Irregular Bone Defect Repair Using Tissue-Engineered Periosteum in a Rabbit Model.

Background: In previous studies, we succeeded in repairing a long bone defect with tissue-engineered periosteum (TEP), fabricated by incorporating rabbit mesenchymal stem cells with small intestinal submucosa. In this study, we investigated the feasibility of allogeneic irregular bone defect repair using TEP.

Methods: We performed a subtotal resection of the scapula in 36 rabbits to establish a large irregular bone defect model.

2018 Chinese Pediatric Cardiology Society (CPCS) guideline for diagnosis and treatment of syncope in children and adolescents.

Syncope belongs to the transient loss of consciousness (TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death.

Multiple myeloma with pathologically proven skull plasmacytoma after a mild head injury: Case report.

Rationale: MM is a malignant tumor originating from the plasma cells of the bone marrow. Central nervous system myelomatosis is very rare and may be a complication of MM.

Patient Concerns: A 60-year-old man presented with a slowly growing soft mass at his right frontal scalp after a mild head injury 6 months ago.

Could yoga practice improve treatment-related side effects and quality of life for women with breast cancer? A systematic review and meta-analysis.

Aim: To determine if yoga as a complementary and alternative therapy was associated with enhanced health and treatment-related side effects in patients with breast cancer. This systematic review examines whether yoga practice provides any measurable benefit, both physically and psychologically, for women with breast cancer.

Methods: PubMed, EMBASE and the Cochrane Library for randomized controlled trials (RCTs) throughout June 2013.

Effect of tissue factor knockdown on the growth, invasion, chemoresistance and apoptosis of human gastric cancer cells.

This study aimed to explore the role of tissue factor (TF) and evaluate its antitumor effects in the biological processes of gastric cancer cells using the application of RNA interference technology to silence TF in the SGC7901 gastric cancer cell line. Specific small interfering RNA (siRNA) designed for targeting human TF was transfected into SGC7901 cells. The expression levels of TF in the cells were detected by reverse transcription-polymerase chain reaction.

Comparative study between tissue-engineered periosteum and structural allograft in rabbit critical-sized radial defect model.

The purpose of this study was to compare the efficacy of tissue-engineered periosteum (TEP) to allgeneic bone in repairing segmental bone defect. TEP was fabricated with osteoinduced rabbit bone marrow mesenchymal stem cells (MSCs) and porcine small intestinal submucosa (SIS). Allogrfats were cryopreserved radial segments of New Zealand Rabbits.

Evaluation of immunocompatibility of tissue-engineered periosteum.

Tissue-engineered periosteum (TEP) and 'intramembranous ossification' may be an alternative approach to bone tissue engineering. In the previous study we attained successful bone defect reparation with homemade TEP in an allogenic rabbit model. But its allogenic immunocompatibility remained unknown.

Synergistic effects of galectin-1 and reactive astrocytes on functional recovery after contusive spinal cord injury.

Introduction: Galectin-1 (Gal-1), a carbohydrate-binding protein, is differentially expressed by various normal and pathological tissues and appears to be functionally polyvalent. Recent evidence indicates that Gal-1 is involved in the proliferation of adult neural progenitor cells in neurogenic regions during adulthood. However, localization and functional roles of Gal-1 in the adult spinal cord have not been clarified.

Anatomical transverse patella double tunnel reconstruction of medial patellofemoral ligament with a hamstring tendon autograft for recurrent patellar dislocation.

Introduction: The purpose of this study was to describe our transverse patella double tunnel technique to reconstruct the medial patellofemoral ligament (MPFL) with a hamstring tendon autograft in patients who suffered recurrent dislocation of the patella, and to evaluate the intermediate-term outcomes of reconstruction treatment.

Materials And Methods: Fifty-nine consecutive knees (52 patients) with recurrent dislocation of the patella without marked predisposing anatomic abnormalities and radiographically documented moderate/severe osteochondral lesions were included in the study. Outcomes were assessed with physical and radiographic examination, the Kujala and the modified Cincinnati scores preoperatively and postoperatively at 3, 6, 12, 36, 60 and 84 months.

The study of the feasibility of segmental bone defect repair with tissue- engineered bone membrane: a qualitative observation.

The objective of the study was to investigate the feasibility of intramembranous osteogenesis from tissue-engineered bone membrane in vivo. Bone marrow mesenchymal stem cells (MSCs) of rabbits were harvested, expanded and some of them were induced into osteoblasts. Porcine small intestinal submucosa (SIS) was converted by a series of physical and chemical procedures into a scaffold.