Outcomes With Radiation Therapy as Primary Treatment for Unresectable Cutaneous Head and Neck Squamous Cell Carcinoma.

Aims: Unresectable cutaneous squamous cell cancer of the head and neck (HNcSCC) poses treatment challenges in elderly and comorbid patients. Radiation therapy (RT) is often employed for locoregional control. This study aimed to determine progression-free survival (PFS) and overall survival (OS) outcomes achieved with upfront RT in unresectable HNcSCC.

Orthopedic Resident Intern Foundations: A Cross-Institutional, Month-Long Skills Training Boot Camp for PGY-1 Residents.

Objective: Orthopedic residents are tasked with rapidly acquiring clinical and surgical skills, especially during their PGY-1 year. However, resource constraints and other factors frequently cause skills training to fall short of established guidelines. We aimed to design and evaluate a cross-institutional, month-long curriculum aimed at pooling resources to optimize training.

Is Specific Consent for Educational Sensitive Exams on Anesthetized Patients Necessary? Arguments for and Against From Canadian Medical Students.

Objective: Discussions related to the importance of seeking specific consent for sensitive (e.g., pelvic, rectal) exams performed on anesthetized patients by medical students have been growing.

Who is coming in? Evaluation of physician performance within multi-physician emergency departments.

Background: This study aimed to examine how physician performance metrics are affected by the speed of other attendings (co-attendings) concurrently staffing the ED.

Methods: A retrospective study was conducted using patient data from two EDs between January-2018 and February-2020. Machine learning was used to predict patient length of stay (LOS) conditional on being assigned a physician of average speed, using patient- and departmental-level variables.

National early warning score 2 plus non-invasive capnography and perfusion index to estimate poor outcomes in emergency departments.

Background: The study of the inclusion of new variables in already existing early warning scores is a growing field. The aim of this work was to determine how capnometry measurements, in the form of end-tidal CO2 (ETCO2) and the perfusion index (PI), could improve the National Early Warning Score (NEWS2).

Methods: A secondary, prospective, multicenter, cohort study was undertaken in adult patients with unselected acute diseases who needed continuous monitoring in the emergency department (ED), involving two tertiary hospitals in Spain from October 1, 2022, to June 30, 2023.

Nyquist Ghost Elimination for Diffusion MRI by Dual-polarity Readout at Low b-values.

Dual-polarity readout is a simple and robust way to mitigate Nyquist ghosting in diffusion-weighted echo-planar imaging but imposes doubled scan time. We here propose how dual-polarity readout can be implemented with little or no increase in scan time by exploiting an observed b-value dependence and signal averaging. The b-value dependence was confirmed in healthy volunteers with distinct ghosting at low b-values but of negligible magnitude at b = 1000 s/mm2.

GradeDiff-IM: An Ensembles Model-based Grade Classification of Breast Cancer.

Cancer grade classification is a challenging task identified from the cell structure of healthy and abnormal tissues. The partitioner learns about the malignant cell through the grading and plans the treatment strategy accordingly. A major portion of researchers used DL models for grade classification.

Multimodal multiview bilinear graph convolutional network for mild cognitive impairment diagnosis.

Mild cognitive impairment (MCI) is a significant predictor of the early progression of Alzheimer's disease, and it can be used as an important indicator of disease progression. However, many existing methods focus mainly on the image itself when processing brain imaging data, ignoring other non-imaging data (e.g.

Platanus occidentalis L. fruit-derived carbon materials for electrochemical potassium storage.

In the post-lithium-ion battery era, potassium-ion batteries (PIBs) have been considered as a promising candidate because of their electrochemical and economic characteristics. However, as an emerging electrochemical storage technology, it is urgent to develop capable anode materials that can be produced at low cost and on a large scale to promote its practical application. Biomass-derived carbon materials as anodes of PIBs exhibit strong competitiveness by their merits of low weight, high stability, non-toxicity, and wide availability.

Dynamic treeline and cryosphere response to pronounced mid-Holocene climatic variability in the US Rocky Mountains.

Climate-driven changes in high-elevation forest distribution and reductions in snow and ice cover have major implications for ecosystems and global water security. In the Greater Yellowstone Ecosystem of the Rocky Mountains (United States), recent melting of a high-elevation (3,091 m asl) ice patch exposed a mature stand of whitebark pine () trees, located ~180 m in elevation above modern treeline, that date to the mid-Holocene (c. 5,950 to 5,440 cal y BP).

Boreal forests are heading for an open state.

The boreal forest biome is warming four times faster than the global average. Changes so far are moderate, but time lags in responses may transiently maintain forest states which are no longer supported by current environmental conditions. Here, we explore whether tree cover dynamics hint at the state to which the biome may be shifting.

A conifer metabolite corrects episodic ataxia type 1 by voltage sensor-mediated ligand activation of Kv1.1.

Loss-of-function sequence variants in , which encodes the voltage-gated potassium channel Kv1.1, cause Episodic Ataxia Type 1 (EA1) and epilepsy. Due to a paucity of drugs that directly rescue mutant Kv1.

The interaction of bacteria and harmonine in harlequin ladybird confers an interspecies competitive edge.

The harlequin ladybird, , is a predatory beetle used globally to control pests such as aphids and scale insects. Originating from East Asia, this species has become highly invasive since its introduction in the late 19th century to Europe and North America, posing a threat to local biodiversity. Intraguild predation is hypothesized to drive the success of this invasive species, but the underlying mechanisms remain unknown.

Nurse Leader Perspectives on Precepting in a Graduate Nursing Administration Practicum.

Objective: To describe practicum experiences as perceived by nurse leader preceptors of graduate students in a nursing administration practicum.

Background: Practicum experiences in graduate nursing administration programs provide students with exposure to the real-life experiences of nurse leaders, bridging the gap between academic knowledge gained and the application of that information to the workplace. The literature lacks best practices for graduate nursing administration practicum experiences.

A Preliminary Qualitative Exploration of the Lived Experiences of Presenteeism Among Taiwanese Nursing Staff.

Objective: The aim of this study was to explore the lived experiences of presenteeism among Taiwanese nursing staffs.

Background: Presenteeism is a subjective and multifaceted experience, but nurses have rarely been invited to provide their own views of presenteeism.

Methods: A qualitative study based on content analysis was conducted.

Psychological Distress as a Mediator Between Work-Family Conflict and Nurse Managers' Professional and Organizational Turnover Intentions.

Objective: This study aimed to investigate the mediating role of psychological distress in the relationship between work-family conflict and nurse managers' (NMs') professional and organizational turnover intentions.

Background: Work-family conflict is prevalent among NMs. It can have a significant impact on their intent to leave their organization and the profession.

The Impact of Professional Governance on Hope, Resilience, and Empowerment.

Objective: The purpose of this cross-sectional descriptive study was to examine the relationship of professional governance, resilience, and empowerment among RNs in clinical practice in 1 healthcare system.

Background: Given the emotional and physical demands of nursing, especially in recent years, exploring ways that hope-inducing and resilience-building models can support professional practice is vital to the current and future nursing workforce.

Methods: An anonymous survey consisting of demographic questions, the Adult Hope Scale, Connor-Davidson Resilience Scale, and the Conditions for Work Effectiveness Questionnaire II was offered to 1450 RNs in a nonprofit community-based healthcare system for volunteer participation.

Nurse Leader Perspectives and Experiences on Caregiver Support Following a Serious Medical Error.

Objective: This study explored nurse leaders' perspectives and experiences in supporting nurses following a serious medical error.

Background: Appropriate support is crucial for nurses following an error. Authentic leadership provides an environment of psychological safety and establishes a patient safety culture.

Practical Steps Supporting Professional Publications for Leadership and Teams.

Disseminating research or evidence-based practice is not straightforward. As more clinical nurses, executive nurse leaders, nurse scientists, and faculty contribute to new knowledge, there is an increasing need to support the processes to publish and disseminate manuscripts to advance healthcare. Nurse administrators and leaders are key influencers and supporters to bolster expertise and resources to publish.

Natural Densitals.

The concept of natural densitals (NDs) and their amplitudes is introduced. These quantities provide the spectral decomposition of the cumulant of the two-electron density that, by definition, quantifies the extent of electron correlation. Consequently, they are ideally suited for a rigorous description of electron correlation effects in Coulombic systems.

Intraoperative Anesthetic Care During Emergent/Urgent Craniotomy or Craniectomy for Intracranial Hypertension or Herniation: A Systematic Review.

This systematic review aimed to identify and describe best practice for the intraoperative anesthetic management of patients undergoing emergent/urgent decompressive craniotomy or craniectomy for any indication. The PubMed, Scopus, EMBASE, and Cochrane databases were searched for articles related to urgent/emergent craniotomy/craniectomy for intracranial hypertension or brain herniation. Only articles focusing on intraoperative anesthetic management were included; those investigating surgical or intensive care unit management were excluded.

Earth to Ashes: Cultural Transformations in the Cremation Rites of Modern and Contemporary South Korea.

Under Japanese rule in 1912, cremation was legalized in Korea, marking a shift from a strictly prohibited practice to an accepted funeral option. Initially viewed as a Japanese custom, cremation gradually transformed into a "civilized" choice, a perspective pushed by Japanese colonial authorities and some Korean modernizers. However, this narrative overlooks the gradual acceptance of cremation among Koreans.