[Femoral hernia].

A femoral hernia descends through the femoral canal beneath the inguinal ligament. Rare in man, it occurs in women over 50. It can be difficult to recognize and any symptoms of the groin may rise the diagnosis.

Contribution of histopathologic and molecular analyses to the diagnosis of cutaneous B-cell infiltrates.

To evaluate the value of morphologic, immunohistochemical and molecular analyses, we studied 21 skin biopsy specimens from 19 patients with primary cutaneous B-cell infiltrates. Morphologic review by two independent dermatopathologists confirmed the consensus diagnoses of lymphoma (n = 6) or benign lymphoid hyperplasia (n = 6). A discordant diagnosis was made for the other samples (n = 9), which were thereafter considered as unclassified lymphoid infiltrates.

Simultaneous development of two different B-cell lymphomas in a patient with acquired immune deficiency syndrome evidenced by molecular analysis.

We report a case of a man positive for the human immunodeficiency virus who rapidly died of lymphoma with cerebral, lung, and pericardic involvement. After autopsy, histopathological study of the different tumor sites showed the same morphological feature of immunoblastic lymphoma, with large areas of necrosis. In situ hybridization showed monotypic kappa light chain mRNA within lung lymphoma cells and monotypic lambda light chain mRNA within cerebral lymphoma cells.

[Diagnostic methods in allergic asthma].

Analysis of the allergic component in asthma results in a critical comparison of the data provided by the interview, skin tests, possibly completed by carefully selected immunological tests and/or bronchial or nasal stimulation tests. For some allergens, it is also possible to study the allergenic environment of these patients. The skin tests allow an easy analysis of the skin mastocytes carrying specific IgE and degranulating after the allergenic extract has been introduced.

Studies on bovine Breda virus.

Diarrheic feces from 21 calves were examined by electron microscopy and 16 contained particles morphologically similar to those of Breda virus. The particles were spherical or elongated, 60-270 nm in greatest dimension and had surface spikes 9-13 nm long. Convalescent serum from a human patient with Breda virus-associated diarrhea reacted with one of the bovine viruses by immune electron microscopy, suggesting a serological resemblance between human and bovine Breda-like viruses.