278 results match your criteria: "centre d'etudes de Saclay[Affiliation]"
Phys Rev E
March 2023
CEA, DAM, DIF, F-91297 Arpajon, France.
We propose a model of ion-electron plasma (or nucleus-electron plasma) that accounts for the electronic structure around nuclei (i.e., ion structure) as well as for ion-ion correlations.
View Article and Find Full Text PDFEur J Pharm Biopharm
January 2023
Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, 91401 Orsay, France. Electronic address:
Introduction: Glioblastoma (GBM) is the most common and deadly form of primary brain tumor. Between 30 % and 60 % of GBM are characterized by overexpression of the Epidermal Growth Factor Receptor (EGFR). The anti-EGFR antibody Cetuximab (CTX) showed a favorable effect for EGFR colorectal cancer but failed to demonstrate efficacy for GBM.
View Article and Find Full Text PDFChemosphere
February 2023
IC2MP, Equipe HydrASA, UMR 7285 CNRS/Université de Poitiers, 86073, Poitiers, France.
In this study, new experimental data for the adsorption of lead onto a swelling clay mineral with a tetrahedral charge (beidellite) at the ultratrace level (<10 M) are presented. The data were interpreted using an ion-exchange multisite model that considers the sorption of major cations (including H), which always compete with trace elements for sorption onto mineral surfaces in natural environments. The ability of the proposed model to predict experimental K values under various conditions of ionic strength (fixed by NaCl solutions) and aqueous cation compositions (including Pb and PbCl) was tested.
View Article and Find Full Text PDFData Brief
December 2022
Institut Pierre Simon Laplace, SU/CNRS, Paris, France.
This paper describes the extension of the previously CMIP5 based high-resolution climate projections with additional ones based on the more recent climate projections from the CMIP6 experiment. The downscaling method and data processing are the same but the reference dataset is now the ERA5-Land reanalysis (compared to ERA5 previously) allowing to increase the resolution of the new downscaled projections from 0.25° x 0.
View Article and Find Full Text PDFPhys Rev Lett
June 2022
INFN, Sezione di Pavia, Pavia, Italy.
The study of nuclei and antinuclei production has proven to be a powerful tool to investigate the formation mechanism of loosely bound states in high-energy hadronic collisions. The first measurement of the production of _{Λ}^{3}H in p-Pb collisions at sqrt[s_{NN}]=5.02 TeV is presented in this Letter.
View Article and Find Full Text PDFPhys Rev Lett
April 2022
INFN, Sezione di Pavia, Pavia, Italy.
The polarization of the Λ and Λ[over ¯] hyperons along the beam (z) direction, P_{z}, has been measured in Pb-Pb collisions at sqrt[s_{NN}]=5.02 TeV recorded with ALICE at the Large Hadron Collider (LHC). The main contribution to P_{z} comes from elliptic flow-induced vorticity and can be characterized by the second Fourier sine coefficient P_{z,s2}=⟨P_{z}sin(2φ-2Ψ_{2})⟩, where φ is the hyperon azimuthal emission angle and Ψ_{2} is the elliptic flow plane angle.
View Article and Find Full Text PDFPhys Rev Lett
March 2022
INFN, Sezione di Pavia, Pavia, Italy.
Nature
February 2022
European Southern Observatory, Santiago, Chile.
In the widely accepted 'unified model' solution of the classification puzzle of active galactic nuclei, the orientation of a dusty accretion torus around the central black hole dominates their appearance. In 'type-1' systems, the bright nucleus is visible at the centre of a face-on torus. In 'type-2' systems the thick, nearly edge-on torus hides the central engine.
View Article and Find Full Text PDFPhys Rev Lett
January 2022
INFN, Sezione di Pavia, Pavia, Italy.
The p_{T}-differential production cross sections of prompt D^{0}, Λ_{c}^{+}, and Σ_{c}^{0,++}(2455) charmed hadrons are measured at midrapidity (|y|<0.5) in pp collisions at sqrt[s]=13 TeV. This is the first measurement of Σ_{c}^{0,++} production in hadronic collisions.
View Article and Find Full Text PDFPhys Rev Lett
December 2021
INFN, Sezione di Pavia, Pavia, Italy.
The p_{T}-differential cross sections of prompt charm-strange baryons Ξ_{c}^{0} and Ξ_{c}^{+} were measured at midrapidity (|y|<0.5) in proton-proton (pp) collisions at a center-of-mass energy sqrt[s]=13 TeV with the ALICE detector at the LHC. The Ξ_{c}^{0} baryon was reconstructed via both the semileptonic decay (Ξ^{-}e^{+}ν_{e}) and the hadronic decay (Ξ^{-}π^{+}) channels.
View Article and Find Full Text PDFThe prompt production of the charm baryon Λ_{c}^{+} and the Λ_{c}^{+}/D^{0} production ratios were measured at midrapidity with the ALICE detector in pp and p-Pb collisions at sqrt[s_{NN}]=5.02 TeV. These new measurements show a clear decrease of the Λ_{c}^{+}/D^{0} ratio with increasing transverse momentum (p_{T}) in both collision systems in the range 2
Phys Rev Lett
October 2021
INFN, Sezione di Pavia.
This Letter presents the first experimental evidence of the attractive strong interaction between a proton and a ϕ meson. The result is obtained from two-particle correlations of combined p-ϕ⊕ p[over ¯]-ϕ pairs measured in high-multiplicity pp collisions at sqrt[s]=13 TeV by the ALICE Collaboration. The spin-averaged scattering length and effective range of the p-ϕ interaction are extracted from the fully corrected correlation function employing the Lednický-Lyuboshits approach.
View Article and Find Full Text PDFMagn Reson Imaging Clin N Am
November 2021
Department of Radiology, Nationwide Children's Hospital, 700 Children's Drive - ED4, Columbus, OH 43205, USA. Electronic address:
Noncontrast magnetic resonance imaging techniques for measuring brain perfusion include arterial spin labeling (ASL) and intravoxel incoherent motion (IVIM). These techniques provide noninvasive and repeatable assessment of cerebral blood flow or cerebral blood volume without the need for intravenous contrast. This article discusses the technical aspects of ASL and IVIM with a focus on normal physiologic variations, technical parameters, and artifacts.
View Article and Find Full Text PDFPhys Rev Lett
August 2021
Università di Brescia and Sezione INFN, Brescia, Italy.
The event-by-event correlations between three flow amplitudes are measured for the first time in Pb-Pb collisions, using higher-order symmetric cumulants. We find that different three-harmonic correlations develop during the collective evolution of the medium when compared to correlations that exist in the initial state. These new results cannot be interpreted in terms of previous lower-order flow measurements since contributions from two-harmonic correlations are explicitly removed in the new observables.
View Article and Find Full Text PDFPhys Rev Lett
July 2021
Università di Brescia, Brescia, Italy.
A measurement of dielectron production in proton-proton (pp) collisions at sqrt[s]=13 TeV, recorded with the ALICE detector at the CERN LHC, is presented in this Letter. The data set was recorded with a reduced magnetic solenoid field. This enables the investigation of a kinematic domain at low dielectron (ee) invariant mass m_{ee} and pair transverse momentum p_{T,ee} that was previously inaccessible at the LHC.
View Article and Find Full Text PDFPhys Rev Lett
April 2021
Università di Brescia, Brescia, Italy.
The elliptic flow of electrons from beauty hadron decays at midrapidity (|y|<0.8) is measured in Pb-Pb collisions at sqrt[s_{NN}]=5.02 TeV with the ALICE detector at the LHC.
View Article and Find Full Text PDFData Brief
April 2021
Institut Pierre Simon Laplace, SU/CNRS, Paris, France.
A high-resolution climate projections dataset is obtained by statistically downscaling climate projections from the CMIP5 experiment using the ERA5 reanalysis from the Copernicus Climate Change Service. This global dataset has a spatial resolution of 0.25°x 0.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
November 2020
Laboratoire Léon Brillouin, Université Paris-Saclay, CNRS, Commissariat à l'Energie Atomique et aux Énergies Alternatives Centre d'études de Saclay, F-91191 Gif sur Yvette, France
Phys Rev Lett
October 2020
Università di Brescia, Brescia, Italy.
In this Letter, we report the first measurement of the inelastic cross section for antideuteron-nucleus interactions at low particle momenta, covering a range of 0.3≤p<4 GeV/c. The measurement is carried out using p-Pb collisions at a center-of-mass energy per nucleon-nucleon pair of sqrt[s_{NN}]=5.
View Article and Find Full Text PDFThe first measurement at the LHC of charge-dependent directed flow (v_{1}) relative to the spectator plane is presented for Pb-Pb collisions at sqrt[s_{NN}]=5.02 TeV. Results are reported for charged hadrons and D^{0} mesons for the transverse momentum intervals p_{T}>0.
View Article and Find Full Text PDFPhys Rev Lett
July 2020
Università di Brescia, Brescia, Italy.
The first evidence of spin alignment of vector mesons (K^{*0} and ϕ) in heavy-ion collisions at the Large Hadron Collider (LHC) is reported. The spin density matrix element ρ_{00} is measured at midrapidity (|y|<0.5) in Pb-Pb collisions at a center-of-mass energy (sqrt[s_{NN}]) of 2.
View Article and Find Full Text PDFPhys Rev Lett
March 2020
Università di Brescia, Brescia, Italy.
The study of the strength and behavior of the antikaon-nucleon (K[over ¯]N) interaction constitutes one of the key focuses of the strangeness sector in low-energy quantum chromodynamics (QCD). In this Letter a unique high-precision measurement of the strong interaction between kaons and protons, close and above the kinematic threshold, is presented. The femtoscopic measurements of the correlation function at low pair-frame relative momentum of (K^{+}p⊕K^{-}p[over ¯]) and (K^{-}p⊕K^{+}p[over ¯]) pairs measured in pp collisions at sqrt[s]=5, 7, and 13 TeV are reported.
View Article and Find Full Text PDFJ Phys Chem B
February 2020
UPR9080, Laboratoire de Biochimie Théorique , CNRS, Université de Paris, 13 rue Pierre et Marie Curie , F-75005 Paris , France.
In this work, we combine experiments and molecular simulations to unveil the hidden allosteric propensity of a thermophilic malate dehydrogenase protein (MDH). We provide evidence that, at its working temperature, the nonallosteric MDH takes a compact structure because of internal dewetting and reorganizes the active state toward functional conformations similar to its homologous allosteric LDHs. Moreover, a single-point mutation confers on the MDH a cooperative behavior that mimics an allosteric LDH.
View Article and Find Full Text PDFPhys Rev Lett
November 2019
Università di Brescia, Brescia, Italy.
The first measurement of the ϒ(1S) elliptic flow coefficient (v_{2}) is performed at forward rapidity (2.5
Measurements of anisotropic flow coefficients (v_{n}) and their cross-correlations using two- and multiparticle cumulant methods are reported in collisions of pp at sqrt[s]=13 TeV, p-Pb at a center-of-mass energy per nucleon pair sqrt[s_{NN}]=5.02 TeV, Xe-Xe at sqrt[s_{NN}]=5.44 TeV, and Pb-Pb at sqrt[s_{NN}]=5.
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