3 results match your criteria: "and School of Biomedical Sciences Queensland University of Technology[Affiliation]"

Background: Recent epidemics of Zika virus (ZIKV) in the Pacific and the Americas have highlighted its potential as an emerging pathogen of global importance. Both Aedes (Ae.) aegypti and Ae.

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Rodent and cell-culture models support a role for iron-related adipokine dysregulation and insulin resistance in the pathogenesis of nonalcoholic fatty liver disease (NAFLD); however, substantial human data are lacking. We examined the relationship between measures of iron status, adipokines, and insulin resistance in patients with NAFLD in the presence and absence of venesection. This study forms part of the Impact of Iron on Insulin Resistance and Liver Histology in Nonalcoholic Steatohepatitis (IIRON2) study, a prospective randomized controlled trial of venesection for adults with NAFLD.

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Article Synopsis
  • The study focuses on how hepcidin and ferroportin work together in the body and how this affects iron-related health problems.
  • Researchers created special tools to better understand how a new mutation in ferroportin affects its ability to move iron in cells.
  • Findings show that the mutation disrupts normal iron transport and that the new tools can help improve treatments for iron-related diseases.
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