Optimizing soil health through activated acacia biochar under varying irrigation regimes and cultivars for sustainable wheat cultivation.

Wheat, a staple food crop globally, faces the challenges of limited water resources and sustainable soil management practices. The pivotal elements of the current study include the integration of activated acacia biochar (AAB) in wheat cultivation under varying irrigation regimes (IR). A field trial was conducted in the Botanical Garden, University of the Punjab, Lahore during 2023-2024, designed as a split-split-plot arrangement with RCBD comprising three AAB levels (0T, 5T, and 10T, T = tons per hectare) three wheat cultivars (Dilkash-2020, Akbar-2019, and FSD-08) receiving five IR levels (100%, 80%, 70%, 60%, and 50% field capacity).

Cost Consciousness Among Dermatologists.

Background: Physicians are responsible for most decisions related to resource allocation and healthcare expenditures, and should consider cost in their decision-making approach.

Objective: To measure cost consciousness among dermatologists, evaluate their understanding of cost-related concepts, and explore what prevents them from factoring cost into their daily practice decisions.

Methods: This cross-sectional survey-based study involved dermatologists from different practice types and work environments.

Effects of the Stanford Chronic Conditions Model on Behavioral and Clinical Indicators in Saudi Arabia: A Prospective Quasi-Experimental Study.

Purpose: This study aimed to evaluate the 6-month impact of the Chronic Disease Self-Management Program based on the Stanford chronic condition model on behavioral and clinical indicators in individuals with chronic illnesses.

Patients And Methods: This prospective, quasi-experimental study was conducted in primary healthcare centers located in Riyadh, Saudi Arabia. A total of 110 adults aged 18 years or older, living with at least one chronic disease, and receiving treatment at a primary healthcare center were included.

Constructing a knee osteoarthritis transplant via the neutrality aggregation operators under spherical fuzzy Z-numbers framework.

Understanding the biomechanics of osteoarthritis is necessary for designing a biomedical knee implant to reduce pain, increase mobility, and enhance the patient's quality of life. The most appropriate implant design may be chosen by using Multi-Attribute Group Decision-Making (MAGDM) techniques, which include a number of variables including material characteristics, biomechanical performance, cost-effectiveness, and patient-specific requirements. Compared to conventional fuzzy set structures, Spherical Fuzzy -Number Sets ( S) provide an enhanced method for resolving uncertainty in MAGDM and are more suited for handling complicated decision-making situations.

Nanotechnological Advances in Burn Wound Care: Silver Sulfadiazine-Loaded Nanosuspension-Based Chitosan-Incorporated Nanogel for Partial Thickness Burns.

Burn lesions damage the skin's outermost defensive layer, allowing pathogenic microbes including to infiltrate. Silver sulfadiazine (SSD) is an effective antibacterial agent approved by U.S.

Food Safety Concerns in Pakistan: Monitoring of Antimicrobial-Resistant Bacteria and Residue Contamination in Commercially Available Fish and Poultry Meat Samples.

Food safety is a critical issue in the 21st century due to antibiotic-resistant bacteria causing harmful foodborne diseases. This comprehensive study meticulously examined the presence of bacterial isolates, quinolone residue, and antimicrobial resistance genes in samples of broiler and fish meat. Forty samples were collected from various locations in the Faisalabad metropolis.

Management of radiotherapy-induced hyposalivation using photobiomodulation therapy: a case series.

It is not uncommon for individuals receiving radiotherapy for head and cancers to experience dry mouth sensation (xerostomia), salivary hypofunction (hyposalivation) and taste changes. The present study aimed to evaluate the short-term effectiveness of biweekly photobiomodulation therapy (PBMT) in managing these radiotherapy-induced adverse effects and its impact on oral health-related quality of life. Ten patients who developed xerostomia and hyposalivation secondary to radiotherapy for head and neck cancer were included.

Exploring the utility of different bulking agents for speeding up the composting process of household kitchen waste.

Household kitchen waste (HKW) is produced in large quantity and its management is difficult due to high moisture content and complex organic matter. Aerobic composting of HKW is an easy, efficient, cost-effective and eco-friendly method. This study is designed to achieve a zero-waste concept and to convert HKW.

Examining the landscape transformation and temperature dynamics in Pakistan.

This study aims to examine the landscape transformation and temperature dynamics using multiple spectral indices. The processes of temporal fluctuations in the land surface temperature is strongly related to the morphological features of the area in which the temperature is determined, and the given factors significantly affect the thermal properties of the surface. This research is being conducted in Pakistan to identify the vegetation cover, water bodies, impervious surfaces, and land surface temperature using decadal remote sensing data with four intervals during 1993-2023 in the Mardan division, Khyber Pakhtunkhwa.

Designing of an innovative conserved multiepitope subunit vaccine targeting SARS-CoV-2 glycoprotein and nucleoprotein through immunoinformatic.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has imposed substantial challenges on our society due to the COVID-19 pandemic. This virus relies heavily on its surface glycoprotein (S-glycoprotein) to facilitate attachment, fusion, and entry into host cells. While the nucleoprotein (N) in the ribonucleoprotein core binds to the viral RNA genome.

Comparative assessment of empirical and hybrid machine learning models for estimating daily reference evapotranspiration in sub-humid and semi-arid climates.

Improving the accuracy of reference evapotranspiration (RET) estimation is essential for effective water resource management, irrigation planning, and climate change assessments in agricultural systems. The FAO-56 Penman-Monteith (PM-FAO56) model, a widely endorsed approach for RET estimation, often encounters limitations due to the lack of complete meteorological data. This study evaluates the performance of eight empirical models and four machine learning (ML) models, along with their hybrid counterparts, in estimating daily RET within the Gharb and Loukkos irrigated perimeters in Morocco.

Hypomagnesemia in adults with type 2 diabetes mellitus in Riyadh, Saudi Arabia: A cross-sectional study.

This study investigates the prevalence of hypomagnesemia in adults with type 2 diabetes mellitus (T2DM) in Riyadh, Saudi Arabia, and examines its association with various metabolic parameters. Conducted as a cross-sectional study at King Saud University, Riyadh, it included 294 Saudi adults aged 25 to 65 years, comprising 119 T2DM patients, 80 prediabetics, and 95 nondiabetic controls. Participants underwent physical examinations, and fasting blood samples were analyzed for glucose, glycated hemoglobin (HbA1c), lipid profile, and serum magnesium levels.

Analysis of Synonymous Codon Usage bias of Lassa virus.

Lassa virus genome consists of two single-stranded, negative-sense RNA segments that lie in the genus Arenavirus. The disease associated with the Lassa virus is distributed all over the world, with approximately 3,000,000-5,000,000 infections diagnosed annually in West Africa. It shows high health risks to the human being.

The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry.

Objectives: To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.

Methods: A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry.

Factors Influencing Nursing Interns' Engagement in Fall Prevention Activities in Saudi Arabia.

Aim: To assess the knowledge, attitudes and engagement of nursing interns regarding fall prevention activities during their internship within hospital settings.

Design: This study used a cross-sectional design.

Methods: This was a cross-sectional, descriptive, correlational study.

Exploring the Anti-Adherence Potential of Skt35 to Combat Catheter-Associated Staphylococcus aureus Infections: Efficacy, Toxicity and Mechanism of Action.

Catheter-associated urinary tract infections (CAUTIs), often caused by biofilm-forming Staphylococcus aureus, present significant clinical challenges. Skt35, a dioxopiperidinamide derivative of cinnamic acid, was investigated for its potential antibacterial and antibiofilm activities against S. aureus biofilms.

Antiangiogenic potential of extracts and molecular docking study by targeting VEGFR-2 pathway.

Background: Anti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. Natural sources like plants are currently being explored for its antiangiogenic activity as they are factories of various phytochemicals. The goal of the current study is to investigate the antiangiogenic potential of () by using chorioallantoic membrane (CAM) assay and molecular docking.

OpenAI's Sora and Google's Veo 2 in Action: A Narrative Review of Artificial Intelligence-driven Video Generation Models Transforming Healthcare.

The rapid evolution of generative artificial intelligence (AI) has introduced transformative technologies across various domains, with text-to-video (T2V) generation models emerging as transformative innovations in the field. This narrative review explores the potential of T2V AI generation models used in healthcare, focusing on their applications, challenges, and future directions. Advanced T2V platforms, such as Sora Turbo (OpenAI, Inc.

Green synthesis of Ag-Fe bimetallic nanoparticles using fungal filtrates: unlocking multifunctional medical and environmental applications.

The current investigation focuses on synthesizing Ag-Fe bimetallic nanoparticles (AgFe-BMNPs) using cell-free filtrates of the as a novel fungal reducing agent. The optical, morphological, and surface properties of these fungus-fabricated AgFe-BMNPs and their monometallic counterparts (AgNPs and FeNPs) were analyzed using sophisticated nanotechnology instruments. The UV-visible spectrum showed peaks at 231 nm and 415 nm for BMNPs and 450 nm and 386 nm for AgNPs and FeNPs, respectively.

A concept analysis of vicarious resilience in mental health nursing.

Objective: The introduction of the vicarious resilience concept in psychology and mental health nursing literature is a highly promising advancement. By utilizing this novel concept, experts in various domains can enhance their comprehension of how to foster resilience in individuals by observing and learning from the resilience of others. This concept analysis aims to elucidate the concept of vicarious resilience in mental health nursing by defining its related attributes, antecedents, and consequences.

Novel Frostbite Cooling Device for Real-time Assessment and Prevention of Chemotherapy-induced Peripheral Neuropathy.

Background: Chemotherapy-induced peripheral neuropathy (CIPN) affects 29%-68% of patients undergoing anticancer treatments within the first month. Traditional cryotherapy methods, such as frozen gloves, can pose risks. This study evaluates the cool-water electric circulation seat (CECS), which maintains a constant 15°C, as a safer alternative.

Thalamic volume differentiates multiple sclerosis from neuromyelitis optica spectrum disorder: MRI-based retrospective study.

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are distinct demyelinating diseases of the central nervous system, each characterized by unique patterns of motor, sensory, and visual dysfunction. While MS typically affects the brain and spinal cord, NMOSD predominantly targets the optic nerves and spinal cord. This study aims to elucidate the morphometric differences between MS and NMOSD by focusing on gray matter volume changes in specific brain regions.

Beyond Chemistry: Investigating the Physical, Pharmacological, and Computational Aspects of Polyoxometalate Integrated Solid Lipid Nanoparticles for Cancer Treatment.

Purpose: The solid lipid nanoparticles of transitional metal complexes (POMs) were prepared with natural lipids with the aim of developing a safer therapeutic approach for cancer treatment.

Methods: Natural lipids were used to create solid lipid nanoparticles containing transitional metal complexes (POMs).

Results: The nanoparticles had displayed appreciable entrapment and loading percentage of PW.

Reasons and Features of Patients Who Leave the Emergency Department Without Being Seen.

Emergency medicine practitioners encounter significant challenges related to patients who leave emergency departments (EDs) without being seen (LWBS) in the ED. We aimed to assess the characteristics, reasons, and rate of patients who left without being seen in the tertiary teaching hospital ED of King Khalid University Hospital in Riyadh, Saudi Arabia. A qualitative prospective observational study was conducted from January 4, 2023, to May 17, 2023, among patients who left the ED without being seen in the King Khalid University Hospital, King Saud University Medical City, a tertiary hospital in Riyadh, Saudi Arabia.

Green hydrothermal approach for the synthesis of carbon quantum dots from waste tea bags for acrylamide detection in drinking water: A fluorescence assay validated by HPLC-PDA analysis.

The study focused on converting tea bag waste into strong fluorescence carbon quantum dots (TBW-CQDs) for the detection of acrylamide in drinking water, antimicrobial activity, and photocatalytic degradation. The TBW-CQDs exhibited blue luminescence and maximum absorbance at 287 nm under UV light and distinctive fluorescence emission and excitation wavelengths at 425 nm and 287 nm, respectively. TBW-CQDs revealed a particle size of 8.