2 results match your criteria: "and University of Sydney and Royal Prince Alfred Hospital[Affiliation]"
Frequency and Determinants of Flare and Persistently Active Disease in a Large Multinational Prospective Lupus Cohort.
ACR Open Rheumatol
March 2025
The University of Melbourne and St Vincent's Hospital Melbourne, Melbourne, Victoria, and University of Sydney and Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
Objective: In contrast to relapsing-remitting patterns, persistently active disease (PAD) is a disease activity pattern in patients with systemic lupus erythematosus (SLE) that is inadequately studied. We sought to identify the frequency and determinants of flare and PAD in SLE.
Methods: Flare was defined using the Safety of Estrogens in Lupus Erythematosus National Assessment version of the Systemic Lupus Erythematosus Disease Activity Index (SELENA-SLEDAI flare index), and PAD was defined as an SLEDAI-2K score of ≥4, excluding serology only, on two or more consecutive visits with a maximum six-month interval.
The Neural Signature of Impaired Dual-Tasking in Idiopathic Rapid Eye Movement Sleep Behavior Disorder Patients.
Mov Disord
September 2020
ForeFront Research Team, Brain and Mind Centre, University of Sydney, Camperdown, New South Wales, Australia.
Unlabelled: Dual-task gait can be a useful biomarker for cognitive decline and a sensitive predictor of future neurodegeneration in certain clinical populations, such as patients with idiopathic rapid eye movement sleep behavior disorder.
Objectives: The objective of this cross-sectional study was to determine the neural signature of dual-tasking deficits in idiopathic rapid eye movement sleep behavior disorder using a validated gait paradigm.
Methods: Fifty-eight participants (28 controls; 30 idiopathic rapid eye movement sleep behavior disorder patients) were recruited; 52 participants had functional MRI scans as they performed a validated dual-task virtual reality gait paradigm using foot pedals.