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Impact of Lifelong Exercise Training Dose on Ventricular-Arterial Coupling.
Circulation
December 2018
Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, and University of Texas Southwestern Medical Center (M.H., E.H., S.S., N.F., PS.B., J.L.H., T.T., S.S., Q.F., R.Z., B.D.L.).
Background: The dynamic Starling mechanism, as assessed by beat-by-beat changes in stroke volume and left ventricular end-diastolic pressure, reflects ventricular-arterial coupling. It deteriorates with age, and is preserved in highly trained masters athletes. Currently, it remains unclear how much exercise over a lifetime is necessary to preserve efficient ventricular-arterial coupling.
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