7 results match your criteria: "the Armed Police Corps Hospital of Anhui[Affiliation]"
Gallbladder cancer: surgical treatment, immunotherapy, and targeted therapy.
Postgrad Med
April 2024
Department of General Surgery, The Armed Police Corps Hospital of Anhui, Hefei, China.
Article Synopsis
- * Many patients, however, are diagnosed too late for surgery and must rely on non-surgical treatments, such as chemotherapy, radiotherapy, and emerging therapies like immunotherapy and targeted therapy.
- * This review highlights newer surgical methods and the latest advancements in immunotherapy and targeted therapy related to gallbladder cancer research.
LncRNA PCAT6 is a predictor of poor prognosis of colorectal cancer.
J Gastrointest Oncol
February 2024
Department of General Surgery, The Armed Police Corps Hospital of Anhui, Hefei, China.
Background: The long non-coding RNA (lncRNA) prostate cancer-associated transcript 6 (PCAT6) has been studied in many cancers, yet its relationship with colorectal cancer (CRC) remains poorly defined. Here, we conducted an analysis of The Cancer Genome Atlas (TCGA) database to better clarify the role of PCAT6 in this cancer type.
Methods: Wilcoxon rank-sum tests were utilized to assess relative levels of PCAT6 in CRC tumors and normal tissues, while logistic regression analyses were utilized to compare the relationships between PCAT6 levels and clinicopathological findings.
Comprehensive analysis of EML2 as a prognostic biomarker in colon cancer.
Int J Clin Exp Pathol
January 2024
Department of General Surgery, The Armed Police Corps Hospital of Anhui Hefei, Anhui, China.
Article Synopsis
- EML2 is a gene linked to multiple cancers, including colon cancer, and its expression levels may serve as a prognostic indicator for disease outcomes.
- The study analyzed EML2 expression via TCGA and GEO databases, finding it significantly overexpressed in colon cancer compared to normal tissue, with potential as a diagnostic biomarker (AUC = 0.738).
- Higher EML2 levels were connected to worse overall survival and influenced immune cell infiltration, particularly affecting GTPase binding and specific immune cell types.
INPP4B exerts a dual role in gastric cancer progression and prognosis.
J Cancer
October 2021
Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, People's Republic of China.
Inositol polyphosphate 4-phosphatase type II (INPP4B) negatively regulates PI3K-Akt signalling and plays diverse roles in different types of cancer, but its role in gastric cancer (GC) is still unknown. Our study aimed to investigate the function and clinical relevance of INPP4B in GC. INPP4B expression was detected in GC tissues and nontumour tissues.
View Article and Find Full Text PDFMiR-3614-5p Is a Potential Novel Biomarker for Colorectal Cancer.
Front Genet
May 2021
Department of General Surgery, The Armed Police Corps Hospital of Anhui, Hefei, China.
MiR-3614-5p has been found in a variety of cancers including colorectal cancer. However, the association of miR-3614-5p with colorectal cancer is still unclear. Based on the Cancer Genome Atlas (TCGA) database, the relationship between miR-3614-5p and colorectal cancer can be proved.
View Article and Find Full Text PDFExpression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cells.
BMC Cancer
April 2021
Department of General Surgery, the Armed Police Corps Hospital of Anhui, Hefei, 230041, People's Republic of China.
Background: Inositol polyphosphate 4-phosphatase type II (INPP4B) is a negative regulator of the PI3K-Akt signalling pathway and plays a contradictory role in different types of cancers. However, the its biological role played by INPP4B in human gallbladder cancer (GBC) has not been elucidated. In this study, we investigated the expression, clinical significance and biological function of INPP4B in GBC patients and cell lines.
View Article and Find Full Text PDFIncreased expression of RBMS3 predicts a favorable prognosis in human gallbladder carcinoma.
Oncol Rep
July 2020
Department of General Surgery, The Armed Police Corps Hospital of Anhui, Hefei, Anhui 230041, P.R. China.
Multiple regions in the short arm of chromosome 3 are frequently deleted in a variety of solid tumors including gallbladder carcinoma (GBC). RNA binding motif, single‑stranded interacting protein 3 (RBMS3), a tumor suppressor gene (TSG), is located in this region. However, the role of RBMS3 in GBC remains unclear.
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