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Acromegaly and coronary disease: an integrated evaluation of conventional coronary risk factors and coronary calcifications detected by computed tomography.
J Clin Endocrinol Metab
October 2006
Sezione di Endocrinologia, Pad. H, piano 4 Azienda Ospedaliera Universitaria Policlinico G. Martino, Via Consolare Valeria 1, 98125 Messina, Italy.
Context: Coronary atherosclerosis in acromegaly was not extensively investigated in the literature until now. At autopsy, it was demonstrated in about 20% of patients with long-lasting disease, and myocardial infarction was reported as cause of death in a quarter of acromegalics.
Objective: The objective of the study was to evaluate coronary atherosclerosis in a cohort of acromegalics with controlled or uncontrolled disease.