[Delayed convulsion after lidocaine instillation for bronchoscopy].

Introduction: Lidocaine toxicity usually appears rapidly and is directly correlated with plasma concentrations of the drug.

Case Report: We report a case of a late neurologic toxicity occurring after instillation of lidocaine during fibre-optic bronchoscopy. A patient with bronchiolitis obliterans underwent a diagnostic bronchoscopy.

[DRESS syndrome induced by ciprofloxacine].

The Drug rash with hypereosinophilia and systemic symptoms (DRESS) syndrome, or hypersensitivity syndrome, is a severe drug-induced hypersensitivity syndrome. It has been exceptionally described with ciprofloxacin. We report a 47-year-old-woman who developed DRESS syndrome, 2 days after taking ciprofloxacin for a urinary infection.

Facial hyperpigmentation during imatinib therapy for gastrointestinal stromal tumor.

We report a rare case of facial hyperpigmentation during imatinib therapy for a gastrointestinal stromal tumor.

[Accidental shortening time of high dose methotrexate infusion: case report and literature review].

Methotrexate (MTX) is a folic acid antagonist used at high-dose intravenously on 24 hours (24h) in the treatment of the acute lymphoblastic leukemia (ALL). To prevent potential toxicity, MTX is usually administered following the application of preventive measures. We report a case of an accidental shortening time for high dose MTX infusion and a literature review of accidental intoxications by the MTX.

[Auditory hallucinations due to voriconazole: Illustration by plasma monitoring].

Voriconazole is a second-generation azole antifungal that is widely indicated in the treatment of invasive aspergillosis. It is generally well tolerated. It has nevertheless numerous side effects like hepatotoxicity, photosensitivity, skin rashes, and visual disturbances.

[Drug induced colitis: review article].

Frequency of colitis induced by drugs is often under estimated. Antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDS) are usually incriminated. In this study, we classified colitis according to the main responsible drug with a focus on clinical symptomatology, physiopathology, evolution, and complications.