32 results match your criteria: "the First Affiliated Hospital Zhengzhou University[Affiliation]"
Background: Obesity induced by antipsychotics severely increases the risk of many diseases and significantly reduces quality of life. Genome Wide Association Studies has identified fat-mass and obesity-associated (FTO) gene associated with obesity. The relationship between the FTO gene and drug-induced obesity is unclear.
View Article and Find Full Text PDFSerum levels of BDNF, folate and homocysteine: in relation to hippocampal volume and psychopathology in drug naïve, first episode schizophrenia.
Schizophr Res
October 2014
Henan Province Biological Psychiatry Key Laboratory, Xinxiang Medical University, Xinxiang, China; Henan Province Mental Hospital, The Second Affiliated Hospital/Xinxiang Medical University, Xinxiang, China. Electronic address:
Objective: The present study was to examine serum levels of brain-derived neurotrophic factor (BDNF), folate, homocysteine (Hcy), and their relationships with hippocampal volume and psychopathology in drug naïve, first episode schizophrenia.
Method: Drug naïve, first episode schizophrenia patients and healthy controls were enrolled in the study. Serum levels of BDNF, folate and Hcy were measured using enzyme-linked immunosorbent assay (ELISA), electrochemiluminescence immunoassay (ECLIA), and enzymatic cycling method respectively.
Prolactin serum levels correlate with inflammatory status in drug-naïve first-episode schizophrenia.
World J Biol Psychiatry
September 2014
The First Affiliated Hospital/Zhengzhou University, Zhengzhou , China.
Objectives: The present study was to examine the relationship between serum levels of prolactin and the inflammatory status in drug-naïve, first-episode schizophrenia patients with normal weight.
Methods: Patients with normal weight, drug-naïve, first-episode schizophrenia and healthy controls were enrolled in the study. Serum levels of prolactin (PRL) were measured using electrical chemiluminescence immunoassay.
Activation of Th17 cells in drug naïve, first episode schizophrenia.
Prog Neuropsychopharmacol Biol Psychiatry
June 2014
Henan Province Biological Psychiatry Key Laboratory, Xinxiang Medical University, Xinxiang, China; Henan Province Mental Hospital, The Second Affiliated Hospital/Xinxiang Medical University, Xinxiang, China. Electronic address:
Objective: The present study was to examine the role of pro-inflammatory T helper 17 (Th17) cells in drug naïve, first episode schizophrenia.
Method: Patients with normal weight, drug naïve, first episode schizophrenia and healthy controls were enrolled in the study. Flow cytometric analysis was performed to analyze the proportion of Th17 cells among the CD4(+) T cells.
Changes in pro-inflammatory cytokines and body weight during 6-month risperidone treatment in drug naïve, first-episode schizophrenia.
Psychopharmacology (Berl)
January 2014
The First Affiliated Hospital/Zhengzhou University, Zhengzhou, China, 450052,
Objective: The present study aimed to examine the changes in pro-inflammatory cytokines and body weight during 6-month risperidone treatment in drug naïve, first-episode schizophrenia.
Methods: Sixty-two drug naïve, first-episode schizophrenia (SZ group) and 60 healthy individuals (control group) were enrolled in the study. Serum interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) levels, and body weight were measured at baseline for both groups, and repeated for the SZ group at five different time points during 6-month risperidone treatment.
[Clinical research on surgical treatment for non-small cell lung cancer of diameter less than 2 cm].
Zhonghua Yi Xue Za Zhi
August 2013
Department of Thoracic Surgery, the First Affiliated Hospital Zhengzhou University, Zhengzhou 450052, China.
Objective: To discuss the model of reasonable dissection extent of mediastinal lymph nodes in non-small cell lung cancer of diameter less than 2 cm.
Method: A study was carried on the clinical data of 192 patients with NSCLC of diameter less than 2 cm undergoing curative resection and mediastinal lymph nodes dissection,According to the size of tumor and the pathology quick report.
Results: The survival rates of patient was statistically significant difference (P < 0.
Elevated levels of adiponectin and other cytokines in drug naïve, first episode schizophrenia patients with normal weight.
Schizophr Res
October 2013
The First Affiliated Hospital/Zhengzhou University, Zhengzhou, China; Henan Province Biological Psychiatry Key Laboratory, Xinxiang Medical University, Xinxiang, China; Psychotic Disorders Program, UMass Memorial Medical Center/University of Massachusetts Medical School, Worcester, MA, United States.
Objective: The study was to examine the levels of adiponectin (APN) and other cytokines, and body metabolism in drug naïve, first episode schizophrenia patients with normal weight.
Methods: Ninety-six drug naïve, first episode schizophrenia patients with normal weight (SZ group), 60 healthy individuals with normal weight (control group), and 60 overweight or obese but otherwise healthy individuals (obesity group) were enrolled in the study. Serum levels of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and APN were measured using enzyme linked immunosorbent assay (ELISA).