Hippocampal subfields in adolescent anorexia nervosa.

Patients with anorexia nervosa (AN) exhibit volume reduction in cerebral gray matter (GM), and several studies report reduced hippocampus volume. The hippocampal subfields (HS) are functionally and structurally distinct, and appear to respond differently to neuropathology. The aim of this study was to investigate HS volumes in adolescent females with restrictive AN compared to a healthy age-matched control group (HC).

The practice of support personnel, supervised by physiotherapists, in Norwegian reablement services.

Objectives: Reablement is a relatively new service targeting people with or at risk of functional decline. The approach is team based, and physiotherapists (PTs), occupational therapists, and nurses have the responsibility to guide and supervise the support personnel, referred to as home trainers (HTs). The aim of this study was to explore how the HTs follow up instructions and supervision by PTs in reablement.

Is a modified Global Trigger Tool method using automatic trigger identification valid when measuring adverse events?

Objectives: To evaluate a modified Global Trigger Tool (GTT) method with manual review of automatic triggered records to measure adverse events.

Design: A cross-sectional study was performed using the original GTT method as gold standard compared to a modified GTT method.

Setting: Medium size hospital trust in Northern Norway.

An improved method for counting stressful life events (SLEs) when predicting mental health and wellness.

Objective: Checklists for registering stressful life events (SLEs) generally correlate negatively, but weakly, with mental health outcome measures. Thus, the present study examined various methodological approaches for improving these relationships.

Design: A total of 1679 participants (women = 943, men = 736, M age-39.

Flagella-mediated secretion of a novel cytotoxin affecting both vertebrate and invertebrate hosts.

Using as an infection host model for predator interactions, we discovered a bacterial cytotoxin, MakA, whose function as a virulence factor relies on secretion via the flagellum channel in a proton motive force-dependent manner. The MakA protein is expressed from the polycistronic (otility-ssociated lling factor) operon. Bacteria expressing induced dramatic changes in intestinal morphology leading to a defecation defect, starvation and death in .

Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma.

Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive tumors. The aim of this study was to detect differentially expressed genes and metabolites according to reactive stroma content measured on the exact same prostate cancer tissue sample. Reactive stroma was evaluated using histopathology from 108 fresh frozen prostate cancer samples gathered from 43 patients after prostatectomy (Biobank1).

Direct Measurement of the Magnitude of the van der Waals Interaction of Single and Multilayer Graphene.

Vertical stacking of monolayers via van der Waals (vdW) assembly is an emerging field that opens promising routes toward engineering physical properties of two-dimensional materials. Industrial exploitation of these engineering heterostructures as robust functional materials still requires bounding their measured properties so as to enhance theoretical tractability and assist in experimental designs. Specifically, the short-range attractive vdW forces are responsible for the adhesion of chemically inert components and are recognized to play a dominant role in the functionality of these structures.

Pooled Analysis of Nine Cohorts Reveals Breast Cancer Risk Factors by Tumor Molecular Subtype.

Various subtypes of breast cancer defined by estrogen receptor (ER), progesterone receptor (PR), and HER2 exhibit etiologic differences in reproductive factors, but associations with other risk factors are inconsistent. To clarify etiologic heterogeneity, we pooled data from nine cohort studies. Multivariable, joint Cox proportional hazards regression models were used to estimate HRs and 95% confidence intervals (CI) for molecular subtypes.

A group-based, individualized physiotherapy intervention for people with multiple sclerosis-A qualitative study.

Background And Purpose: Group-based interventions for people with multiple sclerosis (MS) have gained increased attention in the field of physiotherapy research. However, no studies have investigated whether or how the prevailing principle of individualization is embedded in such interventions. The purpose of this study was to investigate how professional actions and interactions affect individualized exercise adaptations in a group intervention for people with MS.

Can the health related quality of life measure QOLIBRI- overall scale (OS) be of use after stroke? A validation study.

Background: Brief measures of health-related quality of life (HRQOL) that assess both patient-reported functioning and well-being after stroke are scarce. The objective of this study was to examine reliability and validity of one of these measures, the patient-reported Quality of Life after Brain Injury-Overall Scale (QOLIBRI-OS), in patients after stroke.

Methods: Stroke survivors were examined prospectively using survey methods.

Single-Input and Multiple-Output Surface Acoustic Wave Sensing for Damage Quantification in Piezoelectric Sensors.

The main aim of the paper is damage detection at the microscale in the anisotropic piezoelectric sensors using surface acoustic waves (SAWs). A novel technique based on the single input and multiple output of Rayleigh waves is proposed to detect the microscale cracks/flaws in the sensor. A convex-shaped interdigital transducer is fabricated for excitation of divergent SAWs in the sensor.

Do Norwegian Sami and non-indigenous individuals understand questions about mental health similarly? A SAMINOR 2 study.

The Western culturally developed Hopkins Symptom Checklist (HSCL-10) is a self-report measure of mental distress widely used for both clinical and epidemiological purposes - also in the multiethnic epidemiological SAMINOR studies in Northern Norway, but without any proper cross-cultural validation. Our objective was to test invariance of the HSCL-10 measurements among Sami and the non-indigenous majority population in Northern Norway (participants in the SAMINOR 2 study) and whether the previously used HSCL-10 cut-off level (1.85) fits the Sami subgroups in the study.

Correction to: Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.

The co-author name Immaculata DeVivo was incorrectly published. The correct name is given below.

Factors Determining the Success and Failure of eHealth Interventions: Systematic Review of the Literature.

Background: eHealth has an enormous potential to improve healthcare cost, effectiveness, and quality of care. However, there seems to be a gap between the foreseen benefits of research and clinical reality.

Objective: Our objective was to systematically review the factors influencing the outcome of eHealth interventions in terms of success and failure.

Epigenome-wide association study of adiposity and future risk of obesity-related diseases.

Background: Obesity is an established risk factor for several common chronic diseases such as breast and colorectal cancer, metabolic and cardiovascular diseases; however, the biological basis for these relationships is not fully understood. To explore the association of obesity with these conditions, we investigated peripheral blood leucocyte (PBL) DNA methylation markers for adiposity and their contribution to risk of incident breast and colorectal cancer and myocardial infarction.

Methods: DNA methylation profiles (Illumina Infinium HumanMethylation450 BeadChip) from 1941 individuals from four population-based European cohorts were analysed in relation to body mass index, waist circumference, waist-hip and waist-height ratio within a meta-analytical framework.

Parental and child factors associated with participation in a randomised control trial of an Internet-assisted parent training programme.

Background: Parental training is an effective way to treat and prevent children's conduct problems, but knowledge of who participates in such initiatives is limited.

Method: This study examined child and family factors associated with participation in an Internet-assisted parent training programme. The parents of 4-year-old children with high levels of disruptive behaviour in a region of Finland were offered the opportunity to participate in a randomised controlled trial of the Strongest Families Smart Website intervention (SFSW).

Hardy-type inequalities in fractional -discrete calculus.

The first power weighted version of Hardy's inequality can be rewritten as [Formula: see text] where the constant [Formula: see text] is sharp. This inequality holds in the reversed direction when [Formula: see text]. In this paper we prove and discuss some discrete analogues of Hardy-type inequalities in fractional -discrete calculus.

Studies on the effects of LPS, ß-glucan and metabolic inhibitors on the respiratory burst and gene expression in Atlantic salmon macrophages.

Reactive oxygen species (ROS) production in macrophage-like cells is induced as an antimicrobial defence against invading pathogens. In this study, we have explored how different stimuli and metabolic inhibitors affect the level of respiratory burst in Atlantic salmon (Salmo salar L.) head kidney macrophage-like cells.

How physiotherapists supervise to enhance practical skills in dedicated aides of toddlers with cerebral palsy: A qualitative observational study.

Background: Physiotherapy from an early age is considered important for children with cerebral palsy (CP). In preschool, dedicated aides are responsible for the daily follow-up and training under the supervision of a physiotherapist (PT). Knowledge is sparse regarding what is created and achieved in clinical practice involving triads (i.

Contribution of Patient-reported Symptoms Before Palliative Radiotherapy to Development of Multivariable Prognostic Models.

Background/aim: Typically, prognostic scores predicting survival in patients with metastatic cancer are based on disease- and patient-related factors, such as extent of metastases, age and performance status. Patient-reported symptoms have been included less often. Our group has assessed all patients with the Edmonton Symptom Assessment System (ESAS, a one-sheet questionnaire addressing 11 major symptoms and wellbeing on a numeric scale of 0-10) before palliative radiotherapy (PRT) since 2012.

Does parental mental health moderate the effect of a telephone and internet-assisted remote parent training for disruptive 4-year-old children?

This study explores the moderators affecting the success of an Internet-based and telephone assisted remote parent training intervention and compares them to an educational control group. We prospectively identified 464 parents who reported at a health check that their 4-year-old children showed elevated levels of externalizing behavior. The moderators explored included parental attention deficit and hyperactivity disorder (ADHD) and parental distress.

How Should Palliative Thoracic Radiotherapy Be Fractionated for Octogenarians with Lung Cancer?

Background/aim: Geriatric oncology practice should be based on dedicated studies and real-world experience. Therefore, we evaluated survival outcomes after palliative thoracic radiotherapy in octogenarian patients with lung cancer and analyzed prognostic factors.

Patients And Methods: We carried out a retrospective analysis of 51 patients with a median age of 83 years.