21 results match your criteria: "and St. Thomas's Dental Institute[Affiliation]"
BMJ Clin Evid
November 2013
King's College London at Guy's, King's and St Thomas's Dental Institute, London, UK.
Introduction: Candida is a fungus present in the mouths of up to 60% of healthy people, but overt infection is associated with immunosuppression, diabetes, broad-spectrum antibiotics, and corticosteroid use. In most people, untreated candidiasis persists for months or years unless associated risk factors are treated or eliminated. In neonates, spontaneous cure of oropharyngeal candidiasis usually occurs after 3 to 8 weeks.
View Article and Find Full Text PDFBMJ Clin Evid
February 2012
King's College London at Guy's, King's and St Thomas's Dental Institute, London, UK.
Introduction: Candida is a fungus present in the mouths of up to 60% of healthy people, but overt infection is associated with immunosuppression, diabetes, broad-spectrum antibiotics, and corticosteroid use. In most people, untreated candidiasis persists for months or years unless associated risk factors are treated or eliminated. In neonates, spontaneous cure of oropharyngeal candidiasis usually occurs after 3 to 8 weeks.
View Article and Find Full Text PDFBMJ Clin Evid
March 2009
King's College London at Guy's, King's and St Thomas's Dental Institute, London, UK.
Introduction: Candida is present in the mouths of up to 60% of healthy people, but overt infection is associated with immunosuppression, diabetes, broad-spectrum antibiotics, and corticosteroid use. In most people, untreated candidiasis persists for months or years unless associated risk factors are treated or eliminated. In neonates, spontaneous cure of oropharyngeal candidiasis usually occurs after 3-8 weeks.
View Article and Find Full Text PDFClin Evid
June 2006
King's College London at Guy's, King's and St Thomas's Dental Institute, London, UK.
J Dent
November 2006
Department of Periodontology and Preventive Dentistry, Guy's King's and St Thomas's Dental Institute, Floor 21, Guy's Tower, London Bridge, UK.
Unlabelled: Mercury released from the surface of amalgam fillings has been linked to a variety of disorders, but without proof of correlation. Studies use surface counts to estimate this variable, but large-scale studies would require a tool to rapidly and accurately assess restoration surface area.
Objectives: This study investigated digital analysis of conventional dental radiographs as a means of estimating amalgam surface area.
Clin Evid
June 2005
Guy's, King's College, and St Thomas's Dental Institute, London, UK.
Br J Oral Maxillofac Surg
December 2005
Guy's King's and St Thomas's Dental Institute, Department of Oral and Maxillofacial Surgery, Floor 23 Guy's Tower, Guy's Hospital, London, UK.
The general surgeon, Wilfred Trotter (1872-1939), earned a reputation for his advances in head and neck surgery and his important contribution to the founding concepts of bio-sociology. He pioneered an operation for resection of tumours of the oropharynx, which he published in 1920. He also recognised the importance of total excision of tumours regardless of anatomical boundaries.
View Article and Find Full Text PDFClin Evid
December 2004
Guy's, King's College, and St Thomas's Dental Institute, London, UK.
Clin Evid
December 2003
Guy's, King's College, and St Thomas's Dental Institute, London, UK.
Clin Evid
June 2003
Guy's, King's College, and St. Thomas's Dental Institute, London, UK.
Am J Pathol
March 2003
Head and Neck Cancer Research Program, Guy's, King's, and St. Thomas's Dental Institute, King's College London, London, United Kingdom.
The cytoskeleton in keratinocytes is a complex of highly homologous structural proteins derived from two families of type I and type II polypeptides. Keratin K2e is a type II polypeptide that is expressed in epidermis late in differentiation. Here we report the influence of keratinocyte activation, proliferation, and keratinization on K2e expression in samples of cutaneous and oral lesions.
View Article and Find Full Text PDFClin Evid
June 2002
Guy's, King's College, and St Thomas's Dental Institute, London, UK.
J Am Geriatr Soc
August 2002
Dental Caries Research Group, Guy's, King's and St Thomas's Dental Institute, London, United Kingdom.
Objectives: To determine the effects of a medicated chewing gum on the oral health of frail older people.
Design: A controlled, double-blind trial using three groups based on random allocation of residential homes.
Setting: Sixteen residential homes in West Hertfordshire, England.
J Clin Periodontol
November 2001
Dental Caries Research Group, Guy's, King's and St Thomas's Dental Institute, London, UK.
Aim: A randomised, controlled, double-blind, clinical trial was conducted to investigate the effect of a chlorhexidine acetate/xylitol gum (ACHX) on the plaque and gingival indices of 111 elderly occupants in residential homes. A gum containing xylitol alone (X) and a no gum (N) group was included. Participants' opinions about chewing gum were also investigated.
View Article and Find Full Text PDFJ Endod
October 2001
Guy's, King's, and St. Thomas's Dental Institute, London, UK.
The purpose of this study was to determine the effectiveness of ultrasonic vibration in the removal of fractured posts from teeth under true clinical conditions. Thirty patients (16 men and 14 women with a mean age of 51 yr, SD 13.13) had ultrasonic vibration applied to the side of a fractured post fragment after creation of a small gutter around the fragment.
View Article and Find Full Text PDFDentomaxillofac Radiol
September 2001
Department of Dental Radiology, Guy's King's and St Thomas's Dental Institute, London, UK.
Objectives: To determine the rate of appropriate requests for panoramic radiography (PR) in a Dental Accident and Emergency Department and the implications for patient dose.
Methods: Two hundred and seventy-one requests for PR during July 1998 were assessed by two dental radiologists and categorised as appropriate or inappropriate based on established selection criteria. Incidental findings that might alter patient management were also noted.
J Oral Pathol Med
January 2001
Department of Oral Pathology, Guy's, King's and St Thomas's Dental Institute, London, England.
A variable response following ductal ligation of feline salivary glands corresponds to the human condition but contrasts with a predictable atrophy in obstructed salivary glands of rodents popularly used as a model for human salivary problems. The present investigation is concerned with a possible reason for the variable response, namely the preservation of the innervation. Ducts of feline submandibular and sublingual salivary glands were ligated with or without the inclusion of the chorda tympani.
View Article and Find Full Text PDFCaries Res
February 2001
Guy's, King's and St. Thomas's Dental Institute, Guy's Hospital, London, UK.
A randomized controlled clinical study was set up to assess caries removal following tunnel preparation (test group) and class II cavity preparation (control group). Sixty approximal lesions in adult posterior teeth, visible in the outer third of dentine on bite-wing radiographs, were referred for operative treatment. Initial dentine samples were taken on entry to the lesions in both groups.
View Article and Find Full Text PDFCaries Res
February 2001
Guy's, King's and St. Thomas's Dental Institute, Guy's Hospital, London, UK.
A clinical study was carried out to assess relationship between the presence of approximal cavitation, the radiographic depth of the lesion, the site-specific gingival index and the level of infection of the dentine. Adult patients assessed as needing operative treatment and presenting with approximal lesions visible in the outer third of dentine on bite-wing radiographs were included in the study. Direct lesion depth measurements were recorded from the radiographs and the site-specific gingival index adjacent to the lesion was noted.
View Article and Find Full Text PDFArch Oral Biol
November 2000
Department of Oral Pathology, The Rayne Institute, Guy's, King's and St Thomas's Dental Institute, 123 Coldharbour Lane, SE5 9NU, London, UK.
Twenty-nine parotids ligated for between 1 and 365 days were examined by light and electron microscopy. Major changes in the acini were seen at 4 days and included vacuolation, disintegration, extravasation, apoptosis, phagy and a reduction in number and size of secretory granules. There was a further reduction in secretory granules from 7 to 12 days, but acinar cells persisted even up to 365 days, some contained a luminal concentration of small secretory granules and occasionally acinar cells of a similar appearance to normal were found.
View Article and Find Full Text PDFJ Clin Periodontol
April 2000
Guy's, King's and St. Thomas's Dental Institute, King's College London.
Objective: To compare the progression of periodontal destruction in people with and without HIV.
Method: Relative attachment loss on 6 index teeth was compared between 19 people with HIV and 17 people without HIV infection over 12 and 18 month follow ups.
Results: The proportions of sites with 1, 2 or 3 mm of relative attachment loss were similar in the study and control groups.