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Reasons for Patient Call-backs while being Treated with Topical 5-fluorouracil: A Retrospective Chart Review.

J Clin Aesthet Dermatol

June 2023

Dr. Feldman is with the Department of Pathology at Wake Forest School of Medicine in Winston-Salem, North Carolina, the Department of Social Sciences and Health Policy at the Wake Forest School of Medicine in Winston-Salem, North Carolina, and the Department of Dermatology at the University of Southern Denmark in Odense, Denmark.

Objective: To assess the frequency and character of adverse events (AE) associated with 5-FU and compare rate of these events to topical tacrolimus, another irritating topical treatment, as a control.

Methods: Patients prescribed 5-FU for Actinic keratosis (AK) between 1/2015 to 10/2021 were contacted via phone to assess frequency of AE and why they did or did not contact their dermatologist via retrospective chart review. A similar retrospective chart review was done for patients prescribed topical tacrolimus between 1/2015 to 10/2021.

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