Ophthalmologic Abnormalities in Children with Congenital Sensorineural Hearing Loss.

To review a single center experience with the diagnosis of visual impairment in patients with sensorineural hearing loss (SNHL) and propose a diagnostic algorithm. Retrospective study of patients with SNHL who were diagnosed with ophthalmologic abnormalities in the course of evaluation. University children's hospital and university-associated eye institute.

Responding to Those Who Hope for a Miracle: Practices for Clinical Bioethicists.

Significant challenges arise for clinical care teams when a patient or surrogate decision-maker hopes a miracle will occur. This article answers the question, "How should clinical bioethicists respond when a medical decision-maker uses the hope for a miracle to orient her medical decisions?" We argue the ethicist must first understand the complexity of the miracle-invocation. To this end, we provide a taxonomy of miracle-invocations that assist the ethicist in analyzing the invocator's conceptions of God, community, and self.

Multiple Local Solutions and Geomin Rotation.

In exploratory factor analysis, factor rotation is conducted to improve model interpretability. A promising and increasingly popular factor rotation method is geomin rotation. Geomin rotation, however, frequently encounters multiple local solutions.

Quality of life among boys with adrenoleukodystrophy following hematopoietic stem cell transplant.

Hematopoietic stem cell transplant (HSCT) is the only accepted treatment capable of halting the progression of X-linked cerebral adrenoleukodystrophy (CALD). While survival and neurological outcomes have been described, there is little information regarding the quality of life (QoL) of transplanted patients with CALD. This analysis is a cross-sectional study of QoL in 16 males diagnosed with CALD who underwent HSCT at a single institution.

Pain interference and depressive symptoms in communicative people with Alzheimer's disease: a pilot study.

Objectives: To examine pain interference in verbally communicative older adults with mild to moderate Alzheimer's disease (AD) and to examine the association of pain interference with cognitive function and depressive symptoms.

Method: For this pilot study, we used a cross-sectional design to examine pain interference (Brief Pain Inventory-Short Form), cognitive function (Mini-Mental State Exam), and depressive symptoms (15-item Geriatric Depression Scale) in 52 older (≥65) communicative adults with AD who reported being free from chronic pain requiring daily analgesics.

Results: Pain was reported to interfere with general activity (13.

A randomized controlled trial of expressive writing in breast cancer survivors with lymphedema.

Objective: Breast cancer survivors who develop lymphedema report poorer quality of life (QoL) than those without lymphedema. Expressive writing is a potential intervention to address QoL.

Design: Adult women (N = 107) with breast cancer and chronic Stage II lymphedema were randomised to writing about thoughts and feelings specific to lymphedema and its treatment (intervention) or about daily activities (control) for four, 20-min sessions.

A 6-year surveillance study of "Stingers" in NCAA American Football.

This study describes the epidemiology of "stinger" injuries in National Collegiate Athletic Association (NCAA) Men's Football. About 57 NCAA Men's Football programmes provided 153 team-seasons of injury data to the NCAA Injury Surveillance Programme (NCAA-ISP) during the 2009/2010-2014/2015 academic years. In the study period, 229 "stingers" were reported for an injury rate of 2.

Gender and Racial Disparities in Cases of Autoenucleation.

Objective: This review demonstrates the gender and racial disparities among patients who have committed ocular autoenucleation.

Design: Peer-reviewed articles were identified and reviewed on the basis of a literature search in PubMed/MEDLINE and Ovid/EMBASE databases from all available literature to date.

Results: We identified 60 cases of autoenucleation published in contemporary literature with nine attempted cases.

A Comprehensive Review of Sex Disparities in Symptoms, Pathophysiology, and Epidemiology of Dry Eye Syndrome.

Introduction: The etiology, frequency, manifestation, and treatment of dry eye syndrome are commonly influenced by sex and gender.

Materials And Methods: This study aims to review the differences in epidemiology, pathophysiology, and associated diseases between the sexes. The terms men and male and women and female are used interchangeably throughout the review to refer to biological sex.

Pneumococcal conjugate vaccine introduction in Latin America and the Caribbean: progress and lessons learned.

In Latin America and the Caribbean, pneumococcus has been estimated to cause 12,000-28,000 deaths, 182,000 hospitalizations, and 1.4 million clinic visits annually. Countries in the Americas have been among the first developing nations to introduce pneumococcal conjugate vaccines into their Expanded Programs on Immunization, with 34 countries and territories having introduced these vaccines as of September 2015.

Changing Medical School IT to Support Medical Education Transformation.

Problem: Many medical schools are modifying curricula to reflect the rapidly evolving health care environment, but schools struggle to provide the educational informatics technology (IT) support to make the necessary changes. Often a medical school's IT support for the education mission derives from isolated work units employing separate technologies that are not interoperable.

Intervention: We launched a redesigned, tightly integrated, and novel IT infrastructure to support a completely revamped curriculum at the Vanderbilt School of Medicine.

Status of portfolios in undergraduate medical education in the LCME accredited US medical school.

Aim: We sought to investigate the number of US medical schools utilizing portfolios, the format of portfolios, information technology (IT) innovations, purpose of portfolios and their ability to engage faculty and students.

Methods: A 21-question survey regarding portfolios was sent to the 141 LCME-accredited, US medical schools. The response rate was 50% (71/141); 47% of respondents (33/71) reported that their medical school used portfolios in some form.

Organ Dose Estimates for Hyperthyroid Patients Treated with (131)I: An Update of the Thyrotoxicosis Follow-Up Study.

The Thyrotoxicosis Therapy Follow-up Study (TTFUS) is comprised of 35,593 hyperthyroid patients treated from the mid-1940s through the mid-1960s. One objective of the TTFUS was to evaluate the long-term effects of high-dose iodine-131 ((131)I) treatment (1-4). In the TTFUS cohort, 23,020 patients were treated with (131)I, including 21,536 patients with Graves disease (GD), 1,203 patients with toxic nodular goiter (TNG) and 281 patients with unknown disease.

Ignoring Clustering in Confirmatory Factor Analysis: Some Consequences for Model Fit and Standardized Parameter Estimates.

In many situations, researchers collect multilevel (clustered or nested) data yet analyze the data either ignoring the clustering (disaggregation) or averaging the micro-level units within each cluster and analyzing the aggregated data at the macro level (aggregation). In this study we investigate the effects of ignoring the nested nature of data in confirmatory factor analysis (CFA). The bias incurred by ignoring clustering is examined in terms of model fit and standardized parameter estimates, which are usually of interest to researchers who use CFA.

Bias in Cross-Sectional Analyses of Longitudinal Mediation: Partial and Complete Mediation Under an Autoregressive Model.

Maxwell and Cole (2007) showed that cross-sectional approaches to mediation typically generate substantially biased estimates of longitudinal parameters in the special case of complete mediation. However, their results did not apply to the more typical case of partial mediation. We extend their previous work by showing that substantial bias can also occur with partial mediation.