2 results match your criteria: "and Sheffield Trophoblastic Disease Centre[Affiliation]"

Influence of age as a factor in the outcome of gestational trophoblastic neoplasia.

J Reprod Med

August 2008

Department of Gynecological Oncology, Sheffield Teaching Hospitals NHS Trust, and Sheffield Trophoblastic Disease Centre, Sheffield, UK.

Objective: To question whether older patients have a worse prognosis or poorer outcomes with chemotherapeutic regimens.

Study Design: All gestational trophoblastic disease (GTD) cases registered between January 1986 and September 2006 (n = 8,536) were reviewed and stratified for age. Chi2 analysis was used to ascertain whether significant differences existed with regard to patient age and histologic diagnosis or treatment requirement.

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Epithelioid trophoblastic tumor: a review of the literature.

J Reprod Med

July 2008

Department of Gynecological Oncology, Sheffield Teaching Hospitals NHS Trust, and Sheffield Trophoblastic Disease Centre, Sheffield, UK.

Objective: To identify common characteristics and provide suggestions for future reporting and management of epithelioid trophoblastic tumors (ETTs).

Study Design: Definitions and treatment strategies are unclear because of low incidence and paucity of reported data. Literature search revealed 52 cases of ETT; 67% presented with abnormal vaginal bleeding, 36% had prior evidence of molar pregnancy and 35% presented with metastases.

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