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Early coagulation disorder and the predictive value of D-dimer for deep vein thrombosis in major burn patients.

Burns

January 2025

Institute of Burn Research, Southwest Hospital, the Army Medical University (the Third Military Medical University), Chongqing 400038, China; State Key Laboratory of Trauma, Burn and Combined Injury, China. Electronic address:

Objective: To investigate coagulation disorders and thrombotic complications in the early stage after burn, and to evaluate the predictive reliability of D-dimer for deep vein thrombosis (DVT) diagnosis in major burn patients.

Methods: This retrospective study was performed in the Department of Burns, Southwest Hospital, and included 288 adult major burn patients (≥40 % TBSA) without prophylactic anticoagulant therapy. All patients received routine screening assays of coagulation indicators and Doppler ultrasound scan (DUS) during the 28 days post-burn regardless of the clinical symptoms of DVT.

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