The distribution of the transient global amnesia in the province of Ferrara, Italy, a clue to the pathogenesis?

The pathophysiology of transient global amnesia (TGA) is still uncertain. In the province of Ferrara (Fe-province), Italy, given the health organization and the alarming clinical features, the cases of TGA in the resident population virtually correspond to the resident outpatients diagnosed as TGA cases in the ER of the University Hospital of Ferrara. Thanks to this, a retrospective survey identified 35 (14 men, 21 women) first-ever TGA cases in the resident population in 2018 (346,975 inhabitants) giving a crude incidence rate of 10.

Can the age at onset give a clue to the pathogenesis of ALS?

Pathogenesis could play an important role in the mid- to late-life onset of symptoms in amyotrophic lateral sclerosis (ALS). An analysis of the age at onset of ALS among the incident cases occurring in the population in the Health District of Ferrara, Italy, in the period 1064-2009 was carried out. Two subsequent 23-year time intervals (1964-1986 and 1987-2009) were considered.