5 results match your criteria: "the Affiliated Fourth Hospital of China Medical University[Affiliation]"
The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study.
BMC Cancer
June 2023
Department of Oncology and Central Laboratory, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, China.
Background: Pepsinogen C (PGC) is expressed in chief cells, fundic mucous neck cells, and pyloric gland cells of gastric epithelium and also in breast, prostate, lung, and seminal vesicles.
Methods: We explored the clinicopathological and prognostic significances of PGC mRNA using pathological and bioinformatics analyses. We generated PGC knockout and PGC-cre transgenic mice to observe the effects of PGC deletion and PTEN abrogation in PGC-positive cells on gastric carcinogenesis.
Background: The outcome of deploying balloon-mounted stents for symptomatic intracranial atherosclerotic stenosis (ICAS) has not been fully investigated. In this study we evaluate the safety and long-term outcome of using balloon-mounted stents to treat symptomatic ICAS in comparison with the WEAVE/WOVEN study.
Methods: In a multicenter registry study of stenting for symptomatic intracranial artery stenosis in China, 159 patients treated with an intracranial balloon-mounted stent approved by the China Food and Drug Administration were evaluated.
Protein arginine methyltransferase 5 promotes bladder cancer growth through inhibiting NF-kB dependent apoptosis.
EXCLI J
November 2018
Department of Urology, the Affiliated Fourth Hospital of China Medical University, Shenyang, Liaoning, China.
Protein arginine methyltransferase 5 (PRMT5) has emerged as a key regulator of tumorigenesis. However, how PRMT5 functions in bladder cancer, the most common malignancy of the urological system, is unknown. We described here that PRMT5 is highly expressed in bladder cancer cell lines and primary human bladder cancer tissues.
View Article and Find Full Text PDFStenting for symptomatic intracranial arterial stenosis in China: 1-year outcome of a multicentre registry study.
Stroke Vasc Neurol
September 2018
Department of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.
Background And Purpose: A multicentre prospective registry study of individually tailored stenting for a patient with symptomatic intracranial atherosclerotic stenosis (ICAS) combined with poor collaterals in China showed that the short-term safety and efficacy of stenting was acceptable. However, it remained uncertain whether the low event rate could be of a long term. We reported the 1-year outcome of this registry study to evaluate the long-term efficacy of individually tailored stenting for patients with severe symptomatic ICAS combined with poor collaterals.
View Article and Find Full Text PDFThirty-Day Outcome of a Multicenter Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China.
Stroke
October 2015
From the Departments of Interventional Neuroradiology (Z.M.) and Neurology (Yilong Wang, Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China; Department of Neurology, The Affiliated Hospital of Qingdao University Medical College, Qingdao, China (Y.Z.); Department of Neurology, Xin Qiao Hospital, Third Military Medical University, Chongqing, China (J.S.); Department of Neurology, Baotou Central Hospital, Baotou, China (C.J.); Department of Neurology, Linyi People's Hospital, Linyi, China (Q.Z.); Department of Neurology, Xi Nan Hospital, Third Military Medical University, Chongqing, China (K.C.); Department of Neurology, The Hospital of Chifeng City, Chifeng, China (L.L.); Department of Neurosurgery, The PLA General Hospital, Beijing, China (B.L.); Department of Neurology, The Lanzhou General Hospital of PLA, Lanzhou, China (X.S.); Department of Neurology, The Affiliated Fourth Hospital of China Medical University, Shenyang, China (L.G.); Department of Neurology, Zhujiang Hospital, Southern Medical University, Guangzhou, China (Yajie Liu); Department of Interventional Therapy, The First Affiliated Hospital of Dalian Medical University, Dalian, China (F.W.); Department of Neurosurgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, China (Yongli Li); Department of Interventional Radiology, Cangzhou Central Hospital, Cangzhou, China (T.L.); and Department of Neurology, West China Hospital, Sichuan University, Chengdu, China (H.Z.).
Background And Purpose: Although recent trials have suggested that stenting is worse than medical therapy for patients with severe symptomatic intracranial atherosclerotic stenosis, it is not clear whether this conclusion applies to a subset of patients with hypoperfusion symptoms. To justify for a new trial in China, we performed a multicenter prospective registry study to evaluate the safety and efficacy of endovascular stenting within 30 days for patients with severe symptomatic intracranial atherosclerotic stenosis.
Methods: Patients with symptomatic intracranial atherosclerotic stenosis caused by 70% to 99% stenosis combined with poor collaterals were enrolled.