The Effects of Curodont Application on Human Gingival Fibroblasts.

To evaluate the cytotoxicity of Curodont (an alternative tooth varnish that promotes remineralization of incipient lesions using a self-assembling peptide P11-4) on soft tissue concerning gingival fibroblasts (GF) and assess survivability, proliferation, and attachment compared to silver diammine fluoride (SDF) and fluoride varnish (FV) as controls. Assessment of cell proliferation, survivability, and attachment was accomplished by studying the effects of varying concentrations of Curodont on gingival fibroblasts. Proliferation, survivability, and attachment were measured using Calcein-AM (a fluorescent dye that labels only living cells) via a microplate reader.

Dental and medical considerations of patients with renal disease.

Often a dentist will have a patient with a complicated medical condition that needs to be considered when providing treatment. Following is an in-depth discussion of the medical and dental considerations of patients with renal disease.