6 results match your criteria: "and University Hospital Medical Center[Affiliation]"
Recommendations for optimal interdisciplinary management and healthcare settings for patients with rare neurological diseases.
Orphanet J Rare Dis
February 2024
Institute of Systems Motor Science, University of Lübeck, Lübeck, Germany.
Article Synopsis
- The German Academy for Rare Neurological Diseases (DASNE) was established in 2017 to improve personalized care for patients with rare neurological diseases (RND) by creating a national network of expert professionals.
- A collaborative Delphi process engaged 37 experts and stakeholders to identify and rank key topics for optimal patient care, resulting in a set of 38 recommendations.
- The finalized recommendations cover various aspects of RND management, including healthcare structure, interdisciplinary collaboration, diagnostics, and patient advocacy, aimed at enhancing the overall treatment landscape for these conditions.
Circulating macrophages as the mechanistic link between mosaic loss of Y-chromosome and cardiac disease.
Cell Biosci
July 2023
Department of Pediatrics, Morgan Stanley Children's Hospital, Columbia University, 3959 Broadway, New York, NY, 10032, USA.
Background: Genetics evidences have long linked mosaic loss of Y-chromosome (mLOY) in peripheral leukocytes with a wide range of male age-associated diseases. However, a lack of cellular and molecular mechanistic explanations for this link has limited further investigation into the relationship between mLOY and male age-related disease. Excitingly, Sano et al.
View Article and Find Full Text PDFMosaic loss of chromosome Y in peripheral blood cells is associated with age-related macular degeneration in men.
Cell Biosci
May 2022
Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences, and University Hospital Medical Center, West Chang'an 620, District Chang'an, Xi'an, 710119, People's Republic of China.
Background: Age-related macular degeneration (AMD) is the leading cause of severe vision loss in patients over 55 years old in the industrialized world. In the past 20 years, approximately 288 million patents have been affected by this disease. Despite this high prevalence, the molecular mechanism for AMD remains unclear, and there remains no effective treatment for this disease.
View Article and Find Full Text PDFEnhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer.
Cancer Lett
July 2022
Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium (DKTK), Freiburg, and German Cancer Research Center (DKFZ), Heidelberg, Germany; Signalling Research Centres BIOSS and CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Germany. Electronic address:
Metastatic small cell lung cancer (SCLC) is not curable. While SCLC is initially sensitive to chemotherapy, remissions are short-lived. The relapse is induced by chemotherapy-selected tumor stem cells, which express the AC133 epitope of the CD133 stem cell marker.
View Article and Find Full Text PDFRetraction notice to "Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer" [Canc. Lett. 520 (2021) 385-399].
Cancer Lett
July 2022
Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; BIOSS Center for Biological Signalling Studies, University of Freiburg, Germany; Signalling Research Centres BIOSS and CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Germany.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
View Article and Find Full Text PDFRETRACTED: Enhanced AC133-specific CAR T cell therapy induces durable remissions in mice with metastatic small cell lung cancer.
Cancer Lett
November 2021
Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; BIOSS Center for Biological Signalling Studies, University of Freiburg, Germany; Signalling Research Centres BIOSS and CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, Germany.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
View Article and Find Full Text PDF