43,943 results match your criteria: "king Saud University[Affiliation]"

Background: Magnesium (Mg) is essential for plant growth and development and plays critical roles in physiological and biochemical processes. Mg deficiency adversely affects growth of plants by limiting shoot and root development, disturbing the structure and membranes of the grana, reducing photosynthesis efficiency, and lowering net CO assimilation. The MGT (Magnesium transporter) family is responsible for the absorption and transportation of magnesium in plants.

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This study investigates the synergistic effects of zinc oxide nanoparticles (ZnO NPs) and melatonin (MT) on Fragaria × ananassa (strawberry) plants under drought stress, focusing on growth, fruit biomass, and stress tolerance. ZnO NPs enhance nutrient uptake and stress resistance, while MT regulates growth hormones and boosts photosynthetic efficiency. Seven treatments were evaluated: T1 (no stress, 0.

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Identification of potent TMPRSS4 inhibitors through structural modeling and molecular dynamics simulations.

Sci Rep

January 2025

Laboratory of Molecular Chemistry, Department of Chemistry, Faculty of Sciences Semlalia, Cadi Ayyad University, BP 2390, 40000, Marrakech, Morocco.

TMPRSS4, a transmembrane serine protease type II, is associated with various pathological illnesses. It has been found to activate SARS-CoV-2, enhance viral infection of human small-intestinal enterocytes and is overexpressed in different types of cancers. Therefore, this study aims to disover potential TMPRSS4 inhibitors that have better binding affinity than the approved inhibitors: 2-hydroxydiarylamide and tyroserleutide.

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Growing emission of environmentally-hazardous greenhouse pollutants (especially CO) has motivated the researchers to apply gas-liquid membrane contactors as an easy-to-operate and cost-effective technique for increasing their separation efficiency from different sources. In the current decades, ionic liquids (ILs) have shown their potential in the gas separation industry owing to their noteworthy advantages such as great capacity, excellent adjustability and suitable thermal/chemical stability compared to commonly-employed amine absorbents. This investigation aims to analytically/numerically determine the separation yield of CO from CO₂/N gaseous flow using novel -Ethyl-3-methylimidazolium dicyanamide ([emim][CN]) IL inside the gas-liquid contactor.

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The Efficacy of 3 Bleaching Methods on Stained Polymer-Based CAD/CAM Materials.

Int Dent J

January 2025

Biomaterials Science, Division of Dentistry, School of Medical Sciences, University of Manchester, Manchester, UK.

Introduction And Aims: This study aimed to investigate the efficacy of 3 bleaching methods on stained polymer-based CAD/CAM blocks in terms of surface roughness, hardness stability, discolouration reduction and susceptibility to re-staining following bleaching.

Methods: Two-mm-thick slabs (N = 128) were prepared from CeraSmart (CS), Grandio Blocs (GB), Vita Enamic (VE), and direct resin composite GrandioSO (RC). Coffee-stained specimens (n = 8) were subdivided into bleaching (BL) groups: in-office bleaching (OB), home bleaching (HB), whitening mouthwash (MW), and a control group with 14-day storage in water (CL).

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Diabetes affects approximately 422 million people worldwide, leading to 1.5 million deaths annually and causing severe complications such as kidney failure, neuropathy, and cardiovascular disease. Aldose reductase (AR), a key enzyme in the polyol pathway, is an important therapeutic target for managing these complications.

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Osteoporosis in men-East and West: Can the twain meet? A perspective from Asia.

Osteoporos Sarcopenia

December 2024

Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Singapore.

Osteoporosis in men remains a significantly underrecognized condition, with notable differences in bone mineral density (BMD) and fracture risk between Asian and Western populations. Despite 30% of hip fractures globally occurring in men, they are less likely to be diagnosed or treated for osteoporosis, especially in resource-limited settings. Given these disparities, a deeper understanding of osteoporosis epidemiology and treatment efficacy in men is essential, particularly in Asian populations.

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Objective: The objective of this study is to determine the effectiveness and safety profile of coblation tongue base reduction (CBTR) compared to radiofrequency base of tongue (RFBOT) reduction on sleep-related outcomes in patients with obstructive sleep apnea (OSA).

Data Sources: PubMed, Scopus, Web of Science, and Cochrane Database of Systematic Reviews databases.

Review Methods: Literature search by 2 independent authors was conducted using the abovementioned databases.

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Introduction: A vital component of public health that needs a lot of attention is oral health care for people with special needs. The phrase "special needs" describes a wide range of issues pertaining to behavior, development, health, and emotions that require specific medical and educational support. These individuals often present with complex oral health care needs that require specialized knowledge and skills.

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Wheat, a staple food crop globally, faces the challenges of limited water resources and sustainable soil management practices. The pivotal elements of the current study include the integration of activated acacia biochar (AAB) in wheat cultivation under varying irrigation regimes (IR). A field trial was conducted in the Botanical Garden, University of the Punjab, Lahore during 2023-2024, designed as a split-split-plot arrangement with RCBD comprising three AAB levels (0T, 5T, and 10T, T = tons per hectare) three wheat cultivars (Dilkash-2020, Akbar-2019, and FSD-08) receiving five IR levels (100%, 80%, 70%, 60%, and 50% field capacity).

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Cost Consciousness Among Dermatologists.

Clin Cosmet Investig Dermatol

January 2025

Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Background: Physicians are responsible for most decisions related to resource allocation and healthcare expenditures, and should consider cost in their decision-making approach.

Objective: To measure cost consciousness among dermatologists, evaluate their understanding of cost-related concepts, and explore what prevents them from factoring cost into their daily practice decisions.

Methods: This cross-sectional survey-based study involved dermatologists from different practice types and work environments.

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Purpose: This study aimed to evaluate the 6-month impact of the Chronic Disease Self-Management Program based on the Stanford chronic condition model on behavioral and clinical indicators in individuals with chronic illnesses.

Patients And Methods: This prospective, quasi-experimental study was conducted in primary healthcare centers located in Riyadh, Saudi Arabia. A total of 110 adults aged 18 years or older, living with at least one chronic disease, and receiving treatment at a primary healthcare center were included.

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Understanding the biomechanics of osteoarthritis is necessary for designing a biomedical knee implant to reduce pain, increase mobility, and enhance the patient's quality of life. The most appropriate implant design may be chosen by using Multi-Attribute Group Decision-Making (MAGDM) techniques, which include a number of variables including material characteristics, biomechanical performance, cost-effectiveness, and patient-specific requirements. Compared to conventional fuzzy set structures, Spherical Fuzzy -Number Sets ( S) provide an enhanced method for resolving uncertainty in MAGDM and are more suited for handling complicated decision-making situations.

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Burn lesions damage the skin's outermost defensive layer, allowing pathogenic microbes including to infiltrate. Silver sulfadiazine (SSD) is an effective antibacterial agent approved by U.S.

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Food safety is a critical issue in the 21st century due to antibiotic-resistant bacteria causing harmful foodborne diseases. This comprehensive study meticulously examined the presence of bacterial isolates, quinolone residue, and antimicrobial resistance genes in samples of broiler and fish meat. Forty samples were collected from various locations in the Faisalabad metropolis.

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Management of radiotherapy-induced hyposalivation using photobiomodulation therapy: a case series.

Lasers Med Sci

January 2025

Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

It is not uncommon for individuals receiving radiotherapy for head and cancers to experience dry mouth sensation (xerostomia), salivary hypofunction (hyposalivation) and taste changes. The present study aimed to evaluate the short-term effectiveness of biweekly photobiomodulation therapy (PBMT) in managing these radiotherapy-induced adverse effects and its impact on oral health-related quality of life. Ten patients who developed xerostomia and hyposalivation secondary to radiotherapy for head and neck cancer were included.

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Household kitchen waste (HKW) is produced in large quantity and its management is difficult due to high moisture content and complex organic matter. Aerobic composting of HKW is an easy, efficient, cost-effective and eco-friendly method. This study is designed to achieve a zero-waste concept and to convert HKW.

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This study aims to examine the landscape transformation and temperature dynamics using multiple spectral indices. The processes of temporal fluctuations in the land surface temperature is strongly related to the morphological features of the area in which the temperature is determined, and the given factors significantly affect the thermal properties of the surface. This research is being conducted in Pakistan to identify the vegetation cover, water bodies, impervious surfaces, and land surface temperature using decadal remote sensing data with four intervals during 1993-2023 in the Mardan division, Khyber Pakhtunkhwa.

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has imposed substantial challenges on our society due to the COVID-19 pandemic. This virus relies heavily on its surface glycoprotein (S-glycoprotein) to facilitate attachment, fusion, and entry into host cells. While the nucleoprotein (N) in the ribonucleoprotein core binds to the viral RNA genome.

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Comparative assessment of empirical and hybrid machine learning models for estimating daily reference evapotranspiration in sub-humid and semi-arid climates.

Sci Rep

January 2025

Prince Sultan Bin Abdulaziz International Prize for Water Chair, Prince Sultan Institute for Environmental, Water and Desert Research, King Saud University, P.O. Box 2454, Riyadh 11451, Saudi Arabia.

Improving the accuracy of reference evapotranspiration (RET) estimation is essential for effective water resource management, irrigation planning, and climate change assessments in agricultural systems. The FAO-56 Penman-Monteith (PM-FAO56) model, a widely endorsed approach for RET estimation, often encounters limitations due to the lack of complete meteorological data. This study evaluates the performance of eight empirical models and four machine learning (ML) models, along with their hybrid counterparts, in estimating daily RET within the Gharb and Loukkos irrigated perimeters in Morocco.

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This study investigates the prevalence of hypomagnesemia in adults with type 2 diabetes mellitus (T2DM) in Riyadh, Saudi Arabia, and examines its association with various metabolic parameters. Conducted as a cross-sectional study at King Saud University, Riyadh, it included 294 Saudi adults aged 25 to 65 years, comprising 119 T2DM patients, 80 prediabetics, and 95 nondiabetic controls. Participants underwent physical examinations, and fasting blood samples were analyzed for glucose, glycated hemoglobin (HbA1c), lipid profile, and serum magnesium levels.

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Analysis of Synonymous Codon Usage bias of Lassa virus.

Virus Res

January 2025

Medical Big Data Center, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong Province 510080, China. Electronic address:

Lassa virus genome consists of two single-stranded, negative-sense RNA segments that lie in the genus Arenavirus. The disease associated with the Lassa virus is distributed all over the world, with approximately 3,000,000-5,000,000 infections diagnosed annually in West Africa. It shows high health risks to the human being.

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The clinical assessment of lung involvement in patients with Still's disease, results from the multicentre international AIDA Network Still's Disease Registry.

Rheumatology (Oxford)

January 2025

Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.

Objectives: To assess the lung involvement in patients with Still's disease, an inflammatory disease assessing both children and adults. To exploit possible associated factors for parenchymal lung involvement in these patients.

Methods: A multicentre observational study was arranged assessing consecutive patients with Still's disease characterized by the lung involvement among those included in the AIDA (AutoInflammatory Disease Alliance) Network Still's Disease Registry.

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