A multicountry evaluation of the Xpert MTB/RIF assay for the diagnosis of intrathoracic tuberculosis in children using alternative specimens (nasopharyngeal aspirate and stool): A prospective cohort study conducted in Madagascar, Ivory Coast and Cameroon (TB KIDS project).

Objectives: Tuberculosis (TB) diagnosis in children remains challenging due to the paucibacillary nature of specimens and the difficulty in obtaining suitable samples. The use of alternative samples like nasopharyngeal aspirate (NPA) and stools, alongside Xpert MTB/RIF testing, offers promising improvements. This study aimed to assess the diagnostic performance of the Xpert MTB/RIF test on NPA and stool samples for detecting intrathoracic TB in children from Madagascar, Cameroon, and Ivory Coast.

[Ocular burns: epidemiological, clinical, therapeutic and evolutionary aspects at the Cocody University Hospital, Côte d'Ivoire].

Justification: This study describes the socio-demographic characteristics, clinical, therapeutic, and evolutionary aspects of ocular burns to contribute to the improvement of their management.

Method: A retrospective study was conducted in the Ophthalmology Department of the Cocody University Hospital (CHU) in Abidjan, Côte d'Ivoire, from January 1, 2020, to January 31, 2021. It focused on 49 patient records with ocular trauma, including 12 bilateral cases, totaling 61 eyes.

Circulating natural killer cells and their association with breast cancer and its clinico-pathological characteristics.

Purpose: Natural killer (NK) cells play a critical role in cancer immunosurveillance and hold promise as both therapies and prognostic markers in advanced disease. We explore factors that may influence NK cell concentration in the peripheral blood of women with breast cancer in Côte d'Ivoire compared to healthy controls and implications for future research in our context.

Methods: In this cross-sectional case-control study, blood samples were taken from 30 women diagnosed with breast cancer within 6 months of diagnosis and fifteen healthy women at University Teaching Hospital [Centre Hospitalier Universitaire (CHU)] Treichville in Abidjan, Côte d'Ivoire, from March to September 2018.

[Evolution of epidemiology and management of acute coronary syndromes in Abidjan : A cross-sectional study of 1011 patients.].

Background: To assess the evolution of the epidemiology and management of patients hospitalized to Abidjan Heart Institute for acute coronary syndrome (ACS).

Methods: Cross-sectional study comparing two periods: from January 2002 to December 2009 (period 1) and from January 2010 to December 2016 (period 2), including all patients aged 18 years old, admitted to Intensive Care Unit of Abidjan Heart Institute for ACS.

Results: One thousand eleven (1011) patients were included among the 6784 patients admitted to Intensive Care Unit of Abidjan Heart Institute for a cardiovascular disease.

[Prognostic factors for pneumopathy acquired under mechanical ventilation in multi-purpose resuscitation at the Angre CHU (RCI)].

Objectives: To identify the factors of poor prognosis of ventilator-associated lung disease (VAP) in order to improve their management.

Patients And Method: Prospective, descriptive and analytical study of patients admitted to intensive care at the Angré University Hospital from November 1, 2019 to July 31, 2021 and having presented VAP.

Results: We collected 43 patients out of 625 admissions, i.

Dose-effect relation between regular consumption of 100% cocoa powder and blood pressure in young, healthy black Africans.

Background: Some previous works have focused on dose-response relationship between cocoa consumption and blood pressure in Caucasians. As black subjects have lower nitric oxide bioavailability, the aim of this work was to determine the dose-effect relation between cocoa and blood pressure in black Africans.

Method: One hundred and thirty healthy black African males aged 18-30 were randomly assigned into four groups: three groups consuming 10 g, 5 g, or 2 g of cocoa powder daily for three weeks and one control group that did not consume cocoa.

Weekly Physiological Changes in Blood Pressure During Three Weeks Daily Consumption of 10 Grams of Cocoa Powder Among Young Black Africans in Côte d'Ivoire.

Background: In Caucasians, regular consumption of cocoa induces a drop in arterial blood pressure via an increase in nitric oxide (NO) production. However, black individuals have a different NO biodisponibility compared to Caucasians. The aim of this study was to determine, in black Africans, the physiological variations in arterial blood pressure among cocoa consumers.

Gender influence on the MVV / FEVı ratio in a population of healthy young adults.

Introduction: Maximal voluntary ventilation (MVV) and flow expiratory volume in the first second (FEVı) are important spirometric parameters. They are both gender-dependent. However, estimating the MVV, which is widely practiced in cardiopulmonary function testing, by multiplying FEVı by a constant value (equal to MVV/FEVı ratio) does not seem to take this into account.

Physiological variations of blood pressure according to gender and age among healthy young black Africans aged between 18 and 30 years in Côte d'Ivoire, West Africa.

In Africa, abnormal high blood pressure is common and affects young subjects. The risk of organ damage and mortality increases with blood pressure level. Therefore, the purpose of this study was to assess the blood pressure profile of a black African population aged between 18 and 30 years in Côte d'Ivoire.

Human papilloma viruses infection among adolescent females perinatally infected with HIV in Côte d'Ivoire.

Background: Cervical cancer prevention strategies recommend human papilloma virus (HPV) vaccination for female adolescents prior to their sexual debut. While HIV is a major risk factor for HPV infection in women of childbearing age, its prevalence among HIV-infected adolescent female is mostly unknown. This study aimed to describe the HPV prevalence and correlates among perinatally HIV-infected adolescent females prior to HPV immunisation.

[Exceptional Neurological Complication of Snakebite Envenomation: A Case in Mali].

Envenomation by snakebite can lead to hematological, circulatory, digestive, renal, and neurological complications. Brain abscess after snakebite envenomation is exceptional and very rarely reported in the literature. In this article, we describe the clinical case of a 45-year-old woman with no particular history, admitted to our department for vigilance disturbances linked to a motor deficit on the right side and fever after viper bite on the left thumb.

Polyradiculopathies in the neurology department of the Cocody University Hospital, Abidjan, Ivory Coast: epidemiological and clinical profiles and outcomes over a six-year period.

Polyradiculoneuropathies (PRNs) are inflammatory disorders of the peripheral nervous system. They are diffuse in general, sparing neither the proximal portions of the elements of this system, where they predominate, nor the cranial nerves. To describe the epidemiological and diagnostic profiles, as well as the course, of patients with PRN in the Cocody university hospital center (Abidjan) neurology department over the past six years.

[External evaluation of the quality of CD4 T cells enumeration in the laboratory of immunology and hematology at the Cocody University Hospital Center].

Introduction: The rate of T lymphocytes-CD4 (TLR4) is a crucial parameter for therapeutic decision and follow-up in patients with Human Immunodeficiency Virus (HIV) infection. This must be determined in a reliable and accurate way. The laboratory of immunology and hematology at the Cocody University Hospital Center has participated in the External Quality Assessment program (EQAP) for TLR4 enumeration provided by QASI (Quality Assessment and Standardization for Immunological Measures Relevant to HIV/AIDS) in order to deliver quality results.

[Pneumothorax catamenial: results of 18 cases operas].

This study aims to propose a therapeutic approach for catamenial pneumothorax based on outcomes reported in 18 cases. We conducted a retrospective study of 18 female elderly patients with an average age of 32.2 years who had undergone surgery for right (16 cases) and bilateral catamenial pneumothorax (2 cases) from January 1994 to December 2016.

Evolution of hepatocellular carcinoma epidemiology in Côte d'Ivoire.

Introduction: Hepatocellular carcinoma is a major concern for Public health in West Africa. In Côte d'Ivoire, the bulk of our knowledge stems from studies conducted decades ago. Our aim was, thus, to assess whether the epidemiological features of this tumor changed recently.

Characteristics, management, and outcomes of patients with hepatocellular carcinoma in Africa: a multicountry observational study from the Africa Liver Cancer Consortium.

Background: Hepatocellular carcinoma is a leading cause of cancer-related death in Africa, but there is still no comprehensive description of the current status of its epidemiology in Africa. We therefore initiated an African hepatocellular carcinoma consortium aiming to describe the clinical presentation, management, and outcomes of patients with hepatocellular carcinoma in Africa.

Methods: We did a multicentre, multicountry, retrospective observational cohort study, inviting investigators from the African Network for Gastrointestinal and Liver Diseases to participate in the consortium to develop hepatocellular carcinoma research databases and biospecimen repositories.

[Formalized consensus: clinical practice recommendations for the management of the migraine in African adult patients].

Migraine is a primary headache disorder (according to the latest International Headache Society criteria) affecting approximately 8% of African population. Women are more often affected than men and attacks usually occur before the age of 40 years Although some treatments, hygienic-dietary measures and other non-pharmacological methods can reduce the intensity and frequency of attacks, medicinal treatment of migraine attack is often necessary. Availability of treatments and access to care differ in Africa and led to the implementation of the first expert consensus recommendations for the management of the migraine in african adult patients.

[Prevalence and characteristics of metabolic syndrome among hypertensive patients in Abidjan].

Aim: Assess prevalence of metabolic syndrome (MetS) in black Africans hypertensive patients.

Population: Prospective survey from 3rd November 2014 to 12th June 2015, at Abidjan Heart Institute. Study was carried out among patients aged 18 years old, admitted to external consultation.

[Treatment by honey for skin wounds in Abidjan].

Aims: The authors tested the effectiveness of honey on various types of wounds. They report in this work, the preliminary results of their study.

Materials And Methods: This is a prospective study conducted over a period of 12 months in the orthopedic trauma unit of the Cocody Abidjan University Hospital.

[Dynamic of indicators of ambulatory care of tuberculosis in the antituberculous center of Adjamé].

Introduction: Tuberculosis (TB) remains a real problem of public health in Côte d'Ivoire. The aim of our study is to describe the dynamic of anti-TB fight indicators in anti-TB center (CAT) of Adjamé.

Methodology: We realized a retrospective study, comparing the anti-TB activities of two periods (1999-2001 versus 2010-2012) at the CAT of Adjamé.