns about children and involved medical staff being exposed to radiation during the procedure should not be ignored. "Fluoroscopy integrated 3D mapping", a new 3D non-fluoroscopic navigation system software (CARTO Univu Module) could reduce fluoroscopy during the procedure.
View Article and Find Full Text PDFCurr Med Imaging
June 2023
Department of Cardiology, Beijing Huaxin Hospital, the First Affiliated Hospital of Tsinghua University, Beijing, China.
Background: Traditional radiography angles do not adequately reveal the shape and position of the right ventricular pacing electrode.
Objective: This study aimed to explore better radiography angles with the help of cardiac computed tomography (CT).
Methods: We analyzed the cardiac CT images of consecutive outpatients from 2018 to 2019.
J Clin Transl Hepatol
February 2023
Department of Gastroenterology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Background And Aims: Collagen β(1-O) galactosyltransferase 25 domain 1 (GLT25D1) is associated with collagen production and glycosylation, and its knockout in mice results in embryonic death. However, its role in liver fibrosis remains elusive, particularly in hepatic stellate cells (HSCs), the primary collagen-producing cells associated with liver fibrogenesis. Herein, we aimed to elucidate the role of GLT25D1 in HSCs.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
October 2022
Department of Pediatrics, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.
Background: Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by attention deficit, hyperactivity, and impulsivity. Jing-Ning Granules (JNG) is a traditional Chinese medicine (TCM) that can alleviate ADHD. Although JNG is commonly used for the effective treatment of ADHD and has obtained the national invention patent, the exact mechanism of action remains unclear.
View Article and Find Full Text PDFWorld J Clin Cases
October 2022
Gastroenterology Department, The First Affiliated Hospital of Tsinghua University, Beijing 100016, China.
Background: Solitary splenic tuberculosis (TB) is unusual and rarely reported. Whether splenic TB is best treated surgically is still controversial. We describe a 73-year-old man with solitary splenic TB and no extrapulmonary TB.
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