Unusual combination of total occlusion of left main coronary artery and heart failure with pulmonary hemosiderosis: case report.

A case of total occlusion of the left main coronary artery, congestive heart failure, and pulmonary hemosiderosis in a 54-year-old man is reported. Cardiac catheterization showed total occlusion of the left main coronary artery, subtotal occlusion of the right coronary artery, severely deranged hemodynamics, and an akinetic left ventricle except for a hypokinetic posterobasal segment. A radionuclide left ventricular performance study revealed an ejection fraction of 0.

Noninvasive assessment of the Ionescu-Shiley pericardial xenograft in the mitral position: preliminary experience.

To establish noninvasive criteria for assessment of the Ionescu-Shiley pericardial xenograft in the mitral position, 29 patients with a normally functioning bioprosthesis were studied with m-mode echocardiography and phonocardiography. Two-dimensional echocardiograms were also obtained in ten of the patients. Although two-dimensional echocardiography provided simultaneous visualization of a greater number of stents and leaflets than the m-mode technique, the superior resolution of m-mode ultrasound permitted more detailed analyses of the xenograft's motion patterns.

Post-exercise potentiation of wall motion to identify myocardial viability.

Resting left ventricular wall motion abnormalities may represent myocardial scars or areas of viable muscle which are ischemic and may thus benefit from revascularization surgery. Improvement in wall motion in the 3-6 minute post-exercise recovery period as compared to the resting state was investigated as a possible criterion to predict myocardial viability in 168 patients with coronary artery disease. Of 125 patients with abnormal resting wall motion, 14 of 14 who improved regional function post-exercise also improved following coronary bypass surgery.

Calcium antagonists: A new class of therapeutic agents.

A new class of therapeutic agents, sharing inhibition of the slow calcium channel, will soon be available to the American patient. Selective action of these agents upon the atrioventricular node, the smooth muscle of coronary and peripheral arteries, and the contractility of cardiac muscle opens new vistas in cardiovascular pharmacology. Early release of these agents by the Federal Drug Administration for general use is urged, based upon the already wide and successful experience in the European and South American continents.

Left ventricular volumes and ejection fraction derived from apical two-dimensional echocardiography.

Two-dimensional echocardiographic data in orthogonal apical projections were used to calculate left ventricular ejection fraction and volumes in 18 patients, 10 of whom had asynergy. The left ventricular chamber was modeled as a stack of 20 elliptical discs in order to minimize errors associated with assumptions of regular geometry. Calculations were compared to data from biplane angiography and yielded correlation coefficients of 0.

The value of electrocardiographic R-wave changes in exercise testing: Preexercise versus postexercise measurements.

To determine the usefulness of R-wave amplitude changes during exercise testing for the diagnosis of coronary artery disease (CAD) and to understand the discrepancies that have been described in the literature regarding their value, we studied two groups of patients by means of electrocardiographic (EKG) treadmill testing and coronary arteriography. Group I was composed of 149 patients who were studied prospectively. The specificity of R-wave changes measured from preexercise to immediately postexercise (SRV(5)) was 81%, but that of R-wave changes measured from preexercise to peak exercise (URV(5)) was 46%.

Echocardiographic assessment of the Ionescu-Shiley pericardial xenograft in the aortic position.

Echocardiograms of 30 patients with a normally functioning Ionescu-Shiley pericardial xenograft valve in the aortic position were analyzed to delineate the ultrasonic patterns produced by this bioprosthesis. The pericardial leaflets were recorded as thin, discrete echoes that were similar in configuration to the native aortic valve. Maximum systolic excursion of the anterior and posterior leaflets was 19 +/- 0.

Technique for evaluating left ventricular performance with apical two-dimensional echocardiography: Progress report.

A technique of modelling the left ventricle for the purpose of volume determination has been devised. Two-dimensional echocardiographic data from the apical four chamber and two chamber views are used to pattern the ventricle as a stack of elliptical discs. The method has been validated for an array of regular geometric shapes commonly associated with ventricular architecture.

Noninvasive assessment of the stenotic mitral valve orifice by two-dimensional echocardiography.

Two-dimensional echocardiographic imaging of the mitral valve orifice was attempted in 26 patients with isolated mitral stenosis. The intention was to examine further the clinical usefulness and limitations of this technique for estimating the severity of mitral stenosis. Technically adequate recordings of the mitral orifice were obtained in 20 patients (77%).

Infarct-induced wall motion abnormalities in aortocoronary bypass patients: Correlation with electrocardiographic, enzymatic, and scintigraphic diagnostic criteria.

Gated isotope ventriculograms performed 7 to 12 days postoperatively in 50 aortocoronary bypass patients with perioperative myocardial infarction (POMI) were compared with preoperative contrast ventriculograms. The diagnosis of POMI was based on serial electrocardiograms (EKGs), cardiac enzyme studies, and (99m)Tc-pyrophosphate (PYP) scintigraphy. Seven patients exhibited no new regional wall motion abnormalities.

Two-dimensional echocardiography in the diagnosis of unusual left atrial myxomas.

In two patients with atypical myxomas of the left atrium, two-dimensional echocardiography furnished valuable diagnostic information. In one patient, who had previously developed an embolism at the right brachial artery, M-mode echocardiography revealed an abnormal band of echoes within the left atrium. Two-dimensional echocardiography showed a globular cluster of echoes that remained within the left atrial cavity throughout the cardiac cycle; left ventricular angiography confirmed the ultrasonic findings of an intraatrial mass.

Recurrent myocardial infarction in a patient with Prinzmetal's angina and normal coronary arteries.

A 55-year-old man was referred for the evaluation of frequent chest pain and syncope. While in the hospital, he experienced severe chest pain accompanied by transient ST segment elevation and a slight elevation of cardiac enzyme levels. Multiple coronary arteriograms were recorded at various times during an interval of 2 months.

Unusual findings of asymmetrical septal hypertrophy associated with calcification of the interventricular septum: Case report.

A patient with aortic regurgitation, stenosis, and calcification of the septum is reported. Results of echocardiography revealed asymmetrical septal hypertrophy without other features of idiopathic hypertrophic subaortic stenosis. There was no subaortic obstruction evident on cardiac catheterization and angiography.

ECHO-PHONOCARDIOGRAPHIC CHARACTERISTICS OF THE NORMALLY FUNCTIONING COOLEY-CUTTER MITRAL VALVE PROSTHESIS.

Echocardiographic and phonocardiographic records of 19 patients with a normally functioning Cooley-Cutter mitral valve were analyzed in order to provide quantitative baseline values for this prosthesis. The average duration between the second heart sound and peak opening of the valve (A(2)-OC interval) was 83 +/- 4 (standard error of the mean) msec. The Q-CC interval (from the electrocardiographic Q wave to closure of the valve) was 71 +/- 2 msec.

CARDIOGENIC ACUTE RENAL FAILURE (CARF) FOLLOWING OPEN-HEART SURGERY.

Although previous reports have attributed acute renal failure (ARF) following cardiovascular surgery to acute tubular necrosis (ATN), little emphasis has been placed on renal failure due to congestive heart failure (CARF). Of 100 cases of ARF studied prospectively over an 18-month period, 36 occurred after open-heart surgery. Nineteen of these cases were associated with heart failure.

ACOUSTIC CHANGES IN NORMALLY FUNCTIONING MITRAL VALVE PROSTHESES: ECHO-PHONOCARDIOGRAPHIC OBSERVATIONS.

This study confirms previous findings of variability in the intensity of the closing click (CC) as a consequence of premature valve closure. Such alterations have been described as a normal phenomenon in several prosthetic valve models. Combined echo-phonocardiography is of particular value in evaluating prosthetic valve function in patients with unusual and confusing auscultatory changes.

IDENTIFICATION OF LARGE LEFT ATRIAL THROMBUS BY CROSS-SECTIONAL AND M-MODE ECHOCARDIOGRAPHY.

In addition to a typical pattern indicative of mitral stenosis, the M-mode echo-cardiogram of a patient with mitral valve disease revealed a broad band of dense echoes within an enlarged left atrial cavity that was suggestive of an intraatrial thrombus. Subsequent cross-sectional echocardiography demonstrated a globular cluster of echoes inside the left atrial cavity, thus corroborating our interpretation of the M-mode recording. When open mitral commissurotomy was performed, a large, partially calcified thrombus was found protruding from the posterior wall and left atrial appendage into the atrial cavity.

ANGIOSARCOMA OF THE HEART.

A case of primary angiosarcoma arising in the right atrium is described. The clinical, pathological, therapeutic and prognostic features are discussed. A review of the literature reveals 52 cases to date, including the present case.

UNUSUAL CASE OF PULMONARY ARTERIOVENOUS FISTULA CONCEALED BY THE CARDIAC SILHOUETTE ON CHEST ROENTGENOGRAM.

A large pulmonary arteriovenous fistula was discovered in a patient with long-standing cyanosis, clubbing and dyspnea, with no other cardiovascular signs or symptoms and a normal chest roentgenogram at the time of cardiac catheterization and pulmonary angiography. The fistula was overshadowed by the cardiac silhouette. Surgical resection was successful.