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SOCS-1 1478 CA/del gene polymorphism affects survival in colorectal carcinoma.
Niger J Clin Pract
March 2022
Department of Pathology, are the part of School of Medicine of Ululudag University, Bursa, Turkey.
Aims And Background: Suppressor of cytokine signaling 1 (SOCS1) is a prototype molecule of the SOCS family. Alterations in the SOCS1 expression have been reported in human cancers and some studies suggest that SOCS1 might act as a tumor suppressor in carcinogenesis. In the present study, we aimed to evaluate the association of SOCS1 promoter -1478CA/del gene polymorphism detected in DNA isolated from the tissues of patients with colorectal cancer (CRC) for histopathological characteristics and survival.
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