Nanoparticle-based colorimetric assays for early and rapid screening of the oncogenic HPV variants 16 and 18.

Cervical cancer is predominantly caused by human papillomavirus (HPV), with oncogenic strains HPV 16 and 18 accounting for most cases worldwide. Prompt and precise identification of these high-risk HPV types is essential for enhancing patient outcomes as it enables timely intervention and management. However, the existing HPV detection techniques are time-consuming, expensive, and require highly skilled personnel.

Reaction-Free Energies for Complexation of Carbohydrates by Tweezer Diboronic Acids.

The accurate calculation of reaction-free energies (Δ°) for diboronic acids and carbohydrates is challenging due to reactant flexibility and strong solute-solvent interactions. In this study, these challenges are addressed with a semiautomatic workflow based on quantum chemistry methods to calculate conformational free energies, generate microsolvated solute structural ensembles, and compute Δ°. Workflow parameters were optimized for accuracy and precision while controlling computational costs.

Laser-induced graphene electrochemical sensor for quantitative detection of phytotoxic aluminum ions (Al) in soils extracts.

Aluminum in its Al form is a metal that inhibits plant growth, especially in acidic soils (pH < 5.5). Rapid and accurate quantitative detection of Al in agricultural soils is critical for the timely implementation of remediation strategies.