1 results match your criteria: "kafedra akusherstva i ginekologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta im. N.I. Pirogova[Affiliation]"
Klin Med (Mosk)
December 1997
Gematologicheskiĭ nauchnyĭ tsentr RAMN, Tsentr planirovaniia sem'i i reproduktsii, kafedra akusherstva i ginekologii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta im. N.I. Pirogova, Moskva.
RhD immunisation which follows pregnancy can be prevented by administration to the rhesus-negative mother of 20 micrograms anti-D immunoglobulin per 1 ml of D-positive fetal red cells in the maternal circulation. With the aim of substitution of polyclonal anti-D with monoclonal one we developed human-mouse cell lines producing anti-RhD IgG1 by fusing EBV-transformed human immune lymphocytes with murine myeloma. After several clonings and passages the EBV genome was eliminated from the cell lines.
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