2 results match your criteria: "and the Pennington Biomedical Research Center[Affiliation]"

FTO genotype, dietary protein, and change in appetite: the Preventing Overweight Using Novel Dietary Strategies trial.

Am J Clin Nutr

May 2014

Departments of Nutrition (TH, QQ, FBH, FMS, and LQ) and Epidemiology (FBH), Harvard School of Public Health, Boston, MA; the Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (YL, FBH, and LQ); and the Pennington Biomedical Research Center of the Louisiana State University System, Baton Rouge, LA (GAB and DAW).

Background: A common obesity-risk variant rs9939609 in the fat mass- and obesity-associated (FTO) gene was recently shown to affect appetite, and the gene is sensitive to the regulation of amino acids.

Objective: We examined the interaction between FTO genotype and protein intake on the long-term changes in appetite in a randomized controlled trial.

Design: We genotyped FTO rs9939609 in 737 overweight adults in the 2-y Preventing Overweight Using Novel Dietary Strategies trial and assessed 4 appetite-related traits including cravings, fullness, hunger, and prospective consumption.

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Background: Phytosterol supplementation of 2 g/d is recommended by the National Cholesterol Education Program to reduce LDL cholesterol. However, the effects of different intakes of phytosterol on cholesterol metabolism are uncertain.

Objective: We evaluated the effects of 3 phytosterol intakes on whole-body cholesterol metabolism.

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