Adherence to Brain Trauma Foundation Guidelines for Management of Traumatic Brain Injury Patients and Its Effect on Outcomes: Systematic Review.

Traumatic brain injury (TBI) management based on Brain Trauma Foundation (BTF) guidelines is widely accepted and thought to improve outcome. The objectives of this study are to provide an overview of adherence to BTF guidelines and to explore which factors influence adherence. We conducted a search of relevant electronic bibliographic databases.

Adherence to Brain Trauma Foundation guidelines for management of traumatic brain injury patients: study protocol for a systematic review and meta-analysis.

Background: Traumatic brain injury (TBI) is a leading cause of death and disability around the world. Management based on Brain Trauma Foundation (BTF) guidelines is widely accepted and thought to improve outcome. The objectives of this systematic review are to give an overview of adherence to the BTF guidelines, describe factors influencing adherence, and study the effect of guideline-based management on outcome.

Programmatic variation in home hemodialysis in Canada: results from a nationwide survey of practice patterns.

Background: Over 40% of patients with end stage renal disease in the United States were treated with home hemodialysis (HHD) in the early 1970's. However, this number declined rapidly over the ensuing decades so that the overwhelming majority of patients were treated in-centre 3 times per week on a 3-4 hour schedule. Poor outcomes for patients treated in this fashion led to a renewed interest in home hemodialysis, with more intensive dialysis schedules including short daily (SDHD) and nocturnal (NHD).

The dog model of left ventricular remodeling after myocardial infarction.

Background: For over a century, the dog model has been used widely in research studying cardiovascular physiology pertinent to humans. It has been specially applied, over the past 2 decades, in research on the pathophysiology and treatment of left ventricular (LV) remodeling and heart failure.

Methods And Results: Because progressive LV remodeling and the march to heart failure are major problems facing myocardial infarction (MI) survivors, the dog model of acute MI was modified for the study of LV structural remodeling and dysfunction during post-MI healing (especially anterior MI).